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T82151Hyaluronan-binding peptide, biotin labeled;化合物 Hyaluronan-binding peptide, biotin labeledHyaluronan-
Biotin-labeled Hyaluronan-binding Peptide is a biologically active peptide conjugated with biotin via a C-terminal GGGSK linker. It interacts with the non-sulfated glycosaminoglycan hyaluronan (HA), prominent in the extracellular matrix and on cellular surfaces, involved in processes such as fertilization, embryonic development, wound healing, angiogenesis, leukocyte migration, and cancer metastasis. The peptide impedes HA´s interaction with CD44 receptors and curtails T cell proliferation
价 格:¥电议型 号:T82151产 地:中国大陆
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T82059Interphotoreceptor retinoid-binding protein(668-687) TFA;化合物 Interphotoreceptor retinoid-binding pro
Interphotoreceptor retinoid-binding protein(668-687) TFA, a peptide fragment corresponding to amino acids 668-687 of the human interphotoreceptor retinoid-binding protein (IRBP), has been implicated in the induction of uveitis [1].
价 格:¥电议型 号:T82059产 地:中国大陆
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T81356PTBP1-RNA-binding inhibitor P6 TFA;化合物 PTBP1-RNA-binding inhibitor P6 TFAPTBP1 α3-helix derived pept
PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide that acts as an inhibitor for the splicing factor PTBP1, targeting the alternative splicing events this protein regulates. It operates by binding to RNA via PTBP1´s RNA recognition motif [1].
价 格:¥电议型 号:T81356产 地:中国大陆
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T80992Thrombospondin (TSP-1)-derived CD36 binding motif;化合物 Thrombospondin (TSP-1)-derived CD36 binding mo
Thrombospondin-1 (TSP-1)-derived CD36 binding motif is a bioactive peptide cyclized by a disulfide bond, critical for TSP-1-CD36 interaction. Involved in cancer metastasis, tumor adhesion, and angiogenesis, this matrix-bound glycoprotein-origin peptide competitively inhibits platelet aggregation and tumor metastasis.
价 格:¥电议型 号:T80992产 地:中国大陆
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T80233p53 CBS;化合物 p53 CBSp53 Consensus binding sequence;p53 Consensus binding sequence
p53 CBS (p53 Consensus binding sequence), a biologically active peptide, functions as the p53 consensus DNA binding site.
价 格:¥电议型 号:T80233产 地:中国大陆
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T76566Fsh receptor-binding inhibitor fragment(bi-10);化合物 Fsh receptor-binding inhibitor fragment(bi-10)Fsh
FSH receptor-binding inhibitor fragment (bi-10) is a potent antagonist that inhibits the binding of follicle-stimulating hormone (FSH) to its receptor (FSHR), modifying FSH activity at the receptor level. It suppresses ovulation and induces follicular atresia in mice. Furthermore, this compound holds potential for curbing ovarian cancer carcinogenesis by reducing the overexpression of FSHR and estrogen receptor beta (ERβ) in the ovaries [1].
价 格:¥电议型 号:T76566产 地:中国大陆
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T76542ErbB-2-binding peptide;化合物 ErbB-2-binding peptideErbB-2-binding peptide
ErbB-2-binding peptide (HER2-binding peptide), a tumor-targeting peptide, holds potential for cancer research applications [1].
价 格:¥电议型 号:T76542产 地:中国大陆
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T76527Hepatitis B Virus Receptor Binding Fragment;化合物 Hepatitis B Virus Receptor Binding FragmentHepatitis
Hepatitis B Virus Receptor Binding Fragment (hepatitis B peptide 4980), a synthetic peptide analog, specifically binds to Hep G2 cells and is a potential immunogen anticipated to induce protective antibodies through the attachment blockade pathway of virus neutralization [1] [2].
价 格:¥电议型 号:T76527产 地:中国大陆
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T74256PROTAC BRD9-binding moiety 5;化合物 PROTAC BRD9-binding moiety 5PROTAC BRD9-binding moiety 5
PROTAC BRD9-binding moiety 5, a selective binder of BRD9 with an IC50 value of 4.20 μM, is utilized in PROTAC synthesis and exhibits antiproliferative activity against cancer cells [1].
价 格:¥电议型 号:T74256产 地:中国大陆
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T67737gp120-α4β7 binding inhibitor 11;化合物 gp120-α4β7 binding inhibitor 11gp120-α4β7 binding inhibitor 11
gp120-α4β7 binding inhibitor 11 is an anti-HIV agent. gp120-α4β7 binding inhibitor 11 interferes the binding of HIV associated glycoprotein gp12G with the integrin α4β7 (IC50=1.64nM).
价 格:¥电议型 号:T67737产 地:中国大陆
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T60063Fluorogen binding modulator-1;化合物 Fluorogen binding modulator-1Fluorogen binding modulator-1;Fluorog
Fluorogen binding modulator-1 (Fluorogen binding modulator-1) is a nonfluorescent inhibitors of Fluorogen–Fluorogen Activating Protein Binding Pairn.
价 格:¥电议型 号:T60063产 地:中国大陆
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T40361Integrin Binding Peptide;Integrin Binding PeptideIntegrin Binding Peptide
Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.
价 格:¥电议型 号:T40361产 地:中国大陆
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T37473SBFI AM;SBFI AMSodium-binding Benzofuran Isophthalate Acetoxymethyl ester;Sodium-binding Benzofuran
SBFI AM is a membrane-permeant, fluorescent Na+ indicator dye. It is selective for Na+ over K+ with Kd values of 20 and 120 mM for these ions, respectively. [1]Increasing concentration of Na+ increases the ratio of excitation efficiency at 330-345 nm to that at 370-390 nm with emission collected at 450-550 nm. [1] Therefore, ratio fluorometry and imaging can be performed with the same wavelengths. SBF AM is suitable for single intracellular dye injection and is typically used for high-resolutio
价 格:¥电议型 号:T37473产 地:中国大陆
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T19172A-1210477-piperazinyl;化合物 T19172PROTAC Mcl1-binding moiety 1;PROTAC Mcl1-binding moiety 1
A-1210477-piperazinyl is a compound that specifically targets and binds to the protein myeloid cell leukemia 1 (MCL1). This compound is utilized in PROTAC technology, which harnesses the ability to selectively degrade target proteins.
价 格:¥电议型 号:T19172产 地:中国大陆
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T18641SirReal1-O-propargyl;化合物 T18641PROTAC Sirt2-binding moiety 1;PROTAC Sirt2-binding moiety 1
SirReal1-O-propargyl, a moiety based on SirReal1, is a selective and highly potent inhibitor of Sirtuin 2 (Sirt2), demonstrating an IC50 of 2.4 μM. It operates by binding to the cereblon ligand through a linker, facilitating the formation of PROTAC for the degradation of Sirt2[1].
价 格:¥电议型 号:T18641产 地:中国大陆
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T18613MV-1-NH-Me;化合物 T18613PROTAC IAP binding moiety 2;PROTAC IAP binding moiety 2
MV-1-NH-Me, an MV-1-derived IAP ligand, connects to an ABL inhibitor through a linker, resulting in the formation of SNIPER[1].
价 格:¥电议型 号:T18613产 地:中国大陆
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T18612Bestatin-amido-Me;化合物 T18612PROTAC IAP binding moiety 1;PROTAC IAP binding moiety 1
Bestatin-amido-Me, a derivative of Bestatin, acts as an IAP ligand and interacts with ABL inhibitor through a linker to produce SNIPER[1].
价 格:¥电议型 号:T18612产 地:中国大陆
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T18611AP1867-2-(carboxymethoxy);化合物 T18611PROTAC FKBP12-binding moiety 2;PROTAC FKBP12-binding moiety 2
AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].
价 格:¥电议型 号:T18611产 地:中国大陆
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T18601Desmethyl-QCA276;化合物 T18601PROTAC BRD4-binding moiety 4;PROTAC BRD4-binding moiety 4
Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].
价 格:¥电议型 号:T18601产 地:中国大陆
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T18599PROTAC BRD4-binding moiety 1;化合物 T18599PROTAC BRD4-binding moiety 1
PROTAC BRD4-binding moiety 1 is a BRD4 ligand that binds to the cereblon ligand through a linker, enabling the formation of a PROTAC complex. This complex efficiently degrades BRD4[1].
价 格:¥电议型 号:T18599产 地:中国大陆