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T798839-Chloromethyl-10-hydroxy-11-F-Camptothecin;化合物 9-Chloromethyl-10-hydroxy-11-F-Camptothecin9-Chlorom
9-Chloromethyl-10-hydroxy-11-F-Camptothecin, a novel derivative of camptothecin, functions as a DNA topoisomerase I (Topo I) inhibitor with potential applications in anticancer research [1].
价 格:¥电议型 号:T79883产 地:中国大陆
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T778207-Aminomethyl-10-methyl-11-fluoro camptothecin;化合物 7-Aminomethyl-10-methyl-11-fluoro camptothecin7-A
7-Aminomethyl-10-methyl-11-fluoro camptothecin, serving as a cytotoxic component of the antibody-drug conjugate (ADC) MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin, is employed in the synthesis of camptothecin ADCs [1].
价 格:¥电议型 号:T77820产 地:中国大陆
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T77701FL118;化合物FL118FL 118|||FL-118|||10,11-(Methylenedioxy)-20(S)-camptothecin;FL 118|||FL-118|||10,11-(M
FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway, thereby inhibiting migration and invasion of human breast cancer cells.
价 格:¥电议型 号:T77701产 地:中国大陆
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T75134MC-GGFG-AM-(10Me-11F-Camptothecin);化合物 MC-GGFG-AM-(10Me-11F-Camptothecin)MC-GGFG-AM-(10Me-11F-Campto
MC-GGFG-AM-(10Me-11F-Camptothecin) acts as a linker-payload conjugate in the synthesis of ZW251, an antibody-drug conjugate (ADC) designed to target human GPC3. This ADC comprises a humanized IgG1 antibody attached to ZD06519, a novel camptothecin-based topoisomerase 1 inhibitor, through a maleimide-anchor and a cleavable glycyl glycyl phenylalanyl glycine (GGFG)-aminomethyl (AM) linker. ZW251 exhibits strong affinity for GPC3 in both human and cynomolgus monkey cells. It is characterized by rap
价 格:¥电议型 号:T75134产 地:中国大陆
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T60123Chimmitecan;吉米替康(S)-9-Allyl-10-hydroxycamptothecin;(S)-9-Allyl-10-hydroxycamptothecin|||吉米替康
Chimmitecan ((S)-9-Allyl-10-hydroxycamptothecin) is a potent inhibitor of topoisomerase I and displays outstanding activity in vitro and in vivo.
价 格:¥电议型 号:T60123产 地:中国大陆
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T5S19529-Methoxycamptothecin;9-甲氧基喜树碱9-Methoxycamptothecin
9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.
价 格:¥电议型 号:T5S1952产 地:中国大陆
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T5853Rubitecan;鲁比特康RFS 2000|||9-Nitrocamptothecin;RFS 2000|||鲁比特康|||9-Nitrocamptothecin
Rubitecan (9-Nitrocamptothecin) is a DNA topoisomerase I inhibitor. It inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay in a concentration-dependent manner.Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties.
价 格:¥电议型 号:T5853产 地:中国大陆
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T4S195110-Methoxycamptothecin;10-甲氧基喜树碱10-Methoxycamptothecin
10-Methoxycamptothecin is a natural bioactive derivative of camptothecin (CPT) isolated from Camptotheca acuminata and possesses high anti-cancer properties.
价 格:¥电议型 号:T4S1951产 地:中国大陆
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T49529-Hydroxycamptothecin;9-羟基喜树碱9-HCPT|||10-Hydroxycampothecin;9-HCPT|||9-羟基喜树碱|||10-Hydroxycampothecin
9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.
价 格:¥电议型 号:T4952产 地:中国大陆
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T40179Sodium Camptothecin;喜树碱钠盐Sodium Camptothecin
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA.
价 格:¥电议型 号:T40179产 地:中国大陆
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T40049MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin;MC-AAA-NHCH2OCH2COO-7-aminomethyl
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), is a camptothecin payload which can be utilized in the synthesis of a camptothecin antibody-drug conjugate (ADC) by conjugation to a monoclonal antibody (mAb).
价 格:¥电议型 号:T40049产 地:中国大陆
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T3S19579-amino-CPT;9-氨基喜树碱Aminocamptothecin|||9-amino-2(S)-camptothecin|||9-Aminocamptothecin;9-氨基喜树碱|||Ami
9-amino-CPT (Aminocamptothecin) is an inhibitor of topoisomerase I with potent anticancer activity.
价 格:¥电议型 号:T3S1957产 地:中国大陆
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T3S19557-Ethylcamptothecin;7-乙基喜树碱7-Ethylcamptothecin
1. 7-Ethylcamptothecin has the superior antitumor activity than CPT. (a). 7-Ethylcamptothecin has a stronger growth-inhibiting activity against tumor cells. (b). 7-Ethylcamptothecin remains in the intestinal tract for a longer time and in higher amounts when administered in vivo.
价 格:¥电议型 号:T3S1955产 地:中国大陆
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T2764(S)-10-Hydroxycamptothecin;10-羟基喜树碱10-Hydroxycamptothecin|||10-HCPT;10-羟喜树碱|||10-羟基喜树碱|||10-Hydroxyc
(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
价 格:¥电议型 号:T2764产 地:中国大陆
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T27113Camptothecin-20(S)-O-propionate;化合物 T27113CZ 48|||CZ48|||CZ-48;CZ 48|||CZ48|||CZ-48
CZ-48 is a DNA topoisomerase inhibitor.
价 格:¥电议型 号:T27113产 地:中国大陆
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T24610Pegamotecan;化合物PegamotecanProthecan|||PEG-camptothecin|||PEG-beta-CPT;Prothecan|||PEG-camptothecin||
Pegamotecan (PEG-camptothecin) is a topoisomerase I (TOP1) inhibitor with anticancer activity, and it is used in the treatment of esophageal, non-small cell lung and pancreatic cancers.
价 格:¥电议型 号:T24610产 地:中国大陆
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T1521(±)-10-Hydroxycamptothecin;10-羟基喜树碱Hydroxy Camptothecine|||10-Hydroxycamptothecin;Hydroxy Camptothec
(±)-10-Hydroxycamptothecin (Hydroxy Camptothecine) is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
价 格:¥电议型 号:T1521产 地:中国大陆
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T1123Camptothecin喜树碱NSC-100880|||Campathecin|||喜树碱|||(S)-(+)-Camptothecin|||CPT
Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity. Camptothecin has antitumor activity and induces apoptosis.
价 格:¥电议型 号:T1123产 地:中国大陆
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T0486LIrinotecan Hydrochloride;伊立替康盐酸盐Camptothecin 11 hydrochloride|||CPT-11 hydrochloride;盐酸伊立替康|||伊立替康盐酸
Irinotecan Hydrochloride (CPT-11 hydrochloride) is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptothecin (SN-38) by a carboxylesterase-converting enzyme. One thousand-fold more potent than its parent compound irinotecan, SN-38 inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks that inhibit DNA replicat
价 格:¥电议型 号:T0486L产 地:中国大陆