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T5S1026Apigenin-7-glucuronideApigenin-7-glucuronide,Apigenin 7-O-glucuronide,
Apigenin-7-glucuronide possesses multiple activities, including antioxidant, anti-inflammatory, and aldose reductase inhibitory activities, it can inhibit MMP activities (IC50s: 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively).
价 格:¥电议型 号:T5S1026产 地:美洲
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T83873Dabigatran Acyl-β-D-Glucuronide TFA;化合物 Dabigatran Acyl-β-D-Glucuronide TFADabigatran β-1-O-Acyl Glu
Dabigatran acyl-β-D-glucuronide, an active metabolite of the thrombin inhibitor dabigatran, is synthesized predominantly through the action of the UDP-glucuronosyltransferase isoform UGT2B15. This compound, at a concentration of 0.46 ?M, effectively prolongs activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma.
价 格:¥电议型 号:T83873产 地:中国大陆
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T833035,7,8-Trihydroxy-6-methoxy flavone-7-O-glucuronideb;化合物 5,7,8-Trihydroxy-6-methoxy flavone-7-O-glucu
5,7,8-Trihydroxy-6-methoxyflavone-7-O-glucuronide is a naturally occurring compound extractable from Scutellaria baicalensis Georgi [1].
价 格:¥电议型 号:T83303产 地:中国大陆
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T82599DDC 3′-O-β-D glucuronide;化合物 DDC 3′-O-β-D glucuronideDDC 3′-O-β-D glucuronide
Compound 5, DDC 3′-O-β-D-glucuronide, is a drug metabolite with properties that inhibit the fibrillization and oligomerization of Aβ42, suggesting its potential utility in Alzheimer´s disease research [1].
价 格:¥电议型 号:T82599产 地:中国大陆
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T82026Isoscutellarein 8-O-β-D-glucuronide;化合物 Isoscutellarein 8-O-β-D-glucuronideIsoscutellarein 8-O-β-D-g
Isoscutellarein 8-O-β-D-glucuronide, a flavonoid antioxidant, can be isolated from the seeds of Theobroma grandiflorum [1] [2].
价 格:¥电议型 号:T82026产 地:中国大陆
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T81835MC-betaglucuronide-MMAE-2;化合物 MC-betaglucuronide-MMAE-2MC-betaglucuronide-MMAE-2
MC-betaglucuronide-MMAE-2 is an ADC (antibody-drug conjugate) agent-linker conjugate that exhibits potent antitumor activity; it consists of MMAE (a tubulin polymerization inhibitor) connected through the cleavable linker MC-betaglucuronide.
价 格:¥电议型 号:T81835产 地:中国大陆
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T81597Oroxylin A 7-O-β-D-glucuronide methyl ester;化合物 Oroxylin A 7-O-β-D-glucuronide methyl esterOroxylin
Oroxylin A 7-O-β-D-glucuronide methyl ester, a natural product, can be isolated from the roots of Scutellaria baicalensis Georgi [1].
价 格:¥电议型 号:T81597产 地:中国大陆
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T81540Parthenosin;化合物 ParthenosinQuercetin 3-O-β-D-glucuronide butyl ester;Quercetin 3-O-β-D-glucuronide b
Parthenosin (Quercetin 3-O-β-D-glucuronide butyl ester), a flavonoid derived from the aerial parts of Calligoum polygonoides, exhibits cytotoxic properties with IC50 values of 60.46 μg/mL for HepG2 and 61.4 μg/mL for MCF-7 cell lines [1].
价 格:¥电议型 号:T81540产 地:中国大陆
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T80692β-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE;化合物 β-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAEβ-Glu
β-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE (compound 20), an auristatins-glucuronide conjugate, exhibits in vitro antiproliferative effects on cancer cells, both β-glucuronidase pretreated and untreated, with an IC50 range of 5.7 nM to 9.7 nM. Demonstrating powerful antitumor efficacy in an HCT-116 xenograft mouse model, this compound does not induce side effects [1].
价 格:¥电议型 号:T80692产 地:中国大陆
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T80658Quercetin 7-glucuronide;化合物 Quercetin 7-glucuronideQuercetin 7-O-β-glucuronide;Quercetin 7-O-β-glucu
Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a Quercetin metabolite found in Madagascarian Uncarina species, has the capability to inhibit LDL oxidation [1].
价 格:¥电议型 号:T80658产 地:中国大陆
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T78519Curcumin-β-D-glucuronide;化合物 Curcumin-β-D-glucuronideCurcumin-β-D-glucuronide
Curcumin-β-D-glucuronide, a principal metabolite detected in hepatic tissue and portal blood following oral consumption of Curcumin, is utilized in colon cancer research [1] [2].
价 格:¥电议型 号:T78519产 地:中国大陆
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T78136Perindopril acyl-β-D-glucuronide;培哚普利酰基-β-D-葡糖苷酸Perindopril acyl-β-D-glucuronide
Perindopril acyl-β-D-glucuronide is a metabolite of the ACE inhibitor perindopril [1].
价 格:¥电议型 号:T78136产 地:中国大陆
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T75363Fluorescein Di-β-D-Glucuronide;化合物 Fluorescein Di-β-D-GlucuronideFluorescein Di-β-D-Glucuronide
Fluorescein Di-β-D-Glucuronide, a fluorescent probe, enables non-invasive imaging of intestinal bacterial β-glucuronidase activity in nude mice. This compound´s utilization for both in vitro and in vivo imaging offers valuable insights into bacterial β-glucuronidase activity, thereby enhancing pharmacodynamic research on its specific inhibitors in animal models [1].
价 格:¥电议型 号:T75363产 地:中国大陆
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T74438β-Glucuronide-dPBD-PEG5-NH2 TFA;化合物 β-Glucuronide-dPBD-PEG5-NH2 TFAβ-Glucuronide-dPBD-PEG5-NH2 TFA
β-Glucuronide-dPBD-PEG5-NH2 TFA is a β-glucuronide-linked pyrrolobenzodiazepine dimer employed in the synthesis of the antibody-drug conjugate (ADC) cIRCR201-dPBD, utilizing a cleavable β-glucuronide linkage. Serving as a proagent, it aims to mitigate side effects, inducing apoptosis and arresting the cell cycle, thereby exhibiting antitumor activity [1].
价 格:¥电议型 号:T74438产 地:中国大陆
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T74437β-Glucuronide-dPBD-PEG5-NH2;化合物 β-Glucuronide-dPBD-PEG5-NH2β-Glucuronide-dPBD-PEG5-NH2
β-Glucuronide-dPBD-PEG5-NH2 is a β-glucuronide-linked pyrrolobenzodiazepine dimer that functions as a proagent for the synthesis of the antibody-drug conjugate (ADC) cIRCR201-dPBD, utilizing a cleavable β-glucuronide linkage. This compound targets and binds to the prenylated antibody, facilitating the controlled release of the drug and thereby mitigating side effects. Furthermore, β-Glucuronide-dPBD-PEG5-NH2 exhibits antitumor properties by inducing apoptosis and arresting the cell cycle [1].
价 格:¥电议型 号:T74437产 地:中国大陆
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T74279Curcumin monoglucuronide;化合物 Curcumin monoglucuronideCurcumin monoglucuronide
Curcumin monoglucuronide, a glucuronic acid conjugate and in vivo metabolite of curcumin, is utilized in the study of curcumin´s metabolism and the exploration of its pharmaceutical development. It holds promise for cancer research[1].
价 格:¥电议型 号:T74279产 地:中国大陆
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T73905SN-38 glucuronide;化合物 SN-38 glucuronideSN-38 glucuronide
SN-38 glucuronide, an inactive metabolite of Irinotecan, serves as a derivative of this cancer-fighting agent. Irinotecan, known for inhibiting topoisomerase I, is utilized in the research of colon and rectal cancer [1].
价 格:¥电议型 号:T73905产 地:中国大陆
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T73765Estrone 3-glucuronide;化合物 Estrone 3-glucuronideEstrone 3-glucuronide
Estrone 3-glucuronide, a deuterium-labeled version, is recognized as the primary metabolite of estradiol and serves as a urinary marker for predicting the fertile window [1].
价 格:¥电议型 号:T73765产 地:中国大陆
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T73761Estriol 16α-(β-D-glucuronide);化合物 Estriol 16α-(β-D-glucuronide)Estriol 16α-(β-D-glucuronide)
Estriol 16α-(β-D-glucuronide), an endogenous metabolite found in urine, is utilized in pregnancy research [1] [2].
价 格:¥电议型 号:T73761产 地:中国大陆
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T71983Zidovudine glucuronide;化合物 Zidovudine glucuronideZidovudine glucuronide
Zidovudine glucuronide is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming.
价 格:¥电议型 号:T71983产 地:中国大陆