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  • T74955hCAIX-IN-13;化合物 hCAIX-IN-13hCAIX-IN-13

    hCAIX-IN-13 (Pt2), a Carbonic Anhydrase IX (CAIX) inhibitor, demonstrates a notable IC50 value of 6.57 μM, efficiently impeding cancer cell growth and promoting apoptosis. It is valuable for cancer research [1].

    价 格:¥电议型 号:T74955产 地:中国大陆

  • T7460α-Cyano-4-hydroxycinnamic acid;2-氰基-4-羟基α-Cyano-4-hydroxycinnamic acid(α-CHCA);α-Cyano-4-hydroxycinn

    α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate transport in rat heart mitochondria (IC50 : 1.5 μM).

    价 格:¥电议型 号:T7460产 地:中国大陆

  • T74486hCAIX-IN-17;化合物 hCAIX-IN-17hCAIX-IN-17

    Compound 6f, also known as hCA IX-IN-1, is a human carbonic anhydrase (hCA) inhibitor that exhibits varying inhibitory effectiveness across different hCA isoforms, with K i values of 331.4 nM for hCA I, 28.4 nM for hCA II, 9.4 nM for hCA IX, and 17.8 nM for hCA XII. It is notable for its anticancer activity [1].

    价 格:¥电议型 号:T74486产 地:中国大陆

  • T74331hCAII-IN-7;化合物 hCAII-IN-7hCAII-IN-7

    Compound R-13, also known as hCAII-IN-7, is a powerful inhibitor of human carbonic anhydrase (hCA), exhibiting inhibition constants (Ki) of 60.7 nM for hCA I, 320.7 nM for hCA II, 2298 nM for hCA IV, and 35.2 nM for hCA IX, respectively [1].

    价 格:¥电议型 号:T74331产 地:中国大陆

  • T74330hCAII-IN-6;化合物 hCAII-IN-6hCAII-IN-6

    hCAII-IN-6 (Compound S-13), a potent inhibitor of human carbonic anhydrase II (hCA II) with a K i of 4.4 nM, also exhibits inhibitory activity against other hCA isoforms, namely I, IV, and IX, with K i values of 9.2 nM, 480.2 nM, and 14.7 nM, respectively. It is utilized in glaucoma research [1].

    价 格:¥电议型 号:T74330产 地:中国大陆

  • T73177hCAII-IN-9;化合物hCAII-IN-9hCAII-IN-9

    hCAII-IN-9 is a potent carbonic anhydrase inhibitor that inhibits hCA II, hCA IX, and hCA XII with IC50s of 1.18 μM and 0.17 μM , and 2.99 μM , respectively. hCAII-IN-9 is not blood-brain barrier permeable.

    价 格:¥电议型 号:T73177产 地:中国大陆

  • T73036hCA IX-IN-2;化合物 hCA IX-IN-2hCA IX-IN-2

    hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferative activity.

    价 格:¥电议型 号:T73036产 地:中国大陆

  • T73030hCAIX-IN-14;化合物 hCAIX-IN-14hCAIX-IN-14

    hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM [1] .

    价 格:¥电议型 号:T73030产 地:中国大陆

  • T73029hCAIX-IN-15;化合物 hCAIX-IN-15hCAIX-IN-15

    hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer activity suitable for cancer research [1].

    价 格:¥电议型 号:T73029产 地:中国大陆

  • T73028hCAIX-IN-16;化合物 hCAIX-IN-16hCAIX-IN-16

    hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII. It can arrest the cell cycle in the G0-G1 and S phases and induce apoptosis in MDA-MB-468 breast cancer cells. Demonstrating broad-spectrum anticancer activity, hCAIX-IN-16 is a potential tool for cancer research [1].

    价 格:¥电议型 号:T73028产 地:中国大陆

  • T72840hCAIX/XII-IN-6;化合物 hCAIX/XII-IN-6hCAIX/XII-IN-6

    hCAIX/XII-IN-6, an orally active carbonic anhydrase (CA) inhibitor, targets human CA isoforms hCA I, II, IV, IX, and XII with inhibition constants (K i) of 6697 nM, 2950 nM, 4093 nM, 4.1 nM, and 7.7 nM, respectively. This compound is utilized in rheumatoid arthritis (RA) research.

    价 格:¥电议型 号:T72840产 地:中国大陆

  • T72283(+)-Dihydrocalanolide A;化合物 (+)-Dihydrocalanolide ANSC 678323|||DHCal A ; NSC 678323|||DHCal A;NSC

    (+)-Dihydrocalanolide A (DHCal A; NSC 678323), an orally active nonnucleoside inhibitor of reverse transcriptase, is utilized in research related to HIV infection.

    价 格:¥电议型 号:T72283产 地:中国大陆

  • T64102hCAI/II-IN-5;化合物 hCAI/II-IN-5hCAI/II-IN-5

    hCAI/II-IN-5 is a potent inhibitor of hCA I and hCA II (human carbonic anhydrase isozymes I and II), with IC50 values of 37.88 and 45.23 nM, respectively. hCAI/II-IN-5 also inhibits α-Glycosidase (IC50: 48.98 nM) and AChE (IC50: 420.14 nM). nM). hCAI/II-IN-5 can be used in the study of diabetes, heart failure, Alzheimer´s disease, ulcers, epilepsy and many other diseases.

    价 格:¥电议型 号:T64102产 地:中国大陆

  • T63973hCAXII-IN-3;化合物 hCAXII-IN-3hCAXII-IN-3

    hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).

    价 格:¥电议型 号:T63973产 地:中国大陆

  • T63972hCA I-IN-2;化合物 hCA I-IN-2hCA I-IN-2

    hCA I-IN-2 (Compound 6d) is a selective inhibitor of human carbonic anhydrase I (hCA I) and acts on hCA I (Ki: 18.8 nM), hCA II (Ki: 375.1 nM), hCAIX (Ki: 1721 nM) and hCAXII (Ki: 283.9 nM).

    价 格:¥电议型 号:T63972产 地:中国大陆

  • T63908hCAII-IN-4;化合物 hCAII-IN-4hCAII-IN-4

    hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM. Additionally, it demonstrates inhibition of β-glucuronidase, presenting an IC50 value of 773.9 μM [1].

    价 格:¥电议型 号:T63908产 地:中国大陆

  • T63805β-Glucuronidase/hCAII-IN-1;化合物 β-Glucuronidase/hCAII-IN-1β-Glucuronidase/hCAII-IN-1

    β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50 values of 440.1 μM and 4.91 μM, respectively [1].

    价 格:¥电议型 号:T63805产 地:中国大陆

  • T63789β-Glucuronidase/hCAII-IN-2;化合物 β-Glucuronidase/hCAII-IN-2β-Glucuronidase/hCAII-IN-2

    β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.

    价 格:¥电议型 号:T63789产 地:中国大陆

  • T63764hCA XII/II/IX-IN-1;化合物 hCA XII/II/IX-IN-1hCA XII/II/IX-IN-1

    hCA XII/II/IX-IN-1 is a potent inhibitor of human carbonic anhydrase (hCA) and is able to act on hCA I (IC50: 2.6 μM), hCA II (IC50: 0.004 μM), hCA IX (IC50: 0.005 μM) and hCA XII (IC50: 0.001 μM). hCA XII/II/IX -IN-1 exhibited anticancer effects.

    价 格:¥电议型 号:T63764产 地:中国大陆

  • T63753hCAIX-IN-3;化合物 hCAIX-IN-3hCAIX-IN-3

    hCAII-IN-3 (compound 7e) is a selective and potent carbonic anhydrase (CA II/IX) inhibitors with their Kis values of 124.2 and 30.5 nM, respectively. hCAII-IN-1 has shown investigational potential for cancer disease.

    价 格:¥电议型 号:T63753产 地:中国大陆

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