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T72636BRD4 Inhibitor-26；化合物 BRD4 Inhibitor-26BRD4 Inhibitor-26
BRD4 Inhibitor-26, a bromodomain protein 4 (BRD4) inhibitor/nitric oxide-donator, exhibits inhibitory activity against BRD4 (BD1) and BRD4 (BD2) with IC50 values of 0.82 μM and 1.94 μM, respectively. It is utilized in ovarian cancer research.
价 格：￥电议型 号：T72636产 地：中国大陆
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T72630BRD4 Inhibitor-25；化合物 BRD4 Inhibitor-25BRD4 Inhibitor-25
BRD4 Inhibitor-25, a chemical compound targeting the BD1 and BD2 domains of BRD4 with half-maximal inhibitory concentrations (IC50s) of 0.82 μM and 1.94 μM respectively, demonstrates efficacy in inducing apoptotic and autophagic cell death in ovarian cancer cells. This compound is utilized in researching cancers, cardiovascular, neuromuscular, and inflammatory disorders.
价 格：￥电议型 号：T72630产 地：中国大陆
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T72547Plm IV inhibitor-2；化合物 Plm IV inhibitor-2Plm IV inhibitor-2
Plm IV Inhibitor-2 is a powerful inhibitor of digestive vacuole plasmepsins IV (Plm IV), displaying IC50 values of 24 nM for Plm IV, 70 nM for Plm II, and 0.3 μM for Plm I. It is used in malaria research involving Plasmodium parasites.
价 格：￥电议型 号：T72547产 地：中国大陆
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T72135(1s,4s)-Menin-MLL inhibitor-23；化合物 (1s,4s)-Menin-MLL inhibitor-23(1s,4s)-Menin-MLL inhibitor-23
(1s,4s)-Menin-MLL Inhibitor-23, an enantiomer of Menin-MLL Inhibitor-23 (Example 99A), functions as an inhibitor of the menin-MLL interaction [1].
价 格：￥电议型 号：T72135产 地：中国大陆
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T68498UCK2 Inhibitor-2；化合物 UCK2-IN-20874830UCK2 Inhibitor-2
UCK2 Inhibitor-2, a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2), exhibits an IC50 of 3.8 ?M and effectively suppresses uridine salvage within cells.
价 格：￥电议型 号：T68498产 地：中国大陆
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T64009HIV-1 inhibitor-23；化合物 HIV-1 inhibitor-23HIV-1 inhibitor-23
HIV-1 inhibitor-23 is a highly potent inhibitor of HIV-1 non-nucleoside reverse transcriptase, acting on both wild-type HIV-1 (EC50: 24.9 nM) and mutant strain K103N (EC50: 10.4 nM). microsomal stability in vitro.
价 格：￥电议型 号：T64009产 地：中国大陆
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T63962HIV-1 inhibitor-29；化合物 HIV-1 inhibitor-29HIV-1 inhibitor-29
HIV-1 inhibitor-29 is a potent inhibitor of HIV-1 and acts against HIV-1 IIIB (EC50: 2.18 μM). HIV-1 inhibitor-29 shows high resistance to the F227L/V106A strain with an EC50 value of 0.974 μM. HIV-1 inhibitor-29 showed low cytotoxicity against MT-4 cells with a CC50 value of 211 μM. HIV-1 inhibitor-29 can be used in AIDS research.
价 格：￥电议型 号：T63962产 地：中国大陆
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T63928KRAS inhibitor-21；化合物 KRAS inhibitor-21KRAS inhibitor-21
KRAS inhibitor-21 (22b) is a KRAS G12C inhibitor (IC50<0.01 μM) that can be used in cancer research.
价 格：￥电议型 号：T63928产 地：中国大陆
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T63890HIV-1 inhibitor-22；化合物 HIV-1 inhibitor-22HIV-1 inhibitor-22
HIV-1 inhibitor-22 is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (RT) (HIV-1 RT: IC50=3.63 μM). M and also showed low cytotoxicity with a CC50 > 227 μM.
价 格：￥电议型 号：T63890产 地：中国大陆
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T63499HIV-1 inhibitor-28；化合物 HIV-1 inhibitor-28HIV-1 inhibitor-28
HIV-1 inhibitor-28 is a potent and selective HIV-1 inhibitor with EC50=58 nM for wild-type HIV-1, IC50=3.37 μM for wild-type HIV-1 reverse transcription, and relatively low toxicity to MT-4 cells with CC50= 38.6 μM. HIV-1 inhibitor-28 can be used in AIDS research.
价 格：￥电议型 号：T63499产 地：中国大陆
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T63391Calpain Inhibitor-2；化合物 Calpain Inhibitor-2Calpain Inhibitor-2
Calpain Inhibitor-2 is a lipophilic calpain inhibitor, and they showed moderate to good anti-proliferative effects in vitro compared to melanoma cell lines (A-375 and B-16F1) and PC-3 prostate cancer cells. was able to inhibit the invasion of 80% of DU-145 cells.
价 格：￥电议型 号：T63391产 地：中国大陆
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T63279ATM Inhibitor-2；化合物 ATM Inhibitor-2ATM Inhibitor-2
ATM Inhibitor -2 is a potent and selective inhibitor of ATM (IC50<1 nM).
价 格：￥电议型 号：T63279产 地：中国大陆
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T63113HIV-1 inhibitor-21；化合物 HIV-1 inhibitor-21HIV-1 inhibitor-21
HIV-1 inhibitor-21 (compound 9b) is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (RT) and acts on HIV-1 RT (IC50: 0.55 μM). HIV-1 inhibitor-21 inhibits both wild-type HIV-1 (EC50: 12.7 nM) and mutant virus strain K103N (EC50: 10.4 nM) with relatively low cytotoxicity (CC50 for MT-4: 10.2 μM).
价 格：￥电议型 号：T63113产 地：中国大陆
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T62965TDP1 Inhibitor-2；化合物 TDP1 Inhibitor-2TDP1 Inhibitor-2
TDP1 Inhibitor-2 is a potent inhibitor of TDP1 (tyrosyl-DNA phosphodiesterase 1) (IC50: 99 nM) and inhibits SCAN1 (spinal cerebellar ataxia syndrome with axonal neuropathy) (IC50: 3.5 μM).
价 格：￥电议型 号：T62965产 地：中国大陆
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T62883BRD4 Inhibitor-23；化合物 BRD4 Inhibitor-23BRD4 Inhibitor-23
BRD4 Inhibitor-23 is a potent, orally active BRD4 inhibitor that acts on BRD4 BD-1 (IC50: 6.21 nM) and BRD4 BD-2 (IC50: 1.44 nM).
价 格：￥电议型 号：T62883产 地：中国大陆
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T62431HIV-1 inhibitor-25；化合物 HIV-1 inhibitor-25HIV-1 inhibitor-25
HIV-1 inhibitor-25 (compound R-12a) is a potent inhibitor of HIV-1 reverse transcription (HIV-1 RT) (IC50: 0.1061 nM). HIV-1 inhibitor-25 exhibits a high antiviral effect against wild-type HIV-1 with an EC50 value of 13.6 nM and a low cytotoxicity (to MT). HIV-1 inhibitor-25 also inhibits HIV-1 mutants (L100I, K103 N, Y181C, Y188L, E138K, F227L+V106A) with EC50=0.1961 ~ 5.8136 μM. inhibitor-25 can be used to study AIDS.
价 格：￥电议型 号：T62431产 地：中国大陆
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T62430HIV-1 inhibitor-24；化合物 HIV-1 inhibitor-24HIV-1 inhibitor-24
HIV-1 inhibitor-24 (compound S-12a) is a potent inhibitor of HIV-1 reverse transcription (HIV-1 RT) (IC50: 9.5 nM). HIV-1 inhibitor-24 exhibits a high antiviral effect on wild-type HIV-1 with an EC50 value of 1.6 nM and low cytotoxicity (CC50 on MT-4 cells). HIV-1 inhibitor-24 was well tolerated in mice at a dose of 2 g/kg and had a significant cardiovascular safety profile.
价 格：￥电议型 号：T62430产 地：中国大陆
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T62079MEK4 inhibitor-2；化合物 MEK4 inhibitor-2MEK4 inhibitor-2
MEK4 Inhibitor-2, a novel MEK4 inhibitor, demonstrates efficacy against pancreatic adenocarcinoma, exhibiting an IC50 value of 83 nM.
价 格：￥电议型 号：T62079产 地：中国大陆
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T62010HIV-1 inhibitor-20；化合物 HIV-1 inhibitor-20HIV-1 inhibitor-20
HIV-1 inhibitor-20 is a potent HIV-1 inhibitor.
价 格：￥电议型 号：T62010产 地：中国大陆
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T61894sEH inhibitor-2；化合物 sEH inhibitor-2sEH inhibitor-2
SEH inhibitor-2 (compound 5l) is a soluble epoxide hydrolase (sEH) inhibitor with oral activity (IC50=0.9 nM), and the predicted oral absorption percentage is 71.2-88.4%. SEH inhibitor-2 can maintain a high concentration of eicosanoic acid (EETs) in serum. SEH inhibitor-2 has research value in cardiovascular protection.
价 格：￥电议型 号：T61894产 地：中国大陆
