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TP1882L1Orphanin FQ(1-11) acetate(178249-41-7 free base)Orphanin FQ(1 11) acetate(178249 41 7 free base),Orp
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice.
价 格:¥电议型 号:TP1882L1产 地:中国大陆
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T60032BRM/BRG1 ATP Inhibitor-2Epigenetic Reader Domain,Inhibitor,BRM/BRG1 ATP Inhibitor 2,inhibit,BRM/BRG1
BRM/BRG1 ATP Inhibitor-2 is an inhibitor of BRG1/BRM ATPase and can be used in studies about the treatment of BAF-related disorders.
价 格:¥电议型 号:T60032产 地:中国大陆
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T9743FEN1-IN-SC13FEN1 IN SC13,Inhibitor,FEN1INSC13,FEN-1-IN-SC13,inhibit
FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)
价 格:¥电议型 号:T9743产 地:中国大陆
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T8595Practololreceptor,inhibit,arrhythmias,β1-adrenergic,Practolol,Beta Receptor,Adrenergic Receptor,card
Practolol is a selective β-adrenoceptor blocker.
价 格:¥电议型 号:T8595产 地:中国大陆
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T8796CAN508inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,
CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 μM, respectively.CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.
价 格:¥电议型 号:T8796产 地:中国大陆
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T7741DS-1001binhibit,DS 1001b,Inhibitor,Isocitrate Dehydrogenase (IDH),DS-1001b,DS1001b
DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)
价 格:¥电议型 号:T7741产 地:中国大陆
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TQ0283RS102895CC chemokine receptor,CCR,Inhibitor,RS102895,inhibit,RS-102895,RS 102895
RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.
价 格:¥电议型 号:TQ0283产 地:中国大陆
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T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
价 格:¥电议型 号:T9041产 地:中国大陆
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T6908NSC 228155Epidermal growth factor receptor,Histone Acetyltransferase,EGFR,HER1,HATs,inhibit,Inhibito
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
价 格:¥电议型 号:T6908产 地:中国大陆
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T6924Riviciclib hydrochlorideinhibit,Inhibitor,Riviciclib,CDK,Riviciclib hydrochloride,Cyclin dependent k
P276-00 is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.
价 格:¥电议型 号:T6924产 地:中国大陆
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T6767TCS7010Aurora Kinase,inhibit,TCS 7010,Apoptosis,TCS-7010,TCS7010,Inhibitor
Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.
价 格:¥电议型 号:T6767产 地:中国大陆
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T6443Chloroprocaine hydrochlorideinhibit,Na,K-ATPase,Sodium potassium pump,Chloroprocaine,anesthetic,2-Ch
Chloroprocaine HCl is a local anesthetic during surgical procedures.
价 格:¥电议型 号:T6443产 地:中国大陆
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T7596FirocoxibLPS,COX-2,fever,ML1785713,Cyclooxygenase,COX,inhibit,Firocoxib,Inhibitor,anti-inflammatory,
Firocoxib is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.
价 格:¥电议型 号:T7596产 地:中国大陆
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T8222SelpercatinibFVB/NRj mice,RET (WT),inhibit,Inhibitor,RET (G810R),LOXO 292,LOXO292,RET (V804M),Selper
Selpercatinib is a tyrosine kinase inhibitor with antineoplastic properties(IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively)
价 格:¥电议型 号:T8222产 地:中国大陆
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T7083GLPG1837GLPG-1837,ABBV 974,Cystic fibrosis transmembrane conductance regulator,Inhibitor,CFTR,Autoph
GLPG1837 is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
价 格:¥电议型 号:T7083产 地:中国大陆
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T7974Lynestrenolinhibit,progesteronelike,Pregnane,Inhibitor,immunostimulatory,zfPXR,Lynestrenol,PXR,hPXR
Lynestrenol is a synthetic progestational hormone, is the progesterone receptor agonist
价 格:¥电议型 号:T7974产 地:中国大陆
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T6507Gabapentin hydrochlorideInhibitor,Gabapentin hydrochloride,Gabapentin,Calcium Channel,Ca channels,in
Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.
价 格:¥电议型 号:T6507产 地:中国大陆
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T38163ML-148ML-148,ML 148,selective,Inhibitor,prostaglandin-signaling,15-PGDH,15-Hydroxyprostaglandin dehy
ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostaglandin-signaling pathways.
价 格:¥电议型 号:T38163产 地:中国大陆
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T6648Rotundine5-hydroxytryptamine Receptor,Inhibitor,Dopamine Receptor,Rotundine,5-HT Receptor,inhibit,Se
Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.
价 格:¥电议型 号:T6648产 地:中国大陆
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T6874Lercanidipine hydrochlorideantihypertensive,Inhibitor,calcium,Lercanidipine,Lercanidipine hydrochlor
Lercanidipine is a calcium channel blocker of the dihydropyridine class.
价 格:¥电议型 号:T6874产 地:中国大陆