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T79926Poly(A) polymerase;化合物 Poly(A) polymerasePoly(A) polymerase
Poly(A) polymerase enzymatically adds a polyadenosine tail of 20-200 adenine bases to the 3´ end of RNA, a process that involves integrating ATP as AMP. This modification enhances RNA stability and augments mRNA translation efficiency in eukaryotic cells, evidencing the enzyme´s high tailing efficiency [1] [2].
价 格:¥电议型 号:T79926产 地:中国大陆
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T79923T7 RNA polymerase;T7 RNA聚合酶T7 RNA polymerase
T7 RNA polymerase, expressed by Escherichia coli from the T7 bacteriophage RNA polymerase gene, is a highly specific enzyme utilized for in vitro transcription (IVT) of mRNA. This polymerase requires Mg 2+ and selects only DNA templates that contain the T7 promoter sequence, whether single-stranded or double-stranded. It employs NTPs to synthesize RNA that is complementary to the single-stranded DNA following the promoter [1] [2].
价 格:¥电议型 号:T79923产 地:中国大陆
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T79922Taq DNA polymerase;化合物 Taq DNA polymeraseTaq DNA polymerase
Taq DNA polymerase is a thermostable enzyme utilized in polymerase chain reactions (PCR) to amplify DNA sequences [1].
价 格:¥电议型 号:T79922产 地:中国大陆
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T79308DNA polymerase-IN-3;化合物 DNA polymerase-IN-3DNA polymerase-IN-3
DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in proliferative disease research [1].
价 格:¥电议型 号:T79308产 地:中国大陆
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T79307DNA polymerase-IN-2;化合物 DNA polymerase-IN-2DNA polymerase-IN-2
DNA polymerase-IN-2 (Compd 3c), a coumarin derivative, demonstrates inhibitory activity towards Taq DNA polymerase, with an IC50 value of 48.25 μM, and holds potential for application in value-added disease research [1].
价 格:¥电议型 号:T79307产 地:中国大陆
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T74765Viral polymerase-IN-1 hydrochloride;化合物 Viral polymerase-IN-1 hydrochlorideViral polymerase-IN-1 hyd
Viral polymerase-IN-1 hydrochloride, a derivative of Gemcitabine, effectively inhibits influenza A and B virus infections, demonstrating IC90 values ranging from 11.4 to 15.9 μM, and possesses activity against SARS-CoV-2 infection. This compound acts by interfering with viral RNA replication/transcription within cells [1].
价 格:¥电议型 号:T74765产 地:中国大陆
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T74631RNA polymerase II-IN-2;化合物 RNA polymerase II-IN-2RNA polymerase II-IN-2
RNA polymerase II-IN-2 (compound 20iii), a potent inhibitor of RNA polymerase II (Pol II) with a K i value of 9.5 nM, demonstrates cytotoxicity against cancer cells, exhibiting toxicity levels 2 and 5 times higher than α-amanitin in CHO and HEK293 cells, respectively [1].
价 格:¥电议型 号:T74631产 地:中国大陆
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T74630RNA polymerase II-IN-1;化合物 RNA polymerase II-IN-1RNA polymerase II-IN-1
RNA polymerase II-IN-1 (compound 19iv), an amatoxin, selectively inhibits RNA polymerase II (Pol II) with an IC50 of 36.66 nM. It exhibits heightened cytotoxicity towards cancer cells and reduced toxicity in normal cells compared to α-Amanitin [1].
价 格:¥电议型 号:T74630产 地:中国大陆