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T17433Amino-PEG36-CONH-PEG36-acid；化合物 T17433Amino-PEG36-CONH-PEG36-acid
Amino-PEG36-CONH-PEG36-acid is a polyethylene glycol (PEG)-based linker with amino and carboxylic acid functionalities. It finds utility in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17433产 地：中国大陆
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T17423Amino-PEG24-CH2-Boc；化合物 T17423Amino-PEG24-CH2-Boc
Amino-PEG24-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17423产 地：中国大陆
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T17403Amino-PEG10-CH2-Boc；化合物 T17403Amino-PEG10-CH2-Boc
Amino-PEG10-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17403产 地：中国大陆
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T17393Amine-PEG-amine (MW 35000)；化合物 T17393Amine-PEG-amine (MW 35000)
Amine-PEG-amine (MW 35000), a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1].
价 格：￥电议型 号：T17393产 地：中国大陆
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T17383Ald-Ph-amido-PEG3-C-COOH；化合物 T17383Ald-Ph-amido-PEG3-C-COOH
Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker utilized in the formation of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T17383产 地：中国大陆
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T17373Ald-Ph-PEG12-TFP ester；化合物 T17373Ald-Ph-PEG12-TFP ester
Ald-Ph-PEG12-TFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17373产 地：中国大陆
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T17353Acid-PEG13-NHS ester；化合物 T17353Acid-PEG13-NHS ester
Acid-PEG13-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17353产 地：中国大陆
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T16881LSIB 1553A；化合物 SIB 1553ASIB 1553A
SIB 1553A is an orally available and selective agonist of nicotinic acetylcholine receptors (nAChRs), which are subtype-selective ligands for nicotinic acetylcholine receptors.SIB-1553A is a cognitive enhancer that may be used in the study of neurodegenerative-related diseases such as Alzheimer´s disease.
价 格：￥电议型 号：T16881L产 地：中国大陆
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T16881SIB-1553A hydrochloride；SIB-1553A 盐酸盐SIB-1553A hydrochloride
SIB-1553A hydrochloride is an orally available, selective nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand.SIB-1553A hydrochloride enhances cognition and may be useful in the study of Alzheimer´s disease and cognitive impairment.
价 格：￥电议型 号：T16881产 地：中国大陆
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T1688Pregnanediol；孕二醇5Beta-Pregnane-3Alpha,20alpha-Diol|||Pregnandiol；5Beta-Pregnane-3Alpha,20alpha-Diol|
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol(5Beta-Pregnane-3Alpha,20alpha-Diol) has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.
价 格：￥电议型 号：T1688产 地：中国大陆
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T16723Ranirestat；化合物 T16723AS-3201；AS-3201
Ranirestat effective and orally active aldose reductase inhibitor ( IC50s: 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively and a Ki: 0.38 nM for recombinant human AR). Ranirestat has a neuroprotective effect on diabetic retinas.
价 格：￥电议型 号：T16723产 地：中国大陆
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T16563Pozanicline；化合物 T16563ABT-089；ABT-089
Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at α4β2 nAChRs (Ki=16 nM). It shows high selectivity for α6β2 and α4α5β2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM .
价 格：￥电议型 号：T16563产 地：中国大陆
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T14993Rociletinib hydrobromide；化合物 T14993AVL-301 hydrobromide|||CO-1686 (hydrobromide)|||CNX-419 hydrobrom
Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).
价 格：￥电议型 号：T14993产 地：中国大陆
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T14886Cbz-B3A；化合物 Cbz-B3ACbz-B3A
Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%.
价 格：￥电议型 号：T14886产 地：中国大陆
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T14589Biotin-PEG3-acid化合物Biotin-PEG3-acid18-[(3AS,4S,6AR)-六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-基]-14-氧代-4,7,10-三氧杂-13
Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
价 格：￥电议型 号：T14589产 地：中国大陆
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T14483Azido-PEG9-Boc；化合物 T14483Azido-PEG9-Boc
Azido-PEG9-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14483产 地：中国大陆
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T14473Azido-PEG8-acid；化合物 T14473Azido-PEG8-acid
Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T14473产 地：中国大陆
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T14463Azido-PEG5-PFP ester；化合物 T14463Azido-PEG5-PFP ester
Azido-PEG5-PFP ester is a Polyethylene Glycol (PEG) and Alkyl/ether-based Proteolysis Targeting Chimera (PROTAC) linker, commonly employed for PROTAC synthesis [1].
价 格：￥电议型 号：T14463产 地：中国大陆
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T14453Azido-PEG4-Val-Cit-PAB-OH；化合物 T14453Azido-PEG4-Val-Cit-PAB-OH
Azido-PEG4-Val-Cit-PAB-OH is a 4-unit PEG ADC linker and a PEG-based PROTAC linker. It is employed for the synthesis of antibody-drug conjugates (ADCs)[1] and PROTACs[2].
价 格：￥电议型 号：T14453产 地：中国大陆
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T14443Azido-PEG4-beta-D-glucose；化合物 T14443Azido-PEG4-beta-D-glucose
Azido-PEG4-beta-D-glucose is a polyethylene glycol (PEG)-based linker compound essential for the efficient synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T14443产 地：中国大陆
