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T16680PTC-028
PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.
价 格:¥电议型 号:T16680产 地:中国大陆
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T1668Vinblastine sulfate硫酸长春碱;NSC49842;Vincaleukoblastine sulfate salt
Vinblastine sulfate can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).
价 格:¥电议型 号:T1668产 地:中国大陆
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T16512PFE-360PF-06685360
PFE-360 is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo).
价 格:¥电议型 号:T16512产 地:中国大陆
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T16282NemorexantDaridorexant;ACT-541468
Daridorexant is an effective orexin receptor antagonist. It also has IC50s of 2 nM and 3 nM for the Ox1 receptor and Ox2 receptor, respectively.
价 格:¥电议型 号:T16282产 地:中国大陆
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T16068MF-438
MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).
价 格:¥电议型 号:T16068产 地:中国大陆
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T1591Ancitabine hydrochloride盐酸环胞苷;Cyclocytidine hydrochloride;Cyclocytidine HCl;NSC 145668 HCl;Cyclo-CMP
Ancitabine Hydrochloride is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytarabine is converted to the triphosphate form within t
价 格:¥电议型 号:T1591产 地:中国大陆
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T1586TenoxicamMobiflex;Tenoxicamum;Ro-12-0068;Tilcotil;替诺昔康
Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
价 格:¥电议型 号:T1586产 地:中国大陆
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T1583VorinostatSAHA;suberoylanilide hydroxamic acid;MK0683;伏立诺他
Vorinostat is a pan-inhibitor of Histone Deacetylase with antineoplastic activity (IC50: ~10 nM).
价 格:¥电议型 号:T1583产 地:中国大陆
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T15686L-7416263-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole
L-741626 is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively).
价 格:¥电议型 号:T15686产 地:中国大陆
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T15681L-161982
L-161982 is a selective EP4 receptor antagonist. L-161982 decreases collagen-induced arthritis in mice. L-161982 fully blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells.
价 格:¥电议型 号:T15681产 地:中国大陆
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T1568AmoxapineCL-67772;阿莫沙平
Amoxapine exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve endings and blocks the response of dopamine receptors to dopamine. Amoxapine is a tricyclic antidepressant
价 格:¥电议型 号:T1568产 地:中国大陆
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T15568Imirestat咪瑞司他;Alcon 1576;AL 1576;HOE 843
Imirestat is an aldose reductase inhibitor that can be used in diabetes research.
价 格:¥电议型 号:T15568产 地:中国大陆
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T15454GW843682XGW843682
GW843682X is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s: 2.2 nM and 9.1 nM, respectively). It is also >100-fold selective against ~30 other kinases.
价 格:¥电议型 号:T15454产 地:中国大陆
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T15418GS-6201CVT-6883
GS-6201 is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM.
价 格:¥电议型 号:T15418产 地:中国大陆
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T15268FAAH-IN-2O-Desmorpholinopropyl Gefitinib;4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇
FAAH-IN-2 is a potent inhibitor of FAAH(fatty acid amide hydrolase).
价 格:¥电议型 号:T15268产 地:中国大陆
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T15201MAK683
MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).
价 格:¥电议型 号:T15201产 地:中国大陆
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T15053DarodipinePY-108068;PY 108-068;达罗地平
Darodipine is a dihydropyridine type Ca+2 antagonist.
价 格:¥电议型 号:T15053产 地:中国大陆
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T14968Cinanserin hydrochlorideSQ 10643
Cinanserin hydrochloride is a high affinity antagonist of the 5-HT2 receptor (Ki: 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus.
价 格:¥电议型 号:T14968产 地:中国大陆
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T1471Duloxetine hydrochlorideLY-248686 HCl;(S)-Duloxetine hydrochloride;LY-248686 hydrochloride;Duloxetin
Duloxetine hydrochloride is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and is also used for the treatment of pain in patients with DIABETES ME
价 格:¥电议型 号:T1471产 地:中国大陆
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T14687DeucravacitinibBMS-986165
BMS-986165 inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) a
价 格:¥电议型 号:T14687产 地:中国大陆