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T13017STL127705Compound L;7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimid
STL127705 is a potent Ku 70/80 heterodimer protein inhibitor and inhibits Ku70/80-DNA interaction with IC50 of 3.5 μM. STL127705 inhibits the activation of Ku-dependent DNA-PKCS kinase with IC50 of 2.5 μM.
价 格:¥电议型 号:T13017产 地:中国大陆
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T12877LSeltorexantJNJ-42847922
Seltorexant crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human and rat OX2R).
价 格:¥电议型 号:T12877L产 地:中国大陆
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T12853SBI-477
SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA. SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes.
价 格:¥电议型 号:T12853产 地:中国大陆
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T12774RSV-IN-1
RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.
价 格:¥电议型 号:T12774产 地:中国大陆
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T12773RS102895 hydrochlorideRS102895盐酸盐
RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).
价 格:¥电议型 号:T12773产 地:中国大陆
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T1277Lincomycin hydrochlorideLincomycin HCl;NSC 70731;U10149A;盐酸林可霉素
Lincomycin Hydrochloride Anhydrous is the anhydrous hydrochloride salt form of lincomycin, a lincosamide antibiotic originally identified in actinomycete Streptomyces lincolnensis with activity against gram-positive cocci and anaerobic bacteria.
价 格:¥电议型 号:T1277产 地:中国大陆
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T1258NabumetoneBRL14777;萘丁美酮
Nabumetone(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.
价 格:¥电议型 号:T1258产 地:中国大陆
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T12477Uzansertib phosphateINCB053914 phosphate
INCB053914 phosphate is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively).
价 格:¥电议型 号:T12477产 地:中国大陆
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T12277NVS-ZP7-4
NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).
价 格:¥电议型 号:T12277产 地:中国大陆
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T12177Natalizumab
Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn´s disease.
价 格:¥电议型 号:T12177产 地:中国大陆
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T12077ML303
ML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM).
价 格:¥电议型 号:T12077产 地:中国大陆
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T11933MAC13772
MAC13772 is a potent inhibitor of the enzyme BioA with an IC50 of 250 nM thereby inhibiting biotin biosynthesis. MAC13772 exhibits antibacterial activity.
价 格:¥电议型 号:T11933产 地:中国大陆
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T1193Clomiphene citrate枸橼酸氯米芬;NSC 35770;Clomifene citrate
Clomifene Citrate is a selective estrogen receptor modulator.
价 格:¥电议型 号:T1193产 地:中国大陆
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T11877LR-90
LR-90 is also used in the research of diabetic animal model.LR-90 is an advanced glycation end product (AGE) inhibitor, inhibits inflammatory responses in human monocytes.?
价 格:¥电议型 号:T11877产 地:中国大陆
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T11826LCH-7749944GNF-PF-2356
LCH-7749944 effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor with an IC50 of 14.93 μM.
价 格:¥电议型 号:T11826产 地:中国大陆
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T11766LEltanexorKPT-8602;ONO-7706;ATG-016
Eltanexor is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leuk
价 格:¥电议型 号:T11766L产 地:中国大陆
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T11447GNF4877
GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6 nM and 16 nM). It leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation cells.
价 格:¥电议型 号:T11447产 地:中国大陆
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T11277FG 7142ZK 39106;LSU-65
FG 7142 also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benz
价 格:¥电议型 号:T11277产 地:中国大陆
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T1124Flumethasone氟米松;NSC-54702;RS-2177;Flumetasone
Flumethasone is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
价 格:¥电议型 号:T1124产 地:中国大陆
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T11177ElinogrelPRT060128
Elinogrel can be given orally and intravenously and has a strong anti-platelet effect.Elinogrel is an effective, direct acting, competitive, reversible platelet P2Y12 antagonist (IC50=20 nM).
价 格:¥电议型 号:T11177产 地:中国大陆