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T70800Elenbecestat free base;化合物 Elenbecestat free baseElenbecestat free base
Elenbecestat,also known as E2609 is a BACE1 inhibitor. By inhibiting BACE, a key enzyme in the production of Aβ peptides, E2609 decreases the formation of these peptides which can aggregate into toxic oligomers and protofibrils and eventually form amyloid plaques in the brain. Elenbecestat has been shown to reduce Aβ levels in cerebrospinal fluid, was investigated in two global phase 3 studies in early AD.
价 格:¥电议型 号:T70800产 地:中国大陆
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T70793Parogrelil Free Base;帕格雷利NM-702 Free Base;NM-702 Free Base
Parogrelil Free Base (NM-702 Free Base) is a selective phosphodiesterase 3 inhibitor with bronchodilatory and anti-inflammatory effects, inhibits leukotriene (LT)D(4) and histamine-induced constriction of isolated guinea pig tracheal strips, and can be used in the study of bronchial asthma.
价 格:¥电议型 号:T70793产 地:中国大陆
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T70776AS-1669058 free base;化合物 AS-1669058 free baseAS-1669058 free base
AS-1669058 free base is a G-protein-coupled receptor 119 (GPR119) agonist used to as new drug to treat type 2 diabetes.
价 格:¥电议型 号:T70776产 地:中国大陆
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T70770Cyclazosin Free Base;化合物 Cyclazosin Free BaseCyclazosin Free Base
Cyclazosin Free Base is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of furoic acid with the secondary amino group of 6,7-dimethoxy-2-[(4aR,8aS)-octahydroquinoxalin-1-yl]quinazolin-4-amine. It has a role as an adenosine A2A receptor antagonist. It is a member of quinazolines, a member of furans, an aromatic ether, a quinoxaline derivative, an aromatic amide and a monocarboxylic acid amide.
价 格:¥电议型 号:T70770产 地:中国大陆
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T70752Neomycin (free base);化合物 Neomycin (free base)Neomycin (free base)
Neomycin (free base) is an antibiotic complex produced by Streptomyces fradiae. It is composed of neomycins A, B, and C. It acts by inhibiting translation during protein synthesis.
价 格:¥电议型 号:T70752产 地:中国大陆
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T70751PF-719 free base;化合物 PF-719 free basePF-719 free base
PF-719 is a potent, selective Pyk2 inhibitor with IC50 of 17 nM.
价 格:¥电议型 号:T70751产 地:中国大陆
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T70555Tecalcet Free Base;化合物 Tecalcet Free BaseTecalcet Free Base
Tecalcet Free Base is an oral calcium receptor agonist
价 格:¥电议型 号:T70555产 地:中国大陆
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T70513NB-506 Free Base;化合物 NB-506 Free BaseNB-506 Free Base
NB-506 Free Base is an indolocarbazole antitumor agent; a DNA topoisomerase I inhibitor.
价 格:¥电议型 号:T70513产 地:中国大陆
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T70487Tofenacin (free base);化合物 Tofenacin (free base)Tofenacin (free base)
Tofenacin (free base) is an antidepressant drug with a tricyclic-like structure. It acts as a serotonin-norepinephrine reuptake inhibitor, and based on its close relation to orphenadrine, may also possess anticholinergic and antihistamine properties. Tofenacin is also the major active metabolite of orphenadrine and likely plays a role in its beneficial effects against depressive symptoms seen in Parkinson´s disease patients.
价 格:¥电议型 号:T70487产 地:中国大陆
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T70482DMP-728 free base;化合物 DMP-728 free baseDMP-728 free base
DMP-728 free base is a highly potent and selective GPIIbDIIa antagonist
价 格:¥电议型 号:T70482产 地:中国大陆
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T70473Parapenzolate Free Base;化合物 Parapenzolate Free BaseParapenzolate Free Base
Parapenzolate Free Base is a safe and effective anticholinergic drug possessing antisecretory and antimotility properties and prolonged duration of action. Clinical investigation has shown that after an oral dose of the drug there was inhibition of both basal and histamine-stimulated acid outputs.
价 格:¥电议型 号:T70473产 地:中国大陆
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T70456Nolpitantium Free Base;化合物 Nolpitantium Free BaseNolpitantium Free Base
Nolpitantium Free Base is a highly selective nonpeptide antagonist of neurokinin-1 (NK1) receptor. Nolpitantium potently, selectively and competitively inhibited substance P binding to NK1 receptors from various animal species, including humans. In vitro, it was a potent antagonist in functional assays for NK1 receptors such as [Sar9, Met(O2)11]substance P-induced endothelium-dependent relaxation of rabbit pulmonary artery and contraction of guinea-pig ileum. Up to 1 mkM, Nolpitantium had no eff
价 格:¥电议型 号:T70456产 地:中国大陆
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T70412PNU-145156E free base;化合物 PNU-145156E free basePNU-145156E free base
PNU-145156E free base is an angiogenesis inhibitor.
价 格:¥电议型 号:T70412产 地:中国大陆
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T70407cemadotin free base;西马多丁LU103793 free base;LU103793 free base
Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocks mitosis and inhibits microtubules (tubulin) with a Ki of 1 μM. Cemadotin is used in research against cancer.
价 格:¥电议型 号:T70407产 地:中国大陆
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T70406Droxinavir Free Base;化合物 Droxinavir Free BaseDroxinavir Free Base
Droxinavir Free Base is an experimental protease inhibitor researched by Pharmacia as a treatment for HIV infection.
价 格:¥电议型 号:T70406产 地:中国大陆
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T70381GSK2793660 free base;化合物 GSK2793660 free baseGSK2793660 free base
GSK-2793660 is a cathepsin C inhibitor that may be useful in the treatment of cystic fibrosis, noncystic fibrosis bronchiectasis, ANCA-associated vasculitis and bronchiectasis.
价 格:¥电议型 号:T70381产 地:中国大陆
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T70311Demecarium Free Base;化合物 Demecarium Free BaseDemecarium Free Base
Demecarium Free Base is a quaternary ammonium compound that serves as a long-acting cholinesterase inhibitor with parasympathomimetic activity. When used topically, demecarium inactivates both pseudocholinesterase and acetylcholinesterase, thereby preventing acetylcholine breakdown and increasing acetylcholine activity.
价 格:¥电议型 号:T70311产 地:中国大陆
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T70294KAA-276 free base;化合物 KAA-276 free baseKAA-276 free base
KAA-276 free base is a novel potent and long-lasting histamine HI-receptor antagonist with less-topical irritation, and can be topically administered by inhalation for the treatment of bronchial asthma.
价 格:¥电议型 号:T70294产 地:中国大陆
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T70278FR-168888 free base;化合物 FR-168888 free baseFR-168888 free base
FR-168888 free base is a new Na+/H+ exchange inhibitor. FR-168888 has a strong inhibitory effect on Na+/H+ exchange and has been shown to protect the heart from arrhythmia and myocardial cell death in ischemic and reperfused situations.
价 格:¥电议型 号:T70278产 地:中国大陆
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T70259AMD-3329 free base;化合物 AMD-3329 free baseAMD-3329 free base
AMD-3329 free base is a biochemical in the class of potent and selective anti-HIV-1 and HIV-2 agents that inhibit virus replication by binding to the chemokine receptor CXCR4, the co-receptor for entry of X4 viruses.
价 格:¥电议型 号:T70259产 地:中国大陆