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T74180[18F]-Labeled L-dopa precursor;化合物 [18F]-Labeled L-dopa precursor[18F]-Labeled L-dopa precursor
[18F]-Labeled L-dopa precursor is a precursor for synthesis of 18F-labeled L-dopa[1].
价 格:¥电议型 号:T74180产 地:中国大陆
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T74147Larsucosterol (trimethylamine);化合物 Larsucosterol (trimethylamine)Larsucosterol (trimethylamine)
Larsucosterol (DUR-928) trimethylamine, a metabolite of cholesterol, functions as a powerful liver X receptor (LXR) antagonist, effectively reducing lipogenesis and inhibiting cholesterol biosynthesis. It achieves this by decreasing mRNA levels and suppressing the activation of SREBP-1 [1] [2] [3].
价 格:¥电议型 号:T74147产 地:中国大陆
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T74145Deutarserine;化合物 DeutarserineDeutarserine
Deutarserine, a deuterium-modified analog of the endogenous compound D-serine (CTP 692), is utilized in schizophrenia research in adults [1].
价 格:¥电议型 号:T74145产 地:中国大陆
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T74143AZD4694 Precursor;化合物 AZD4694 PrecursorAZD4694 Precursor
AZD4694 Precursor (AZ13040214) serves as the foundational compound for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging ligand targeting amyloid-β plaques [1].
价 格:¥电议型 号:T74143产 地:中国大陆
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T7414ARS-853;化合物ARS-853ARS-853
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
价 格:¥电议型 号:T7414产 地:中国大陆
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T74014Seco Rapamycin ethyl ester;化合物 Seco Rapamycin ethyl esterSeco Rapamycin ethyl ester
Seco Rapamycin ethyl ester, an open-ring metabolite of the Rapamycin derivative, reportedly does not impact mTOR function [1].
价 格:¥电议型 号:T74014产 地:中国大陆
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T73993Fazirsiran;化合物 FazirsiranFazirsiran
Fazirsiran (ARO-AAT), a second-generation RNAi agent, comprises a cholesterol-conjugated RNAi trigger (chol-RNAi) that selectively degrades AAT mRNA via RNAi, and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) as the excipient EX1 to enhance endosomal escape of chol-RNAi in hepatocytes [1].
价 格:¥电议型 号:T73993产 地:中国大陆
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T73800Retreversine;化合物 RetreversineRetreversine
Retreversine serves as an inactive control counterpart to Reversine, a pioneering class of ATP-competitive Aurora kinase inhibitor.
价 格:¥电议型 号:T73800产 地:中国大陆
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T73749Fomivirsen;化合物 FomivirsenFomivirsen
Fomivirsen (ISIS-2922 free base), a 21-mer phosphorothioate antisense oligonucleotide, serves as an antiviral agent, particularly in CMV research, including AIDS studies. It functions by binding to and degrading the mRNAs that encode for the CMV immediate-early 2 protein, effectively inhibiting viral proliferation [1] [2].
价 格:¥电议型 号:T73749产 地:中国大陆
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T73549RSH-7;化合物RSH-7RSH-7
RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducing apoptosis and inhibiting BTK and FLT3 signaling.
价 格:¥电议型 号:T73549产 地:中国大陆
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T7353RSV604;化合物RSV604(S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)u
RSV604 ((S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea) is an inhibitor of respiratory syncytial virus (RSV) that binds to RSV nucleoprotein (Kd = 1.31 μM)
价 格:¥电议型 号:T7353产 地:中国大陆
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T73453MRS4719;化合物 MRS4719MRS4719
MRS4719, a potent P2X4 receptor antagonist, exhibits a half-maximal inhibitory concentration (IC50) of 0.503 μM for the human P2X4 receptor. Demonstrating both neuroprotective and neuro-rehabilitative effects, it can decrease infarct volume and brain atrophy in an ischemic stroke model. Additionally, MRS4719 mitigates ATP-induced calcium influx in primary human monocyte-derived macrophages, making it a valuable tool for researching ischemic stroke.
价 格:¥电议型 号:T73453产 地:中国大陆
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T73452MRS4596;化合物 MRS4596MRS4596
MRS4596, a potent and selective antagonist of the P2X4 receptor, exhibits an IC50 of 1.38 μM for the human P2X4 receptor. This compound demonstrates both neuroprotective and neuro-rehabilitative effects in ischemic stroke models, making it valuable for research purposes in the context of ischemic stroke.
价 格:¥电议型 号:T73452产 地:中国大陆
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T73396ARS-2102;化合物 ARS-2102ARS-2102
ARS-2102 is a potent covalent KRAS G12C inhibitor for use in cancer research [1] .
价 格:¥电议型 号:T73396产 地:中国大陆
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T73370RSV-IN-7;化合物 RSV-IN-7RSV-IN-7
RSV-IN-7 (example 253) is a RSV inhibitor ( EC 50 : < 0.4 μΜ) [1] .
价 格:¥电议型 号:T73370产 地:中国大陆
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T7331Ursocholic acid;熊果胆酸Ursocholic acid
Ursocholic acid, a bile acid found predominantly in bile of mammals.
价 格:¥电议型 号:T7331产 地:中国大陆
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T73268hRSV-IN-1;化合物 hRSV-IN-1hRSV-IN-1
hRSV-IN-1 is an inhibitor of respiratory syncytial virus (hRSV) [1] [2] .
价 格:¥电议型 号:T73268产 地:中国大陆
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T73123ThrRS-IN-3;化合物 ThrRS-IN-3ThrRS-IN-3
ThrRS-IN-3, a threonyl-tRNA synthetase (ThrRS) inhibitor, exhibits high potency, demonstrated by an IC50 of 19 nM and a Kd of 34 nM against Salmonella enterica ThrRS. It also possesses antibacterial activities.
价 格:¥电议型 号:T73123产 地:中国大陆
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T72921Reversin 121;化合物 Reversin 121Reversin 121
Reversin 121, a P-glycoprotein inhibitor, enhances MDR1´s ATPase activity and counteracts P-glycoprotein-mediated multidrug resistance, making it useful in cancer research.
价 格:¥电议型 号:T72921产 地:中国大陆
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T72904Norswertianin;化合物 NorswertianinNorswertianin
Norswertianin, a xanthone-based compound, acts as a potent anti-glioma agent. It promotes differentiation of GBM cells via oxidative stress and autophagy dependent on Akt/mTOR signaling.
价 格:¥电议型 号:T72904产 地:中国大陆