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T6263Safflower-yellow;红花黄色素Safflower-yellow
Safflower yellow is extracted from the flowers of the plant safflower (Carthamus tinctorius) and as the traditional Chinese medicine it has been extensively used for the treatment of cardio cerebrovascular diseases.
价 格:¥电议型 号:T6263产 地:中国大陆
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T62629HPK1-IN-13;化合物 HPK1-IN-13HPK1-IN-13
HPK1-IN-13 is a potent inhibitor of HPK1. HPK1-IN-12 has potential for the study of HPK1-related diseases.
价 格:¥电议型 号:T62629产 地:中国大陆
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T62628HPK1-IN-12;化合物 HPK1-IN-12HPK1-IN-12
HPK1-IN-12 is a potent inhibitor of HPK1. HPK1-IN-12 has potential for the study of HPK1-related diseases.
价 格:¥电议型 号:T62628产 地:中国大陆
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T62627Antibacterial agent 69;化合物 Antibacterial agent 69Antibacterial agent 69
Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 μM).
价 格:¥电议型 号:T62627产 地:中国大陆
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T62626HBV-IN-12;化合物 HBV-IN-12HBV-IN-12
HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg) (0.001 μM < EC50 ≤ 0.05 μM). HBV-IN-12 is anti-HBV DNA (0.001 μM < EC50 ≤ 0.02 μM).
价 格:¥电议型 号:T62626产 地:中国大陆
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T62624LpxA-IN-1;化合物 LpxA-IN-1LpxA-IN-1
LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) of 8 μg/mL.
价 格:¥电议型 号:T62624产 地:中国大陆
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T62623G247;化合物 G247G247
G247 is a specific inhibitor of MsbA, a wedge of transmembrane structural domains (TMDs) that symmetrically enhances the separation of nucleotide-binding domains (NBDs) and prevents conformational transitions of MsbA. G247 increases the distance between NBDs, thereby inhibiting ATPase activity.
价 格:¥电议型 号:T62623产 地:中国大陆
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T62622MRL-871;化合物 MRL-871MRL-871
MRL-871 (compound 3) is a potent isotretinoin receptor-related orphan receptor γt (RORγt) inverse agonist (IC50: 264 nM).MRL-871 has a specific isoxazole chemotype and is effective in reducing IL-17a mRNA production in EL4 cells.
价 格:¥电议型 号:T62622产 地:中国大陆
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T62621pan-HER-IN-2;化合物 pan-HER-IN-2pan-HER-IN-2
pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50: 8.2 nM), and L858R (IC50: 75.1 nM). pan-HER-IN-2 induces apoptosis and has anti-tumour effects.
价 格:¥电议型 号:T62621产 地:中国大陆
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T62620ZY-444;化合物 ZY-444ZY-444
ZY-444 has potential anticancer activity, inhibits PCa cell proliferation and metastasis, and inhibits the growth of subcutaneous tumors.
价 格:¥电议型 号:T62620产 地:中国大陆
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T6262Evacetrapib;化合物EvacetrapibLY2484595;LY2484595
Evacetrapib (LY2484595) (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
价 格:¥电议型 号:T6262产 地:中国大陆
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T62618SPH3127;化合物 SPH3127SPH3127
SPH3127 (DRI 18) is a potent, orally active, novel direct renin inhibitor with IC50 values of 0.4 nM and 0.45 nM for recombinant human-renin and human plasma renin activity, respectively. SPH3127 has an anti-hypertensive effect and can be used to study hypertension.
价 格:¥电议型 号:T62618产 地:中国大陆
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T62617QW24;化合物 QW24QW24
QW24 down-regulates BMI-1, exhibits potent antitumour effects and is used as an effective therapeutic agent in the treatment of clinical colorectal cancer.
价 格:¥电议型 号:T62617产 地:中国大陆
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T62615ALK5-IN-30;化合物 ALK5-IN-30ALK5-IN-30
ALK5-IN-30 (EX-07) is a potent inhibitor of ALK with inhibitory effects on ALK5 (IC50< 10 nM) and TGFβ-R1 (IC50< 10 nM).
价 格:¥电议型 号:T62615产 地:中国大陆
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T62614ALK5-IN-29;化合物 ALK5-IN-29ALK5-IN-29
ALK5-IN-29 is a selective inhibitor of activin receptor-like kinase (ALK).ALK5-IN-29 inhibits activin receptor-like kinase activity (IC50 ≤ 10 nM).AALK5-IN-29 inhibits tumour growth and can be used in the study of proliferative diseases such as cancer.
价 格:¥电议型 号:T62614产 地:中国大陆
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T62613ALK5-IN-26;化合物 ALK5-IN-26ALK5-IN-26
ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 (IC50 ≤ 1 nM).
价 格:¥电议型 号:T62613产 地:中国大陆
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T62612CD33 splicing modulator 1;化合物 CD33 splicing modulator 1CD33 splicing modulator 1
CD33 splicing modulator 1 (Compound 1) is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid cell surface receptor known to regulate microglial cell activity. CD33 splicing modulator 1 has potential for the study of neurodegenerative diseases, including Alzheimer´s disease.
价 格:¥电议型 号:T62612产 地:中国大陆
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T62611Adenosine receptor antagonist 2;化合物 Adenosine receptor antagonist 2Adenosine receptor antagonist 2
Adenosine receptor antagonist 2 is an orally active A2a (IC50: 1 nM), A2b (IC50: 3 nM) adenosine receptor antagonist that exhibits antitumour effects.
价 格:¥电议型 号:T62611产 地:中国大陆
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T62610LY3154885;化合物 LY3154885LY3154885
LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).
价 格:¥电议型 号:T62610产 地:中国大陆
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T6261CP-466722;化合物CP466722CP 466722|||CP466722;CP 466722|||CP466722
CP-466722, an effective and reversible ATM inhibitor, does not inhibit ATR and PI3K or PIKK family members in cells.
价 格:¥电议型 号:T6261产 地:中国大陆