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T11583HWL-088;化合物 T11583HWL-088
HWL-088 is a potent free fatty acid receptor 1 (FFA1/GPR40) agonist. HWL-088 significantly improves glucose tolerance in normal and diabetic models.
价 格:¥电议型 号:T11583产 地:中国大陆
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T11582HSV-TK substrate;化合物 T11582HSV-TK substrate
HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells.
价 格:¥电议型 号:T11582产 地:中国大陆
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T11581HSR6071;化合物HSR6071HSR6071
HSR6071 is a novel orally active and potent anti-allergic agent with inhibitory effects on passive cutaneous anaphylaxis. HSR6071 showed anti-asthmatic activity in a rat model of experimental asthma.
价 格:¥电议型 号:T11581产 地:中国大陆
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T11580LHeme Oxygenase-1-IN-1 hydrochloride;化合物 T11580LHO-1-IN-1 hydrochloride;HO-1-IN-1 hydrochloride
HO-1-IN-1 hydrochloride is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).
价 格:¥电议型 号:T11580L产 地:中国大陆
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T11580Heme Oxygenase-1-IN-1;化合物Heme Oxygenase-1-IN-1HO-1-IN-1;HO-1-IN-1
Heme Oxygenase-1-IN-1 (HO-1-IN-1) is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).
价 格:¥电议型 号:T11580产 地:中国大陆
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T1158Phenoxybenzamine hydrochloride;盐酸酚苄明NCI-c01661|||NSC 37448|||Phenoxybenzamine HCl;苯氧苯札明|||NCI-c01661
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors whi
价 格:¥电议型 号:T1158产 地:中国大陆
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T11579HSL-IN-3;化合物HSL-IN-3HSL inhibitor 3|||Ethyl 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate;HSL inh
HSL-IN-3 (HSL inhibitor 3) is a boronic acid derivative that is an inhibitor of hormone-sensitive lipase(HSL).
价 格:¥电议型 号:T11579产 地:中国大陆
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T11578LEncequidar mesylate;化合物Encequidar mesylateHM30181 mesylate|||HM30181A mesylate;HM30181 mesylate|||HM
Encequidar mesylate (HM30181A mesylate) is a competitive P-glycoprotein inhibitor.
价 格:¥电议型 号:T11578L产 地:中国大陆
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T11577BAY 59-9435;化合物 T11577HSL-IN-2;HSL-IN-2
HSL-IN-2 is a selective inhibitor of Hormone Sensitive Lipase (HSL; IC50: 0.023 μM).
价 格:¥电议型 号:T11577产 地:中国大陆
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T11576HSL-IN-1;化合物 T11576HSL-IN-1
HSL-IN-1 is an orally active hormone-sensitive lipase (HSL) inhibitor (IC50: 2 nM) with a significantly reduced reactive metabolite liability.
价 格:¥电议型 号:T11576产 地:中国大陆
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T11575HS80;化合物 T11575HS80
HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids (IC50: 7.13 μM).
价 格:¥电议型 号:T11575产 地:中国大陆
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T11574HS79;化合物 T11574HS79
HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids (IC50: 1.57 μM).
价 格:¥电议型 号:T11574产 地:中国大陆
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T11573HPN-01;化合物 T11573HPN-01
HPN-01 is a selective IKK inhibitor (pIC50s: 6.4, 7.0, and <4.8 for IKK-α, IKK-β, and IKK-ε). HPN-01 displays greater 50-fold selectivity over a panel of more than 50 other kinases, including ALK5, CDK-2, ErbB2, EGFR, GSK3β, Src, PLK1, and VEGFR-2.
价 格:¥电议型 号:T11573产 地:中国大陆
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T11572HMG499;化合物 T11572HMG499
HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC 50 of 0.41 μM. HMG499 can eliminate statins-induced accumulation of HMGCR, lower serum cholesterol levels and decrease atherosclerosis [1].
价 格:¥电议型 号:T11572产 地:中国大陆
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T11571HLY78化合物HLY784-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine
HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.
价 格:¥电议型 号:T11571产 地:中国大陆
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T11570HL271;化合物 T11570HL271
HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.
价 格:¥电议型 号:T11570产 地:中国大陆
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T1157Moxidectin;莫昔克丁milbemycin B|||CL301423;milbemycin B|||CL301423|||莫昔克丁|||莫西菌素
Moxidectin (CL301423) is an anthelmintic drug which kills parasitic worms, and is used for the prevention and control of heartworm and intestinal worms. It can be found in treatments prescribed for animals such as dogs, cats, horses, cattle and sheep. Application methods for moxidectin vary by treatment, and include oral, topical, and injectable solutions. Cydectin Pour On is a trade name for a formulation for use on cattle and red deer.
价 格:¥电议型 号:T1157产 地:中国大陆
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T11569HKI-357;化合物HKI-357HKI-357
HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 (IC50s: 34 nM and 33 nM). HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.
价 格:¥电议型 号:T11569产 地:中国大陆
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T11568HIV-1 integrase inhibitor 4;化合物 T11568HIV-1 integrase inhibitor 4
HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM).
价 格:¥电议型 号:T11568产 地:中国大陆
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T11567HIV-1 integrase inhibitor 3;化合物 T11567HIV-1 integrase inhibitor 3
HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM).
价 格:¥电议型 号:T11567产 地:中国大陆