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T10835L1Cletoquine hydrochloride;盐酸氯托喹Cletoquine hydrochloride( 4298-15-1 Free base);Cletoquine hydrochlorid
Cletoquine hydrochloride is a major active metabolite of Hydroxychloroquine. Cletoquine hydrochloride is a Chloroquine derivative and exhibits the ability to against the chikungunya virus (CHIKV). Cletoquine hydrochloride exhibits antimalarial effects.
价 格:¥电议型 号:T10835L1产 地:中国大陆
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T10815Cinnamoylglycine;N-肉桂酰甘氨酸Cinnamoylglycine
Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in humans. It is used as a potential urinary biomarker.
价 格:¥电议型 号:T10815产 地:中国大陆
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T10801CHMFL-ABL/KIT-155;化合物 T10801CHMFL-ABL-KIT-155;CHMFL-ABL-KIT-155
CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM). It arrests cell cycle progression and induces apoptosis.
价 格:¥电议型 号:T10801产 地:中国大陆
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T10788LChitinase-IN-2 hydrochloride;化合物 T10788LChitinase-IN-2 hydrochloride (1579991-63-1 free base);Chitin
Chitinase-IN-2 hydrochloride functions as an inhibitor of both insect chitinase and N-acetyl hexosaminidase, and also serves as a pesticide. At concentrations of 50 ?M and 20 ?M, it demonstrates inhibitory effectiveness of 98% and 92% against chitinase and N-acetyl-hexosaminidase, respectively.
价 格:¥电议型 号:T10788L产 地:中国大陆
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T10783CGS 15435;化合物CGS 15435CGS 15435
CGS 15435 is a potent thromboxen (TxA2) synthetase inhibitor (IC50: 1 nM). CGS 15435 acts on PGI2 synthase, cyclooxygenase and liposynthase with much less selectivity than on thromboxin synthase.
价 格:¥电议型 号:T10783产 地:中国大陆
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T10780CGP-53153;化合物 T10780CGP-53153
CGP-53153 is a steroidal inhibitor of 5 alpha-reductase (IC50s: 36 and 262 nM in rat and human prostatic tissue).
价 格:¥电议型 号:T10780产 地:中国大陆
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T10718LCCT241533 hydrochloride;化合物 T10718LCCT241533 hydrochloride
CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
价 格:¥电议型 号:T10718L产 地:中国大陆
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T10718CCT241533;化合物 T10718CCT241533
CCT241533 is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
价 格:¥电议型 号:T10718产 地:中国大陆
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T10715CCR6 inhibitor 1;化合物CCR6 inhibitor 1CCR6 inhibitor 1
CCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively). CCR6 is associated with both autoimmune and non-autoimmune diseases, so CCR6 inhibitor 1 is useful for in vitro and in vivo pathophysiology studies as a small molecule inhibitor of CCR6.
价 格:¥电议型 号:T10715产 地:中国大陆
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T10695CB1151;化合物 T10695CB1151
CB1151 is a 20-epi analogue of 1,25 dihydroxyvitamin D3 with anti-tumor effects. It inhibits MCF-7 cell growth (IC50: 0.82 nM).
价 格:¥电议型 号:T10695产 地:中国大陆
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T10692LNumidargistat;化合物 T10692LINCB01158|||CB-1158;INCB01158|||CB-1158
CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2).
价 格:¥电议型 号:T10692L产 地:中国大陆
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T10692CB-1158 dihydrochloride (2095732-06-0 free base);化合物 T10692INCB01158 dihydrochloride|||CB-1158 dihyd
CB-1158 dihydrochloride is an effective and orally active inhibitor of arginase (IC50s: 86 nM and 296 nM for recombinant human arginase 1 and 2).
价 格:¥电议型 号:T10692产 地:中国大陆
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T10615BRL44385;化合物 T10615BRL44385
BRL44385 is an effective and selective inhibitor of the replication of HSV-1 and HSV2, Epstein-Barr virus (EBV), and varicella-zoster virus (VZV).
价 格:¥电议型 号:T10615产 地:中国大陆
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T10614BRL-42715;化合物 T10614BRL-42715
BRL-42715 is an effective inhibitor of bacterial beta-lactamases.
价 格:¥电议型 号:T10614产 地:中国大陆
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T10602BRD 4354 ditrifluoroacetate;化合物 T10602BRD 4354 ditrifluoroacetate (315698-07-8 free base);BRD 4354 d
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).
价 格:¥电议型 号:T10602产 地:中国大陆
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T10589LBPN-15606;化合物 T10589LBPN-15606
BPN-15606, an orally active γ-secretase modulator (GSM), significantly reduces Aβ42 and Aβ40 production in SHSY5Y neuroblastoma cells, demonstrating IC50 values of 7 nM and 17 nM, respectively. This compound exhibits favorable pharmacokinetic/pharmacodynamic (PK/PD) properties, such as bioavailability, half-life, and clearance. Importantly, BPN-15606 markedly decreases Aβ42 and Aβ40 levels in the central nervous system of both rats and mice[1].
价 格:¥电议型 号:T10589L产 地:中国大陆
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T10589BPN-15606 besylate (1914989-49-3 free base);化合物 T10589BPN-15606 besylate;BPN-15606 besylate
BPN-15606 besylate is a highly potent, orally active γ-secretase modulator, attenuates the production of Aβ40 and Aβ42 by SHSY5Y neuroblastoma cells (IC50s: 7 nM and 17nM).
价 格:¥电议型 号:T10589产 地:中国大陆
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T10571BMS-901715;化合物 T10571BMS-901715
BMS-901715 is an effective and selective inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50: 3.3 nM).
价 格:¥电议型 号:T10571产 地:中国大陆
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T10547BioE-1115;化合物BioE-1115BioE-1115
BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).
价 格:¥电议型 号:T10547产 地:中国大陆
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T10515Anti-Heart Failure Agent 1;化合物 T10515Anti-Heart Failure Agent 1
Anti-Heart Failure Agent 1 is an orally available compound suitable for the treatment of heart failure without inducing vomiting, nausea, and restlessness.
价 格:¥电议型 号:T10515产 地:中国大陆