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产品数:86101
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T6730WAY-600inhibit,Inhibitor,mTOR,WAY 600,WAY-600,Mammalian target of Rapamycin
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
价 格:¥电议型 号:T6730产 地:中国大陆
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T9423Alkyne tyramideAlkyne tyramide,membrane,mitochondria,topology,Inhibitor,inhibit,APEX2,substrate,yeas
Alkyne tyramide is a clickable ascorbate peroxidase 2 (APEX2) probe which enable biotin-independent detection of labeled proteins.
价 格:¥电议型 号:T9423产 地:中国大陆
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TQ018514-Deoxy-11,12-didehydroandrographolideinhibit,Nuclear factor-κB,Inhibitor,14 Deoxy 11,12 didehydroa
14-Deoxy-11,12-didehydroandrographolide has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.
价 格:¥电议型 号:TQ0185产 地:中国大陆
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T7926CarmoisineInhibitor,Artificial,Acid Red-14,E122,colorant,E-122,Carmoisine,inhibit,MAPK8,proinflammat
Azo Rubine is a food dye Azorubine and is used for the purposes where food is heat-treated after fermentation.
价 格:¥电议型 号:T7926产 地:中国大陆
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T9533BC-LI-0186Aminoacyl-tRNA Synthetase,RagD,rapamycin-resistant,BCLI0186,tRNA Synthetase, aaRS,H460,KRA
BC-LI-0186 is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protein D (RagD) with IC50 of 46.11 nM. BC-LI-0186 competitively binds the RagD interaction site of LRS with Kd of 42.1 nM and has no effect on LRS-vps34, LRS-eprs, RagB-RagD association, mTORC1 complex formation. BC-LI-0186 potently inhibits the activity of tumor-associated MTOR mutants and the growth of rapamycin-resistant cancer cells. BC-LI-0186 can be used for lung c
价 格:¥电议型 号:T9533产 地:中国大陆
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T6682STF-118804Inhibitor,STF-118804,inhibit,Pre-B cell colony enhancing factor,Apoptosis,Nicotinamide pho
STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.
价 格:¥电议型 号:T6682产 地:中国大陆
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T9575MRTX9768SDMA,toxicity,glioblastoma,orally,MRTX9768,low,Inhibitor,hematological,MRTX-9768,MTAP,CDKN2A
MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.
价 格:¥电议型 号:T9575产 地:中国大陆
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T9105NF-κB-IN-1pathway,4-arylidene,Inhibitor,inhibit,IKK,crucumin,cancer,A549,NFκBIN1,I kappa B kinase,si
NF-κB-IN-1 is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 directly inhibits IKK to block NF-κB activation. NF-κB-IN-1 effectively inhibits the viability of lung cancer cells and attenuates the clonogenic activity of A549 cells.
价 格:¥电议型 号:T9105产 地:中国大陆
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TQ0306MLN120BMLN120B,ML120B,Inhibitor,I kappa B kinase,inhibit,IKK,IκB kinase,MLN-120B
MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).
价 格:¥电议型 号:TQ0306产 地:中国大陆
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T39823LApelin-12 acetate
Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 MAPK signaling pathway of the apoptosis-related MAPKs family, thus offering protection to neurons.
价 格:¥电议型 号:T39823L产 地:中国大陆
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T7337Kinetin ribosideApoptosis,inhibit,Kinetin riboside,Inhibitor
Kinetin riboside can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)
价 格:¥电议型 号:T7337产 地:中国大陆
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T6673SKI IISKI II,Sphingosine kinase,Apoptosis,SphK,Wnt,Inhibitor,inhibit
SKI II is a highly selective and non-ATP-competitive S1P receptor inhibitor (IC50: 0.5 μM) while exhibiting no inhibitory action on other kinases including PKCα, PI3K, and ERK2.
价 格:¥电议型 号:T6673产 地:中国大陆
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T9110Ceapin-A7UPR,Inhibitor,CeapinA7,stress,unfolded protein response,reticulum,Golgi,endoplasmic,Ceapin-
Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings.
价 格:¥电议型 号:T9110产 地:中国大陆
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T7350Nelotanserin5-HT Receptor,Inhibitor,APD 125,inhibit,APD-125,Nelotanserin,Serotonin Receptor,5-hydrox
Nelotanserin is a potent 5-HT2A inverse agonist(IC50 : 1.7 nM), a moderately potent 5-HT2C partial inverse agonist t(IC50 :79 nM )and a weak 5-HT2B inverse agonistt(IC50 : 791 nM).
价 格:¥电议型 号:T7350产 地:中国大陆
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T3242BreviscapinBreviscapin
Breviscapine is the total flavonoid components (the content of scutellarin > or =85%) extracted from the dried whole plant of Erigeron breviscapus.
价 格:¥电议型 号:T3242产 地:中国大陆
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T8128Mosapride5-hydroxytryptamine Receptor,inhibit,Inhibitor,TAK 370,Mosapride,TAK370,5-HT Receptor,Serot
Mosapride is a selective 5HT4 agonist
价 格:¥电议型 号:T8128产 地:中国大陆
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T9497Niraparib tosylate monohyrateNiraparib tosylate,Apoptosis,cancer,MK-4827 tosylate,inhibit,breast,PAR
Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base-excision repair (BER) pathway.
价 格:¥电议型 号:T9497产 地:中国大陆
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T7661SD-169HSPs,p38α,kinases,SD-169,protein,inhibit,Inhibitor,p38 MAPK,MAPK,SD169,heat,diabete,mitogen-ac
SD 169 is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.
价 格:¥电议型 号:T7661产 地:中国大陆
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T6400AZD3514selective,anti proliferation,LAPC4,Inhibitor,AZD3514,AZD-3514,oral,AZD 3514,rat,AR protein,pr
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
价 格:¥电议型 号:T6400产 地:中国大陆
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T8926Salcaprozate sodiuminhibit,delivery,Inhibitor,non-covalent,absorption,lipophilicity,Salcaprozate sod
Salcaprozate sodium is an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. It could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation.
价 格:¥电议型 号:T8926产 地:中国大陆