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T62894AZ-PFKFB3-67 quarterhydrate;化合物 AZ-PFKFB3-67 quarterhydrateAZ-PFKFB3-67 quarterhydrate
AZ-PFKFB3-67 quarterhydrate is a selective and potent inhibitor of the metabolic kinase PFKFB3 kinase, acting on PFKFB3 (IC50: 11 nM), PFKFB2 (IC50: 159 nM) and PFKFB1 (IC50: 1130 nM).
价 格:¥电议型 号:T62894产 地:中国大陆
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T62846Freselestat quarterhydrate;化合物 Freselestat quarterhydrateFreselestat quarterhydrate
Freselestat quarterhydrate (ONO-6818 quarterhydrate) is a potent, orally active inhibitor of neutrophil elastase (Ki: 12.2 nM). quarterhydrate is more than 100-fold less active than other proteases such as trypsin, proteinase 3, pancreatic elastase, thrombin, fibrin, collagenase, histone G and murine macrophage elastase, and exhibits potent anti-inflammatory effects.
价 格:¥电议型 号:T62846产 地:中国大陆
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T6279Givinostat hydrochloride monohydrate;吉维司他ITF2357|||ITF-2357 hydrochloride monohydrate|||Givinostat||
Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.
价 格:¥电议型 号:T6279产 地:中国大陆
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T62691Syk Inhibitor II dihydrochloride dihydrate;化合物 Syk Inhibitor II dihydrochloride dihydrateSyk Inhibit
Syk Inhibitor II dihydrochloride dihydrate is a highly selective, potent, ATP-competitive Syk inhibitor (IC50: 41 nM). Syk Inhibitor II dihydrochloride dihydrate exhibits anti-allergic effects.
价 格:¥电议型 号:T62691产 地:中国大陆
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T6265Bosentan (hydrate);波生坦水合物Bosentan Hydrate|||Benzenesulfonamide|||Actelion|||Ro 47-0203;波生坦水合物|||Bose
Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
价 格:¥电议型 号:T6265产 地:中国大陆
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T62604Flunisolide hemihydrate;化合物 Flunisolide hemihydrateFlunisolide hemihydrate
Flunisolide hemihydrate is a corticosteroid, an orally active Glucocorticoid receptor activator with anti-inflammatory effects. flunisolide hemihydrate induces apoptosis in eosinophils and can be used in asthma or rhinitis, inflammatory diseases. Can be used in studies related to asthma or rhinitis, inflammation.
价 格:¥电议型 号:T62604产 地:中国大陆
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T62520Imidocarb dihydrochloride monohydrate;化合物 Imidocarb dihydrochloride monohydrateImidocarb dihydrochlo
Imidocarb dihydrochloride monohydrate is an effective antiprotozoal agent against the parasite B. bovis (IC50: 87 μg/ml).
价 格:¥电议型 号:T62520产 地:中国大陆
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T62382Tiagabine hydrochloride hydrate;化合物 Tiagabine hydrochloride hydrateTiagabine hydrochloride hydrate
Tiagabine hydrochloride hydrate is a potent and selective inhibitor of GABA uptake; it inhibits [3H] GABA uptake in synaptosomes, neurons and glia, with IC50 values of 67, 446 and 182 nM respectively. hydrate can be used as an anticonvulsant.
价 格:¥电议型 号:T62382产 地:中国大陆
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T62265(+)-Sparteine sulfate pentahydrate;化合物 (+)-Sparteine sulfate pentahydrate(+)-Sparteine sulfate penta
(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.
价 格:¥电议型 号:T62265产 地:中国大陆
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T6226Pemetrexed disodium hemipenta hydrate;培美曲塞二钠水合物Pemetrexed Disodium Hydrate|||LY-231514 Disodium Hydr
Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 65 nM, respectively.
价 格:¥电议型 号:T6226产 地:中国大陆
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T62243Bepridil hydrochloride hydrate;化合物 Bepridil hydrochloride hydrateBepridil hydrochloride hydrate
Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a long-acting, non-selective antagonist of the calcium channel (Ca+channel), Bepridil hydrochloride hydrate is an inhibitor of the Na+,K+channel and an inhibitor of cardiac Na+/Ca2+ exchange (NCX1).
价 格:¥电议型 号:T62243产 地:中国大陆
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T62143LP-922761 hydrate;化合物 LP-922761 hydrateLP-922761 hydrate
LP-922761 hydrate is a selective, potent, orally active AAK1 inhibitor with IC50 values of 4.8 nM and 7.6 nM in enzyme and cellular assays, respectively. LP-922761 hydrate inhibits BMP-2 inducible protein kinase (BIKE) (IC50: 24 nM). 922761 hydrate has no significant effect on cellular GAK, opioids, adrenergic α2 or GABAa receptors.
价 格:¥电议型 号:T62143产 地:中国大陆
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T62039L-365260 hemihydrate;化合物 L-365260 hemihydrateL-365260 hemihydrate
L-365260 hemihydrate is a selective, orally active non-peptide gastrin and brain cholecystokinin receptor (CCK-B) antagonist, demonstrating competitive interaction with guinea pig stomach gastrin and brain CCK receptors and exhibiting inhibition constants (Kis) of 1.9 nM and 2.0 nM, respectively.
价 格:¥电议型 号:T62039产 地:中国大陆
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T6188Desvenlafaxine succinate hydrate;琥珀酸去甲文拉法辛O-Desmethylvenlafaxine succinate hydrate|||WY 45233 Succin
Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
价 格:¥电议型 号:T6188产 地:中国大陆
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T61764Zoledronic acid disodium tetrahydrate;化合物 Zoledronic acid disodium tetrahydrateZoledronic acid disod
Zoledronic Acid (Zoledronate) disodium tetrahydrate is a potent third-generation bisphosphonate (BP), exhibiting strong anti-resorptive activity. It effectively inhibits osteoclast differentiation and apoptosis, while also demonstrating anti-cancer properties [1].
价 格:¥电议型 号:T61764产 地:中国大陆
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T61741Azaphen dihydrochloride monohydrate;化合物 Azaphen dihydrochloride monohydrateAzaphen dihydrochloride m
Pipofezine(Azafen or Azaphen) is a potent inhibitor of the reuptake of serotonin. IC50 Value: Target: SSRIs Pipofezine is a tricyclic antidepressant (TCA) approved in Russia for the treatment ofdepression. In addition to its antidepressant action, pipofezine has sedative effects as well, indicating antihistamine activity.
价 格:¥电议型 号:T61741产 地:中国大陆
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T61725VU0463271 quarterhydrate;化合物 VU0463271 quarterhydrateVU0463271 quarterhydrate
VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].
价 格:¥电议型 号:T61725产 地:中国大陆
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T61708AZD 2066 hydrate;化合物 AZD 2066 hydrateAZD 2066 hydrate
AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].
价 格:¥电议型 号:T61708产 地:中国大陆
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T61627iMDK quarterhydrate;化合物 iMDK quarterhydrateiMDK quarterhydrate
iMDK quarterhydrate, a potent PI3K inhibitor, is effective in inhibiting the growth factor MDK (also known as midkine or MK) while demonstrating suppression of non-small cell lung cancer (NSCLC). In combination with a MEK inhibitor, iMDK quarterhydrate demonstrates cooperative inhibition of NSCLC without causing harm to normal cells and mice [1].
价 格:¥电议型 号:T61627产 地:中国大陆
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T61506NBI-31772 hydrate;化合物 NBI-31772 hydrateNBI-31772 hydrate
NBI-31772 hydrate is a powerful inhibitor of the interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). It acts as a nonpeptide ligand, effectively releasing bioactive IGF-I from the IGF-I/IGFBP-3 complex (Ki values for all six human subtypes range from 1-24 nM). This compound demonstrates significant anxiolytic and antidepressant-like effects [1] [2] [3].
价 格:¥电议型 号:T61506产 地:中国大陆