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T1185Rofecoxib;罗非考昔MK 966|||MK-0966;MK 966|||罗非昔布|||罗非考昔|||MK-0966
Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and potential antineoplastic properties. COX-related metabolic pathways may represent key regulators of cell proliferation and neo-angiogenesis. Some epithelial tumor cell types overexpress pro-angiogenic COX
价 格:¥电议型 号:T1185产 地:中国大陆
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T11798L-692429;化合物L-692429MK-0751;MK-0751
L-692429 (MK-0751) is a potent nonpeptidyl growth hormone secretagogue (GHS) agonist, a benzolactam derivative, which reverses the inhibition of GH secretion by glucocorticoids.L-692429 has a high affinity for the G protein-coupled receptor and can be used in the study of acromegaly and obesity. L-692429 has a high affinity for G protein-coupled receptor and can be used to study acromegaly and obesity.
价 格:¥电议型 号:T11798产 地:中国大陆
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T1137Clorsulon;氯舒隆L631529|||MK401;克洛索隆|||L631529|||MK401|||氯舒隆
Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.
价 格:¥电议型 号:T1137产 地:中国大陆
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T11310FMK-MEA;化合物 T11310FMK-MEA
FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.
价 格:¥电议型 号:T11310产 地:中国大陆
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T1131Ivermectin;伊维菌素MK-933;MK-933|||伊维菌素
Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
价 格:¥电议型 号:T1131产 地:中国大陆
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T11246Etoricoxib-d4;依托考昔 D4MK-0663 D4|||L-791456 D4|||Etoricoxib D4;MK-0663 D4|||依托考昔 D4|||L-791456 D4|||E
Etoricoxib D4 is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.Etoricoxib D4 is a deuterium labeled Etoricoxib.
价 格:¥电议型 号:T11246产 地:中国大陆
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T11193Enalaprilat-d5 sodium;依那普利拉钠 D5MK-422 D5 Sodium Salt|||Enalaprilat D5 Sodium Salt;MK-422 D5 Sodium S
Enalaprilat D5 Sodium Salt is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.
价 格:¥电议型 号:T11193产 地:中国大陆
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T1077Fluvoxamine maleate;氟伏沙明马来酸盐MK-264|||DU-23000 (maleate);氟伏沙明马来酸盐|||马来酸氟伏沙明|||MK-264|||DU-23000 (male
Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.
价 格:¥电议型 号:T1077产 地:中国大陆
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T10580BOC-D-FMK;3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯BOC-D-FMK
Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).
价 格:¥电议型 号:T10580产 地:中国大陆
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T10548Biotin-VAD-FMK;化合物 T10548Biotin-VAD-FMK
Biotin-VAD-FMK is a cell-permeable, irreversible biotin-labeled inhibitor of caspase. It is used to identify active caspases in cell lysates.
价 格:¥电议型 号:T10548产 地:中国大陆
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T1023Cefoxitin sodium;头孢西丁钠Cenomycin|||MK-306|||Betacef|||Merxin;Cenomycin|||MK-306|||头孢西丁钠|||Betacef|||M
Cefoxitin sodium (Betacef) is a semisynthetic cephamycin antibiotic resistant to beta-lactamase.
价 格:¥电议型 号:T1023产 地:中国大陆
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T0808Diflunisal;二氟尼柳Flovacil|||Dolobid|||MK-647|||Fluniget|||Dolobis;Flovacil|||二氟尼柳|||Dolobid|||MK-647||
Diflunisal (Dolobid) is a cyclooxygenase (COX) Inhibitor, used as an anti-inflammatory analgesic.
价 格:¥电议型 号:T0808产 地:中国大陆
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T0706Lisinopril dihydrate;赖诺普利二水合物Lisinopril|||Renacor|||MK-521 (dihydrate);Lisinopril|||Renacor|||赖诺普利二水
Lisinopril dihydrate (MK-521) is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
价 格:¥电议型 号:T0706产 地:中国大陆
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T0687Simvastatin;辛伐他汀MK-0733|||MK 733;辛伐他汀|||MK-0733|||MK 733
Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovascular disease.
价 格:¥电议型 号:T0687产 地:中国大陆
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T0505Methyldopa;甲基多巴L-(-)-α-Methyldopa|||MK-351;L-(-)-α-Methyldopa|||MK-351|||甲基多巴
Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or sympatholytic.
价 格:¥电议型 号:T0505产 地:中国大陆
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T0488Finasteride;非那雄胺MK-906;非那雄胺|||MK-906
Finasteride (MK-906) is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
价 格:¥电议型 号:T0488产 地:中国大陆
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T0459Sulindac;舒林酸Arthrocine|||MK-231|||Clinoril|||Sulindac sulfoxide;Arthrocine|||MK-231|||舒林酸|||Clinoril
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cyclic guanosine monophosphate-phosphodiesterase (cGMP-PDE), an enzyme that inhibits the normal apoptosis signal pathway; this inhibition permits the apoptotic signal pathway to proceed unopposed, resulting in apoptotic cell death.
价 格:¥电议型 号:T0459产 地:中国大陆
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T0242LSitagliptin phosphate monohydrate;西他列汀磷酸盐一水合物MK-0431|||MK-0431 phosphate monohydrate;MK-0431|||MK-04
Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.
价 格:¥电议型 号:T0242L产 地:中国大陆
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T0242Sitagliptin;西格列汀MK0431;西他列汀|||MK0431|||西格列汀
Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedione for treatment of type 2 diabetes mellitus. The drug can competitively inhibit a protein/enzyme and DPP-4, that leads to an incremental amount of active incretins (GLP-1 and GIP), the diminished amount of release of glucagon and increased release of insulin.
价 格:¥电议型 号:T0242产 地:中国大陆
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T0215Losartan potassium;氯沙坦钾DuP-753 potassium|||MK 954|||DuP 753;DuP-753 potassium|||洛沙坦钾|||氯沙坦钾|||MK 954
Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.
价 格:¥电议型 号:T0215产 地:中国大陆