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  • T62649HDAC-IN-34；化合物 HDAC-IN-34HDAC-IN-34

    HDAC-IN-34 (compound 27) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.022 μM) and HDAC6 (IC50: 0.45 μM). HDAC-IN-34 can bind to DNA and cause DNA damage. HDAC-IN-34 exhibits a significant anti-proliferative effect on HCT-116 cells (IC50: 1.41 μM).

    价 格：￥电议型 号：T62649产 地：中国大陆

  • T62633NTPDase-IN-3；化合物 NTPDase-IN-3NTPDase-IN-3

    NTPDase-IN-3 (Compound 5e), an inhibitor of NTPDase, exhibits IC50 values of 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), and 1.07 μM (NTPDase2). It is utilized in cancer and thrombosis research [1].

    价 格：￥电议型 号：T62633产 地：中国大陆

  • T62615ALK5-IN-30；化合物 ALK5-IN-30ALK5-IN-30

    ALK5-IN-30 (EX-07) is a potent inhibitor of ALK with inhibitory effects on ALK5 (IC50< 10 nM) and TGFβ-R1 (IC50< 10 nM).

    价 格：￥电议型 号：T62615产 地：中国大陆

  • T62599GRK5-IN-3；化合物 GRK5-IN-3GRK5-IN-3

    GRK5-IN-3 is a covalent inhibitor of G protein-coupled receptor kinase 5 (GRK5).GRK5-IN-3 significantly inhibits GRK5 (IC50: 0.22 μM) and GRK6 (IC50: 0.41 μM).

    价 格：￥电议型 号：T62599产 地：中国大陆

  • T62597TEAD-IN-3；化合物 TEAD-IN-3TEAD-IN-3

    TEAD-IN-3 (compound I-177) is a potent inhibitor of the TEAD transcription factor, which can be used to study proliferative diseases such as cancer.

    价 格：￥电议型 号：T62597产 地：中国大陆

  • T62580PI3K-IN-37；化合物 PI3K-IN-37PI3K-IN-37

    PI3K-IN-37 (Example 84.1) is an inhibitor of PI3K α (IC50: 6 nM), PI3K β (IC50: 8 nM) and PI3K δ (IC50: 4 nM). PI3K-IN-37 inhibits mTOR with an IC50 value of 4 nM.

    价 格：￥电议型 号：T62580产 地：中国大陆

  • T62469RSV/IAV-IN-3；化合物 RSV/IAV-IN-3RSV/IAV-IN-3

    RSV/IAV-IN-3 (compound 14´i) is a dual inhibitor of respiratory syncytial virus (RSV) (EC50: 2.92 μM) and influenza A virus (IAV) (EC50: 1.90 μM). RSV/IAV-IN-3 significantly inhibited luciferase activity in a dose-dependent manner (EC50: 3.89 μM). RSV/IAV-IN-3 inhibited IAV infection and RdRp activity, and inhibited IAV and RSV replication during the post-entry phase.

    价 格：￥电议型 号：T62469产 地：中国大陆

  • T62454Galectin-3-IN-1；化合物 Galectin-3-IN-1Galectin-3-IN-1

    Galectin-3-IN-1 (Compound 1) is a potent inhibitor of polyvalent galactose lectin-3 (Gal-3). Galectin-3 is involved in many metabolic processes associated with cancer.

    价 格：￥电议型 号：T62454产 地：中国大陆

  • T62395ALK5-IN-32；化合物 ALK5-IN-32ALK5-IN-32

    ALK5-IN-32 is a selective inhibitor of ALK-5 (10 nM

    价 格：￥电议型 号：T62395产 地：中国大陆

  • T62394ALK5-IN-31；化合物 ALK5-IN-31ALK5-IN-31

    ALK5-IN-31 is a selective inhibitor of ALK-5 (IC50≤10 nM) and also inhibits TGF-β-induced SMAD signalling.ALK5-IN-31 has the potential to inhibit tumour growth in vivo.ALK5-IN-31 can be used in the study of proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis).

    价 格：￥电议型 号：T62394产 地：中国大陆

  • T62392PI3K-IN-34；化合物 PI3K-IN-34PI3K-IN-34

    PI3K-IN-34 (Compound 6g) is a highly selective inhibitor of PI3K that acts on PI3K-α (IC50: 11.73 μM), PI3K-β (IC50: 6.09 μM) and PI3K-δ (IC50: 11.18 μM). PI3K-IN-34 can be used to study leukaemia.

    价 格：￥电议型 号：T62392产 地：中国大陆

  • T62375SARS-CoV-2 nsp13-IN-3；化合物 SARS-CoV-2 nsp13-IN-3SARS-CoV-2 nsp13-IN-3

    SARS-CoV-2 nsp13-IN-3 (Compound C3) is a small molecule inhibitor of SARS-CoV-2 non-structural protein 13 (nsp13) that acts on nsp13 ssDNA+ATPase (IC50: 32 μM).

    价 格：￥电议型 号：T62375产 地：中国大陆

  • T62344MIF-IN-3；化合物 MIF-IN-3MIF-IN-3

    MIF-IN-3 is an inhibitor of migration inhibitory factor (MIF), which can be used in the study of immunoinflammation-related diseases.

    价 格：￥电议型 号：T62344产 地：中国大陆

  • T62336BChE-IN-3；化合物 BChE-IN-3BChE-IN-3

    BChE-IN-3 is a selective, selective, time-dependent, pseudo-irreversible inhibitor of BChE butyrylcholinesterase (IC50: 56.9 nM).BChE-IN-3 exhibits borderline reversible (time-independent) inhibition of AChE acetylcholinesterase.

    价 格：￥电议型 号：T62336产 地：中国大陆

  • T62315HPK1-IN-30；化合物 HPK1-IN-30HPK1-IN-30

    HPK1-IN-30 is a potent inhibitor of HPK1. HPK1-IN-30 has potential for cancer disease research.

    价 格：￥电议型 号：T62315产 地：中国大陆

  • T62276Factor B-IN-3；化合物 Factor B-IN-3Factor B-IN-3

    Factor B-IN-3 is a potent inhibitor of complement factor B. Factor B-IN-3 can be used to study inflammatory and immune-related diseases.

    价 格：￥电议型 号：T62276产 地：中国大陆

  • T62272TRPC6-IN-3；化合物 TRPC6-IN-3TRPC6-IN-3

    TRPC6-IN-3 (compound 17) is an orally active inhibitor of the transient receptor potential C6 ion channel (TRPC6), which regulates intracellular calcium concentration and also regulates cation fluxes including calcium and sodium ions to modulate membrane potential.

    价 格：￥电议型 号：T62272产 地：中国大陆

  • T62236Steroid sulfatase/17β-HSD1-IN-3；化合物 Steroid sulfatase/17β-HSD1-IN-3Steroid sulfatase/17β-HSD1-IN-3

    Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-3 can be used to study endometriosis and other estrogen-dependent diseases.

    价 格：￥电议型 号：T62236产 地：中国大陆

  • T62234JAK3/BTK-IN-3；化合物 JAK3/BTK-IN-3JAK3/BTK-IN-3

    JAK3/BTK-IN-3 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets in autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway has a synergistic effect and JAK3/BTK-IN-3 has shown potential for the investigation of JAK3 kinases and/or BTK-related diseases.

    价 格：￥电议型 号：T62234产 地：中国大陆

  • T62220DGAT1-IN-3；化合物 DGAT1-IN-3DGAT1-IN-3

    DGAT1-IN-3 is a selective, potent, orally active DGAT-1 inhibitor that inhibits human DGAT-1 (IC50: 38 nM) and rat DGAT-1 (IC50: 120 nM).DGAT1-IN-3 can be used in studies of obesity, dyslipidemia and metabolic syndrome.

    价 格：￥电议型 号：T62220产 地：中国大陆

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