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T72753RSV604 racemate；化合物 RSV604 racemateA-60444 racemate；A-60444 racemate
RSV604 (A-60444) racemate, a racemic mixture, exhibits lower potency against strains of respiratory syncytial virus (RSV) compared to its S-isomer.
价 格：￥电议型 号：T72753产 地：中国大陆
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T72718SARS-CoV-2-IN-36；化合物 SARS-CoV-2-IN-36SARS-CoV-2-IN-36
SARS-CoV-2-IN-36 is a potent inhibitor of SARS-CoV-2 Mpro (SARS-CoV), demonstrating an IC50 of 2.37 μM and a Kd of 1.19 μM in enzymatic assays. This compound exhibits antiviral activity against SARS-CoV-2 variants UC-1074, RG2674, and NVDBB-2220 in Vero cells.
价 格：￥电议型 号：T72718产 地：中国大陆
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T72683PRRSV/CD163-IN-1；化合物 PRRSV/CD163-IN-1PRRSV/CD163-IN-1
PRRSV/CD163-IN-1, a PRRSV/CD163 inhibitor, effectively blocks the interaction between the PRRSV glycoproteins (GP2a or GP4) and the CD163-SRCR5 domain, making it a valuable tool for porcine reproductive and respiratory syndrome (PRRS) research.
价 格：￥电议型 号：T72683产 地：中国大陆
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T72671SARS-CoV-2-IN-12；化合物 SARS-CoV-2-IN-12SARS-CoV-2-IN-12
SARS-CoV-2-IN-12, a potent inhibitor of the SARS-CoV-2-related 3C-like protease (K_i=32.1 pM), plays a crucial role in preventing SARS-CoV-2 viral replication, showcasing potential significance in COVID-19 research.
价 格：￥电议型 号：T72671产 地：中国大陆
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T72669Loxoprofenol-SRS；化合物 Loxoprofenol-SRSLoxoprofenol-SRS
Loxoprofenol-SRS, a new intravenous non-steroidal anti-inflammatory drug (NSAID) and the active metabolite of Loxoprofen, demonstrates significantly enhanced anti-inflammatory and analgesic (pain-relieving) effects.
价 格：￥电议型 号：T72669产 地：中国大陆
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T7263SMS2-IN-2；化合物SMS2-IN-2SMS2 inhibitors；SMS2 inhibitors
SMS2-IN-2 (SMS2 inhibitors) is a potent, selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, (IC50s of 100 and 56 μM for SMS2 and SMS1, respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
价 格：￥电议型 号：T7263产 地：中国大陆
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T72581SARS-CoV MPro-IN-2；化合物 SARS-CoV MPro-IN-2SARS-CoV MPro-IN-2
SARS-CoV MPro-IN-2 effectively inhibits the SARS-CoV-2 main protease (M pro), crucial for the virus´s replication and transcription in host cells, with an IC50 value of 72.07 nM. Given its significant role in processing viral polyproteins, M pro is regarded as a key target in drug discovery efforts. Consequently, SARS-CoV MPro-IN-2 holds promise for COVID-19 research.
价 格：￥电议型 号：T72581产 地：中国大陆
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T72514MRS2279 diammonium；化合物 MRS2279 diammoniumMRS2279 diammonium
MRS2279 diammonium, a selective and high-affinity P2Y1 receptor antagonist, exhibits a Ki value of 2.5 nM and an IC50 value of 51.6 nM. It competitively inhibits ADP-promoted platelet aggregation, demonstrating a pKb value of 8.05.
价 格：￥电议型 号：T72514产 地：中国大陆
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T72451SARS-CoV-2 Mpro-IN-6；化合物 SARS-CoV-2 Mpro-IN-6SARS-CoV-2 Mpro-IN-6
SARS-CoV-2 Mpro-IN-6 is a selective, covalent, and irreversible inhibitor of SARS-CoV-2 main protease (Mpro), exhibiting an inhibition concentration (IC50) of 0.18 μM. It does not inhibit human cathepsins B, F, K, and L or caspase 3.
价 格：￥电议型 号：T72451产 地：中国大陆
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T72447SARS-CoV-2 Mpro-IN-5；化合物 SARS-CoV-2 Mpro-IN-5SARS-CoV-2 Mpro-IN-5
SARS-CoV-2 Mpro-IN-5 is a dual inhibitor targeting Main Protease (M Pro) and Cathepsin L (CatL) with IC50 values of 1800 nM and 145 nM, respectively. This compound demonstrates antiviral activity by inhibiting SARS-CoV-2 replication in hACE2 expressing A549 cells, with an IC50 value of 14.7 nM.
价 格：￥电议型 号：T72447产 地：中国大陆
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T72446SARS-CoV-2 Mpro-IN-4；化合物 SARS-CoV-2 Mpro-IN-4SARS-CoV-2 Mpro-IN-4
SARS-CoV-2 Mpro-IN-4 is a dual inhibitor targeting Main Protease (M Pro) and Cathepsin L (CatL), exhibiting inhibition concentrations (IC50) of 900 nM and 60 nM, respectively. It demonstrates antiviral activity by effectively blocking SARS-CoV2 replication in hACE2-expressing A549 cells with an IC50 value of 8.2 nM.
价 格：￥电议型 号：T72446产 地：中国大陆
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T72395CB1 inverse agonist 2；化合物 CB1 inverse agonist 2CB1 inverse agonist 2
CB1 Inverse Agonist 2, an orally active compound, serves as an inverse agonist for the Cannabinoid Receptor CB1. It effectively counteracts the hypothermia and anorexia induced by CP55940 in mouse models.
价 格：￥电议型 号：T72395产 地：中国大陆
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T72371SARS-CoV-2 3CLpro-IN-7；化合物 SARS-CoV-2 3CLpro-IN-7SARS-CoV-2 3CLpro-IN-7
SARS-CoV-2 3CLpro-IN-7 is a reversible covalent inhibitor of the SARS-CoV-2 3CL protease, exhibiting an inhibitory concentration (IC50) value of 1.4 ?M.
价 格：￥电议型 号：T72371产 地：中国大陆
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T72370SARS-CoV-2 3CLpro-IN-6；化合物 SARS-CoV-2 3CLpro-IN-6SARS-CoV-2 3CLpro-IN-6
SARS-CoV-2 3CLpro-IN-6 is a reversible covalent inhibitor targeting the SARS-CoV-2 3CL protease, demonstrating potent inhibitory activity with an IC50 of 4.9 μM. It is utilized in the research of coronavirus disease 2019 (COVID-19).
价 格：￥电议型 号：T72370产 地：中国大陆
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T72364SARS-CoV-2 3CLpro-IN-5；化合物 SARS-CoV-2 3CLpro-IN-5SARS-CoV-2 3CLpro-IN-5
SARS-CoV-2 3CLpro-IN-5 is a covalent inhibitor targeting the 3C-like protease (3CLpro), exhibiting potent inhibitory activity with an IC50 of 3.8 nM and demonstrating 9.0% oral bioavailability (BA). It is utilized in the research of coronavirus disease 2019 (COVID-19) [1].
价 格：￥电议型 号：T72364产 地：中国大陆
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T72313SARS-CoV-2 3CLpro-IN-11；化合物 SARS-CoV-2 3CLpro-IN-11SARS-CoV-2 3CLpro-IN-11
SARS-CoV-2 3CLpro-IN-11(11d) is a broad-spectrum antiviral compound that effectively inhibits the SARS-CoV-2 3CL protease, achieving an IC50 of 140 nM. Additionally, it exhibits inhibitory activity against SARS-CoV-1 and MERS-CoV with IC50 values of 240 nM and 70 nM, respectively.
价 格：￥电议型 号：T72313产 地：中国大陆
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T72312SARS-CoV-2 3CLpro-IN-10；化合物 SARS-CoV-2 3CLpro-IN-10SARS-CoV-2 3CLpro-IN-10
SARS-CoV-2 3CLpro-IN-10(5d) is a potent inhibitor of the SARS-CoV-2 3CL protease, exhibiting an IC50 value of 190 nM, and demonstrates varied efficiency against other coronaviruses with IC50 values of 790 nM for SARS-CoV-1 and 70 nM for MERS-CoV, indicating broad-spectrum antiviral activity.
价 格：￥电议型 号：T72312产 地：中国大陆
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T72254RORγt inverse agonist 26；化合物 RORγt inverse agonist 26RORγt inverse agonist 26
RORγt inverse agonist 26, a potent reverse agonist of RORγt, effectively modulates Th17 cell differentiation and suppresses IL-17 production. This compound shows promising potential for researching inflammation and autoimmune diseases.
价 格：￥电议型 号：T72254产 地：中国大陆
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T72252RORγt inverse agonist 14；化合物 RORγt inverse agonist 14RORγt inverse agonist 14
RORγt inverse agonist 14 (8e) is a potent, selective, and orally active compound with an EC50 of 2.5 nM, exhibiting anti-inflammatory activity. It is employed in researching rheumatoid arthritis and psoriasis [1].
价 格：￥电议型 号：T72252产 地：中国大陆
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T72248MRS2768 tetrasodium salt；化合物 MRS2768 tetrasodium saltMRS2768 tetrasodium salt
MRS2768 tetrasodium salt, a moderately potent and selective agonist of the P2Y2 receptor, exhibits a protective effect against ischemic damage in cardiomyocytes both in vivo and in vitro.
价 格：￥电议型 号：T72248产 地：中国大陆
