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  • T62609MK-2206；化合物 MK-2206MK-2206

    MK-2206 is an orally active, highly selective, metabotropic Akt inhibitor that acts on Akt1 (IC50: 8 nM), Akt2 (IC50: 12 nM) and Akt3 (IC50: 65 nM). Many breast cancer cell lines, PIK3CA mutants and PTEN-losing cell lines are sensitive to MK-2206, which has anti-cancer effects.

    价 格：￥电议型 号：T62609产 地：中国大陆

  • T62608Sovesudil hydrochloride；化合物 Sovesudil hydrochlorideSovesudil hydrochloride

    Sovesudil (PHP-201) hydrochloride is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor that acts on ROCK I (IC50: 3.7 nM) and ROCK II (IC50: 2.3 nM). Sovesudil hydrochloride is capable of lowering IOP without causing congestion.

    价 格：￥电议型 号：T62608产 地：中国大陆

  • T62607FLT3-IN-15；化合物 FLT3-IN-15FLT3-IN-15

    FLT3-IN-15 is an orally active and potent FLT3 inhibitor, capable of acting on FLT3 (IC50: 0.87 nM) and FLT3/D835Y (IC50: 0.32 nM).

    价 格：￥电议型 号：T62607产 地：中国大陆

  • T62606ALOX15-IN-2；化合物ALOX15-IN-2ALOX15-IN-2

    ALOX15-IN-2 is a potent inhibitor of ALOX15 linoleate oxygenase activity, inhibiting the oxidation of linoleic acid (LA) and arachidonic acid (AA), the immediate homologs of ALOX15, with IC50s of 1.55 and 2.79 μM, respectively.

    价 格：￥电议型 号：T62606产 地：中国大陆

  • T62605CDK4/6-IN-13；化合物 CDK4/6-IN-13CDK4/6-IN-13

    Compounds 10B and 10C, functioning as cdk4/6 inhibitors, demonstrated low nanomolar activity, optimal antiproliferative effects, excellent metabolic properties, and acceptable pharmacokinetics targeting cdk4/6.

    价 格：￥电议型 号：T62605产 地：中国大陆

  • T62604Flunisolide hemihydrate；化合物 Flunisolide hemihydrateFlunisolide hemihydrate

    Flunisolide hemihydrate is a corticosteroid, an orally active Glucocorticoid receptor activator with anti-inflammatory effects. flunisolide hemihydrate induces apoptosis in eosinophils and can be used in asthma or rhinitis, inflammatory diseases. Can be used in studies related to asthma or rhinitis, inflammation.

    价 格：￥电议型 号：T62604产 地：中国大陆

  • T62603NVP-BBD130；化合物 NVP-BBD130NVP-BBD130

    NVP-BBD130 is a stable, ATP-competitive, potent, orally active inhibitor of PI3K and mTOR.

    价 格：￥电议型 号：T62603产 地：中国大陆

  • T62602Anticancer agent 49；化合物 Anticancer agent 49Anticancer agent 49

    Anticancer agent 49 (compound 69) is a broad-spectrum anticancer agent with anti-proliferative activity. anticancer agent 48 inhibits microtubule protein aggregation and has in vivo antitumour activity. anticancer agent 48 has potential for solid tumour and haematological tumour studies. anticancer agent 49 is a broad-spectrum anticancer agent with anti-proliferative activity.

    价 格：￥电议型 号：T62602产 地：中国大陆

  • T62601Anticancer agent 48；化合物 Anticancer agent 48Anticancer agent 48

    Anticancer agent 48 (compound 48) is a broad-spectrum anticancer agent with anti-proliferative activity. anticancer agent 48 inhibits microtubule protein polymerisation and has anti-tumour activity in vivo. anticancer agent 48 has potential for solid tumour and haematological tumour studies.

    价 格：￥电议型 号：T62601产 地：中国大陆

  • T62600RYL-552S；化合物 RYL-552SRYL-552S

    RYL-552S is a drug-resistant strain of Plasmodium falciparum that effectively kills the asexual blood stage of the parasite in vitro.

    价 格：￥电议型 号：T62600产 地：中国大陆

  • T6260AMG-208；化合物AMG-208AMG 208；AMG 208

    AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.

    价 格：￥电议型 号：T6260产 地：中国大陆

  • T62599GRK5-IN-3；化合物 GRK5-IN-3GRK5-IN-3

    GRK5-IN-3 is a covalent inhibitor of G protein-coupled receptor kinase 5 (GRK5).GRK5-IN-3 significantly inhibits GRK5 (IC50: 0.22 μM) and GRK6 (IC50: 0.41 μM).

    价 格：￥电议型 号：T62599产 地：中国大陆

  • T62598Pitavastatin sodium；化合物 Pitavastatin sodiumPitavastatin sodium

    Pitavastatin (NK-104) sodium is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase and a potent inducer of the hepatocyte low-density lipoprotein cholesterol (LDL-C) receptor. pitavastatin sodium inhibits acetate synthesis of cholesterol in HepG2 cells ( Pitavastatin sodium exhibits anti-atherogenic, anti-osteoarthritic, anti-asthmatic, anti-tumour, neuroprotective, hepatoprotective and nephroprotective effects.

    价 格：￥电议型 号：T62598产 地：中国大陆

  • T62597TEAD-IN-3；化合物 TEAD-IN-3TEAD-IN-3

    TEAD-IN-3 (compound I-177) is a potent inhibitor of the TEAD transcription factor, which can be used to study proliferative diseases such as cancer.

    价 格：￥电议型 号：T62597产 地：中国大陆

  • T62596BRL-15572 hydrochloride；化合物 BRL-15572 hydrochlorideBRL-15572 hydrochloride

    BRL-15572 hydrochloride is a selective antagonist of h5-HT1D and shows high affinity for the h5-HT1D receptor. BRL-15572 hydrochloride may be a useful pharmacological agent for characterizing h5-HT1D receptor-mediated responses.

    价 格：￥电议型 号：T62596产 地：中国大陆

  • T62595G092；化合物 G092G092

    G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter protein. G092 has potential for antibacterial drug research.

    价 格：￥电议型 号：T62595产 地：中国大陆

  • T62594THR-β agonist 2；化合物 THR-β agonist 2THR-β agonist 2

    THR-β agonist 2 is a potent agonist of THR-β. THR-β agonist 2 has potential for studies of metabolic diseases (e.g. obesity, hyperlipidaemia, hypercholesterolaemia, diabetes and other conditions such as steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis and other related conditions and diseases).

    价 格：￥电议型 号：T62594产 地：中国大陆

  • T62593Xininurad；化合物 XininuradXininurad

    Xininurad (XNW3009) is a urate transporter (URAT) inhibitor.

    价 格：￥电议型 号：T62593产 地：中国大陆

  • T62592(R)-Gyramide A hydrochloride；化合物 (R)-Gyramide A hydrochloride(R)-Gyramide A hydrochloride

    (R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts superhelical activity (IC50: 875 μM). (R)-Gyramide A hydrochloride exhibits antibacterial activity against Pseudomonas aeruginosa E. coli with MIC values of 10-80 μM.(R)-Gyramide A hydrochloride does not affect the closely related enzyme topoisomerase IV.

    价 格：￥电议型 号：T62592产 地：中国大陆

  • T62591SBE13；化合物 SBE13SBE13

    SBE13 is a selective and potent inhibitor of Plk1 (IC50: 200 pM). SBE13 has a weak effect on Plk2 or Plk3 with IC50 values of >66 μM and 875 nM respectively.

    价 格：￥电议型 号：T62591产 地：中国大陆

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