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T26862BMS-902483;化合物 T26862BMS-902483
BMS-902483 is a potent α7 partial agonist. BMS-902483 improved cognition in preclinical rodent models. BMS-902483 showed FLIR α7 EC50=9.3nM; α7 Electrophysiology, rat; Area EC50 = 140 nM; Peak, Area (Ymax %) = 40, 54. 5-HT3A IC50 = 480 nm.
价 格:¥电议型 号:T26862产 地:中国大陆
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T26861BMS-817399;化合物BMS-817399BMS817399;BMS817399
BMS-817399 is an orally active antagonist of CCR1 with IC50s of binding affinity and chemotaxis inhibition potencies and can be used in studies about rheumatoid arthritis.
价 格:¥电议型 号:T26861产 地:中国大陆
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T26860BMS-814580;化合物 T26860BMS-814580
BMS-814580 is a potent and selective functional antagonist (Kb = 117 nM) of human MCHR1. BMS-814580 exhibits potent binding affinity (Ki = 17 nM) for human MCHR1. BMS-814580 also exhibits potent binding affinities for cynomolgus monkey and rat MCHR1 (Ki of 4.9 and 11.5 nM, respectively). MCHR1 antagonist demonstrates reduction in feeding and body weight in rats and mice.
价 格:¥电议型 号:T26860产 地:中国大陆
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T26859BMS-8;化合物BMS-8BMS-8
BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.
价 格:¥电议型 号:T26859产 地:中国大陆
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T26858BMS-770767;化合物 T26858BMS-770767
BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11?-HSD1) inhibitor.
价 格:¥电议型 号:T26858产 地:中国大陆
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T26857BMS-767778;化合物 T26857BMS-767778
BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.
价 格:¥电议型 号:T26857产 地:中国大陆
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T26856BMS-764459;化合物 T26856BMS-764459
BMS-764459 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).
价 格:¥电议型 号:T26856产 地:中国大陆
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T26855BMS-665053;化合物 T26855BMS665053;BMS665053
BMS-665053 is a corticotropin-releasing factor-1 (CRF1) receptor antagonist (IC50 = 1.0 nM). BMS-665053)11 is a potent inhibitor of CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells (IC50 = 4.9 nM). In addition, BMS-665053 is efficacious in the Defensive Withdrawal model of anxiety in rats and has low in vivo clearance (Cl = 17 mL/min/kg, t? = 7.8 h) in rats.
价 格:¥电议型 号:T26855产 地:中国大陆
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T26854BMS641;化合物BMS641BMS-641|||BMS-209641|||BMS 641;BMS-641|||BMS-209641|||BMS 641
BMS641 (BMS-209641) is a selective and potent RARβ agonist.BMS641 has a high affinity for RARβ and synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.
价 格:¥电议型 号:T26854产 地:中国大陆
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T26852BMS-605541;化合物BMS-605541BMS605541|||BMS 605541;BMS605541|||BMS 605541
BMS-605541 is a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) kinase activity(Ki=49 nM).
价 格:¥电议型 号:T26852产 地:中国大陆
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T26851BMS-561390;化合物 T26851DPC083|||DPC 083|||DPC-083;DPC083|||DPC 083|||DPC-083
BMS-561390, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
价 格:¥电议型 号:T26851产 地:中国大陆
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T26850BMS-538305 HCl;化合物 T26850BMS-538305|||BMS538305|||BMS 538305|||BMS-538305 hydrochloride;BMS-538305||
BMS-538305 is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP-IV).
价 格:¥电议型 号:T26850产 地:中国大陆
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T26849BMS-457;化合物 T26849BMS-457
BMS-457 is a potent, CCR1-selective antagonist.
价 格:¥电议型 号:T26849产 地:中国大陆
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T26848BMS-433771 free base;化合物 T26848BMS-433771|||BMS 433771|||BMS433771;BMS-433771|||BMS 433771|||BMS4337
BMS-433771, a novel inhibitor of respiratory syncytial virus (RSV), binds the RSV F glycoprotein and inhibits membrane fusion.
价 格:¥电议型 号:T26848产 地:中国大陆
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T26847BMS-281384;化合物 T26847BMS-281384
BMS-281384 is a highly potent, phosphodiesterase 5 (PDE 5)-selective inhibitor.
价 格:¥电议型 号:T26847产 地:中国大陆
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T26846BMS270394;化合物 T26846BMS 189961|||BMS-270394|||BMS 270394;BMS 189961|||BMS-270394|||BMS 270394
BMS270394 is an agonist of nuclear retinoic acid receptor (RAR-γ).
价 格:¥电议型 号:T26846产 地:中国大陆
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T26845BMS-250749;化合物 T26845BMS 250749|||BMS250749;BMS 250749|||BMS250749
BMS-250749 is a fluoroglycosylated fluoroindolocarbazole, it has antitumor activity.
价 格:¥电议型 号:T26845产 地:中国大陆
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T26844BMS-199945;化合物 T26844BMS199945|||BMS 199945;BMS199945|||BMS 199945
BMS-199945 is an Influenza H1N1 Virus inhibitor.
价 格:¥电议型 号:T26844产 地:中国大陆
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T26843BMS-199264 hydrochloride;化合物 T26843BMS-199264 hydrochloride
BMS-199264 hydrochloride potently inhibits the ATP hydrolase activity of mitochondrial F1F0 ATP synthase.
价 格:¥电议型 号:T26843产 地:中国大陆
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T26842Bms 188107;化合物 T26842Bms188107|||Bms-188107;Bms188107|||Bms-188107
Bms 188107 is a calcium antagonist, it has cardioprotective effects.
价 格:¥电议型 号:T26842产 地:中国大陆