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T22681CP 135807;化合物 T22681CP 135807
CP 135807 is a 5-HT1D receptor agonist.
价 格:¥电议型 号:T22681产 地:中国大陆
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T22680CP-100356 hydrochloride;CP-100356 盐酸盐CP-100356 HCl|||CP 100356 hydrochloride;CP-100356 HCl|||CP 1003
CP-100356 hydrochloride is an orally active and low micromolar dual inhibitor of MDR1 (P-gp) and BCRP, a nucleotide-derived substrate analogue with inhibitory effects on MDR1-mediated Calcein-AM transporter and BCRP-mediated Prazosin transporter.CP-100356 Inhibits OATP1B1, induces stomatal opening in the dark.
价 格:¥电议型 号:T22680产 地:中国大陆
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T22595B2;奥司他韦杂质B(2-叠氮杂合物)Linazolamide intermediate B impurity 2|||CPNQ|||5-[4-(4-Chlorobenzoyl)-1-piperazi
B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington´s disease and Parkinson´s disease
价 格:¥电议型 号:T22595产 地:中国大陆
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T225368-pCPT-2-O-Me-cAMP-AM;化合物 T225368 pCPT 2 O Me cAMP AM|||8-pCPT-2-O-Me-cAMP-AM|||8pCPT2OMecAMPAM;8 pC
Epac activator
价 格:¥电议型 号:T22536产 地:中国大陆
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T225083-CPMT;化合物3-CPMTChlortropbenzyl hydrochloride|||3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabic
3-CPMT (FC-1) is a dopamine uptake inhibitor and a potent long-acting antihistaminic agent.
价 格:¥电议型 号:T22508产 地:中国大陆
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T224902,3-DCPE hydrochloride;化合物 T224902,3-DCPE hydrochloride
Induces p21 expression and S-phase arrest in cancer cells via ERK-mediated pathways. IC50 values are 0.89 and 12.6 μM for LoVo human colon cancer cell line and normal human fibroblasts respectively.
价 格:¥电议型 号:T22490产 地:中国大陆
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T224892’-MeCCPA;化合物2’-MeCCPA2-Chloro-N-cyclopentyl-2′-C-methyladenosine;2-Chloro-N-cyclopentyl-2′-C-methyl
2´-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR.2´-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM.2´-MeCCPA exhibits analgesic activity and can be used in the study of HCV.
价 格:¥电议型 号:T22489产 地:中国大陆
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T22488(1S,3R)-ACPD化合物 T22488(1S,3R) ACPD|||(1S,3R)ACPD
(1S,3R)-ACPD is a group I and II mGlu receptor agonist.
价 格:¥电议型 号:T22488产 地:中国大陆
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T22433Sulopenem硫培南CP-70429|||硫培南
Sulopenem, an orally active, potent inhibitor of beta-lactamase, is a parenteral penem antibiotic with broad-spectrum activities against Gram-negative and Gram-positive bacteria.
价 格:¥电议型 号:T22433产 地:中国大陆
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T22299CPI-455 HCl;化合物CPI-455 HClCPI-455 HCl
CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with targeted agents or standard chemotherapy.
价 格:¥电议型 号:T22299产 地:中国大陆
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T22298CPD3615-A5;化合物CPD3615-A5CPD3615-A5
CPD3615-A5 is an active chemical.
价 格:¥电议型 号:T22298产 地:中国大陆
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T220148-CPT-2Me-cAMP, sodium salt;化合物 T220148-CPT-2Me-cAMP, sodium salt
8-CPT-2Me-cAMP sodium is a sodium salt compound that selectively activates exchange proteins activated by cAMP (Epac). These Epac proteins are cAMP-sensitive guanine nucleotide exchange factors (GEFs) responsible for activating small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium specifically activates Epac1 with an EC50 value of 2.2 μM, while showing no activation of PKA with an EC50 value greater than 10 μM [1]. Additionally, 8-CPT-2Me-cAMP sodium stimulates the Epac-mediated release of calcium
价 格:¥电议型 号:T22014产 地:中国大陆
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T21996Zoniporide hydrochloride;化合物ZoniporideCP-597396 hydrochloride;CP-597396 hydrochloride
Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride shows an IC50 of 59 nM for NHE-1-dependent swelling of human platelets.
价 格:¥电议型 号:T21996产 地:中国大陆
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T21875CP-465022 (maleate);化合物 T21875CP-465022 (maleate)
CP-465022 Maleate is a potent, selective, noncompetitive AMPA receptor antagonist with anticonvulsant activity. It effectively counters the Kainate-induced response in rat cortical neurons, exhibiting an IC 50 of 25 nM. As such, CP-465022 Maleate presents a valuable instrument for studying the involvement of AMPA receptors in various physiological and pathophysiological processes [1] [2].
价 格:¥电议型 号:T21875产 地:中国大陆
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T217058-CPT-Cyclic AMP (sodium salt);化合物 T217058-CPT-Cyclic AMP (sodium salt)
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium functions dually as a selective activator of cyclic AMP-dependent protein kinase (PKA) and as a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA), demonstrating an inhibitory concentration (IC 50) of 0.9 μM. Additionally, this compound inhibits PDE III and PDE IV, while significantly activating Epac, showcasing its diverse pharmacological activities [1] [2].
价 格:¥电议型 号:T21705产 地:中国大陆
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T21648CP-31398 dihydrochloride;化合物CP 31398 dihydrochlorideCP 31398 dihydrochloride;CP 31398 dihydrochlorid
CP-31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53.
价 格:¥电议型 号:T21648产 地:中国大陆
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T21584CP 465022;CP 465022CP 465022
CP 465022 hydrochloride is a potent, and selective noncompetitive antagonist of AMPA receptor with anticonvulsant activity. CP 465022 hydrochloride inhibits Kainate-induced response with an IC50 of 25 nM in rat cortical neurons.
价 格:¥电议型 号:T21584产 地:中国大陆