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T1748Kartogenin;化合物KartogeninKGN;KGN
Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.
价 格:¥电议型 号:T1748产 地:中国大陆
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T17278YUKA1;化合物 T17278YUKA1
YUKA1 is a potent and cell-permeable Lysine demethylase 5A inhibitor (IC50: 2.66 μM) and less active on KDM5C (IC50, 7.12 μM). YUKA1 is inactive on KDM5B, KDM6A, or KDM6B.
价 格:¥电议型 号:T17278产 地:中国大陆
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T17227Vernakalant Hydrochloride;盐酸维那卡兰RSD1235 hydrochloride;RSD1235 hydrochloride
Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.
价 格:¥电议型 号:T17227产 地:中国大陆
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T16891SKA-121;化合物 T16891SKA-121
SKA-121 is a selective KCa3.1 activator (EC50s: 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively).
价 格:¥电议型 号:T16891产 地:中国大陆
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T16780Rodatristat;化合物 T16780KAR5417;KAR5417
Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).
价 格:¥电议型 号:T16780产 地:中国大陆
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T1677LMontelukast sodium孟鲁司特钠MK0476|||孟鲁司特钠
Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.
价 格:¥电议型 号:T1677L产 地:中国大陆
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T16779Rodatristat ethyl;化合物RVT-014|||KAR5585|||RVT-1201;RVT-014|||KAR5585|||RVT-1201
Rodatristat ethyl (KAR5585) is a first-of-its-kind orally active and potent tryptophan hydroxylase 1 (TPH1) inhibitor that significantly reduces 5-hydroxytryptamine (5-HT) levels and decreases pulmonary arterial hypertension (PAH) at low concentrations.
价 格:¥电议型 号:T16779产 地:中国大陆
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T1677Montelukast;孟鲁司特Singular;孟鲁司特|||Singular
Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.
价 格:¥电议型 号:T1677产 地:中国大陆
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T16523LPhiKan 083;化合物PhiKan 083PhiKan 083
PhiKan 083 is a carbazole derivative
价 格:¥电议型 号:T16523L产 地:中国大陆
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T16523PhiKan 083 hydrochloride化合物 T16523PhiKan 083 hydrochloride
PhiKan 083 hydrochloride is a carbazole derivative. Which binds to the surface cavity and stabilizes Y220C (Kd: 167 μM). It also a relative binding affinity (Kd) of 150 μM in Ln229 cells.
价 格:¥电议型 号:T16523产 地:中国大陆
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T16381Okadaic acid;冈田酸Okadaic acid
Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted from black sponges of the genus Halichondria. Okadaic acid eliminates metazoan symbionts/parasites by apoptosis.
价 格:¥电议型 号:T16381产 地:中国大陆
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T16326Cipargamin;化合物CipargaminKAE609|||NITD609;KAE609|||NITD609
Cipargamin (NITD609) is an effective antimalarial compound. It has an IC50 of appr 1 nM against P. falciparum.
价 格:¥电议型 号:T16326产 地:中国大陆
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T1625Lomefloxacin hydrochloride;盐酸洛美沙星Lomefloxacin HCl|||Okacyn|||Maxaquin;Lomefloxacin HCl|||盐酸洛美沙星|||Ok
Lomefloxacin hydrochloride (Okacyn) inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. Lomefloxacin Hydrochloride is the hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity.
价 格:¥电议型 号:T1625产 地:中国大陆
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T15647Tipelukast;泰鲁司特MN 001|||KCA 757;MN 001|||KCA 757
Tipelukast (KCA 757) is a novel orally available leukotriene receptor antagonist with anti-inflammatory activity that reduces fibrosis and down-regulates TIMP-1, type 1 collagen.Tipelukast is used in the study of asthma.
价 格:¥电议型 号:T15647产 地:中国大陆
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T15644KAT681;化合物 T15644T0681;T0681
KAT681 is a liver selective thyromimetic.
价 格:¥电议型 号:T15644产 地:中国大陆
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T15643Kainic acid红藻氨酸红藻氨酸
In the CNS, Kainic acid is an effective agonist at excitatory amino acid receptor subtypes.
价 格:¥电议型 号:T15643产 地:中国大陆
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T15642KAG-308;化合物 T15642KAG-308
KAG-308 is an effective selective and orally active agonist of the EP4 receptor (Ki: 2.57 nM and EC50: 17 nM for human EP4 receptor), more selective over EP1, EP2, EP3, and IP receptor. KAG-308 suppresses colitis and promotes histological mucosal healing, which potently inhibits TNF-α production.
价 格:¥电议型 号:T15642产 地:中国大陆
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T15556Ikarugamycin;斑鸠霉素Ikarugamycin
Ikarugamycin, an antibiotic, is an inhibitor of clathrin-mediated endocytosis (CME).
价 格:¥电议型 号:T15556产 地:中国大陆
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T1530Mitiglinide calcium hydrate;米格列奈钙KAD-1229 calcium hydrate|||Mitiglinide calcium|||S-21403 calcium hy
Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. Mitiglinide belongs to the meglitinide class of blood glucose-lowering drugs and is currently co-marketed in Japan by Kissei and Takeda.
价 格:¥电议型 号:T1530产 地:中国大陆
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T15286Flindokalner;化合物FlindokalnerBMS-204352;BMS-204352
Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner displays a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM) and acts as a negative modulator of GABAA receptors and it also shows anxiolytic efficacy in vivo.
价 格:¥电议型 号:T15286产 地:中国大陆