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T7535RGX-202胍基丙酸胍基丙酸|||β-GPA|||3-Guanidinopropionic Acid
RGX-202 (β-GPA) is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-activated protein kinase (AMPK), activating PPARγ coactivator 1α (PGC-1α).
价 格:¥电议型 号:T7535产 地:中国大陆
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T75169SRG-II-19F;化合物 SRG-II-19FSRG-II-19F
SRG-II-19F (dCym-JQ1), a BRDT BD1 (bromodomain1 of BRDT) degrader, is utilized to examine the regulatory influence of ClpC2 on the ClpC1P1P2 protease [1].
价 格:¥电议型 号:T75169产 地:中国大陆
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T7510Leucylarginylproline;化合物LeucylarginylprolineLeucylarginylproline
Leucylarginylproline is an inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM).
价 格:¥电议型 号:T7510产 地:中国大陆
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T750397,8-Dihydro-8-oxo-7-propargyl guanosine;化合物 7,8-Dihydro-8-oxo-7-propargyl guanosine7,8-Dihydro-8-oxo
7,8-Dihydro-8-oxo-7-propargyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1] .
价 格:¥电议型 号:T75039产 地:中国大陆
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T7495Hexa-D-arginine;化合物Hexa-D-arginineHexa-D-arginine
Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.
价 格:¥电议型 号:T7495产 地:中国大陆
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T7434Argipressin;精氨加压素Arg8-vasopressin|||Vasopressin|||AVP;Arg8-vasopressin|||Vasopressin|||醋酸精氨酸加压素|||精氨
Argipressin (Vasopressin) is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively.
价 格:¥电议型 号:T7434产 地:中国大陆
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T74192Z-Leu-Arg-AMC;化合物 Z-Leu-Arg-AMCZ-Leu-Arg-AMC
Z-Leu-Arg-AMC, a carboxybenzoyl (Z) leucine derivative featuring a 4-methylcoumarinyl-7-amide (AMC), serves as the active site for the cysteine proteinase trypanopain-Tb in Trypanosoma brucei brucei [1].
价 格:¥电议型 号:T74192产 地:中国大陆
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T74059Targaprimir-96 TFA;化合物 Targaprimir-96 TFATargaprimir-96 TFA
Targaprimir-96 TFA, a potent inhibitor of microRNA-96 (miR-96) processing, selectively reduces miR-96 production in cancer cells, thereby inducing apoptosis. This compound exhibits low nanomolar affinity binding to primary miR-96 (pri-miR-96), targeting it specifically in breast cancer cells while remaining inactive in normal breast cells [1].
价 格:¥电议型 号:T74059产 地:中国大陆
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T74040Boc-Gln-Ala-Arg-AMC hydrochloride;Boc-Gln-Ala-Arg-AMC盐酸盐Boc-Gln-Ala-Arg-AMC hydrochloride
Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorescent compound that serves as a substrate for trypsin and is also used to determine the protein hydrolysis activity of TMPRSS2.
价 格:¥电议型 号:T74040产 地:中国大陆
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T73907H-Arg-Lys-OH TFA;化合物 H-Arg-Lys-OH TFAH-Arg-Lys-OH TFA
H-Arg-Lys-OH TFA is a dipeptide formed from L-arginyl and L-lysine residues [1] .
价 格:¥电议型 号:T73907产 地:中国大陆
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T73870Arg-Gly-Asp-Ser TFA;化合物 Arg-Gly-Asp-Ser TFAArg-Gly-Asp-Ser TFA
Arg-Gly-Asp-Ser (TFA) is an integrin-binding sequence that serves to inhibit integrin receptor function by directly and specifically binding to pro-caspase-8, pro-caspase-9, and pro-caspase-3, without interacting with pro-caspase-1 [1].
价 格:¥电议型 号:T73870产 地:中国大陆
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T73688Insulin glargine;化合物 Insulin glargineInsulin glargine
Insulin glargine, a long-acting insulin analog, is utilized for the treatment of diabetes mellitus [1].
价 格:¥电议型 号:T73688产 地:中国大陆
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T73646Lys-[Des-Arg9]Bradykinin TFA;化合物 Lys-[Des-Arg9]Bradykinin TFALys-[Des-Arg9]Bradykinin TFA
Lys-[Des-Arg9]Bradykinin TFA is a naturally occurring kinin that serves as a potent and highly selective agonist for the bradykinin B1 receptor, demonstrating binding affinities (K i values) of 0.12 nM, 1.7 nM, and 0.23 nM for the human, mouse, and rabbit B1 receptors, respectively. This compound exhibits low inhibitory activity on B2 receptors [1] [2].
价 格:¥电议型 号:T73646产 地:中国大陆
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T73469SG2057;化合物 SG2057DRG16;DRG16
SG2057 (DRG16), a potent antitumor agent, is a pyrrolobenzodiazepine (PBD) dimer connected by a pentyldioxy linkage. This compound selectively binds to the minor groove of DNA, forming both interstrand and intrastrand cross-linked adducts, contributing to its high antitumor activity.
价 格:¥电议型 号:T73469产 地:中国大陆
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T73404Dalargin;化合物 DalarginDalargin
Dalargin, a potent δ-opioid receptor agonist, demonstrates efficacy in mitigating cell death induced by Gentamicin and exhibits nephroprotective effects against Gentamicin-induced kidney injury. Additionally, Dalargin possesses antiulcer activity [1] [2] [3].
价 格:¥电议型 号:T73404产 地:中国大陆
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T7339Angiotensin (1-7);化合物Angiotensin 1-7Ang-(1-7)|||Angiotensin 1-7|||ASP-ARG-VAL-TYR-ILE-HIS-PRO;Ang-(1
Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0.65 μM) with vasodilator and antiproliferative activities.
价 格:¥电议型 号:T7339产 地:中国大陆
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T73389RGT-068A;化合物 RGT-068ARGT-068A
RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor [1] .
价 格:¥电议型 号:T73389产 地:中国大陆
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T73196RGB-286638;化合物 RGB-286638RGB-286638
RGB-286638 is a multi-target CDK inhibitor that effectively hampers the kinase activity of a range of cyclin-CDK complexes, including cyclin T1-CDK9 (IC50 = 1 nM), cyclin B1-CDK1 (IC50 = 2 nM), cyclin E-CDK2 (IC50 = 3 nM), cyclin D1-CDK4 (IC50 = 4 nM), cyclin E-CDK3 (IC50 = 5 nM), and p35-CDK5 (IC50 = 5 nM). Additionally, it inhibits other kinases such as GSK-3β (IC50 = 3 nM), TAK1 (IC50 = 5 nM), Jak2 (IC50 = 50 nM), and MEK1 (IC50 = 54 nM), showcasing its versatile inhibitory potential.
价 格:¥电议型 号:T73196产 地:中国大陆
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T7300GDC-0575;化合物GDC-0575ARRY-575|||RG7741;ARRY-575|||RG7741
GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).
价 格:¥电议型 号:T7300产 地:中国大陆
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T7284Argipressin acetate (113-79-1(free base));醋酸精氨加压素Argipressin acetate (113-79-1(free base))
Vasopressin acetate is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively
价 格:¥电议型 号:T7284产 地:中国大陆