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T62590AChE-IN-25；化合物 AChE-IN-25AChE-IN-25
AChE-IN-25 is a selective, potent, non-competitive inhibitor of acetylcholinesterase (AChE) with an IC50 value of 2.95 μM. AChE-IN-25 can be used to study Alzheimer´s disease.
价 格：￥电议型 号：T62590产 地：中国大陆
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T6259Dizocilpine；地佐环平MK-801；地佐环平|||MK-801
MK-801 (Dizocilpine (MK-801)) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.
价 格：￥电议型 号：T6259产 地：中国大陆
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T62589TRPC5-IN-4；化合物 TRPC5-IN-4TRPC5-IN-4
TRPC5-IN-4, a potent and safe TRPC inhibitor, exhibits IC50 values of 14.07 nM and 65 nM for TRPC5 and TRPC4, respectively, indicating high efficacy. It does not cause damage to liver and kidney cellular components, making it suitable for chronic kidney disease (CKD) research [1].
价 格：￥电议型 号：T62589产 地：中国大陆
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T62588TCMDC-136230；化合物 TCMDC-136230TCMDC-136230
TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.
价 格：￥电议型 号：T62588产 地：中国大陆
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T62587TLR7 agonist 4；化合物 TLR7 agonist 4TLR7 agonist 4
TLR7 agonist 4 (Compound 1.2) is a TLR7 agonist (EC50: 4.3 nM).
价 格：￥电议型 号：T62587产 地：中国大陆
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T62586Cav 2.2/3.2 blocker 1；化合物 Cav 2.2/3.2 blocker 1Cav 2.2/3.2 blocker 1
Cav 2.2/3.2 blocker 1 (Compound 9e) is a neuronal calcium channel blocker that acts on Cav2.2 (IC50: 1.22 μM) and Cav3.2 (IC50: 80 μM). Can penetrate the central nervous system.
价 格：￥电议型 号：T62586产 地：中国大陆
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T62585NAS-181；化合物 NAS-181NAS-181
NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.
价 格：￥电议型 号：T62585产 地：中国大陆
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T62584CBR Agonist-2；化合物 CBR Agonist-2CBR Agonist-2
CBR Agonist-2 is a CB1 agonist (CB1R; CB1 ligand) (EC50: 960 nM, Ki: 970 nM). CBR Agonist-2 is a promising tool for the study of endogenous cannabinoid system-related diseases involving hCB1R.
价 格：￥电议型 号：T62584产 地：中国大陆
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T62583CBR Agonist-1；化合物 CBR Agonist-1CBR Agonist-1
CBR Agonist-1 (27a-cis) is a cannabinoid receptor (CBR) agonist that acts on CB1R (Ki: 0.18 μM) and CB2R (Ki: 1.22 μM). CBR Agonist-1 (27a-cis) can be used to study endogenous cannabinoid system-related diseases.
价 格：￥电议型 号：T62583产 地：中国大陆
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T62582WEHI-150；化合物 WEHI-150WEHI-150
WEHI-150 is an analog of mitoxantrone, a DNA interstrand cross-linker (t1/2=12.5 h). WEHI-150 is capable of forming covalent adducts on CpG sequences, with a particular preference for methylated CpG sites. Formaldehyde-activated WEHI-150 induces DNA interstrand cross-linking and blocks transcription in a concentration-dependent manner. WEHI-150 mediates the formation of covalent adducts that do not interact with guanine N-2 and forms adducts on new DNA sequences.
价 格：￥电议型 号：T62582产 地：中国大陆
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T62580PI3K-IN-37；化合物 PI3K-IN-37PI3K-IN-37
PI3K-IN-37 (Example 84.1) is an inhibitor of PI3K α (IC50: 6 nM), PI3K β (IC50: 8 nM) and PI3K δ (IC50: 4 nM). PI3K-IN-37 inhibits mTOR with an IC50 value of 4 nM.
价 格：￥电议型 号：T62580产 地：中国大陆
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T6258Zibotentan；化合物ZibotentanZD4054；ZD4054
Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.
价 格：￥电议型 号：T6258产 地：中国大陆
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T62579HBV-IN-19；化合物 HBV-IN-19HBV-IN-19
HBV-IN19 has inhibitory effects on hepatitis B virus (HBV) infection. HBV-IN19 inhibits HBsAg secretion and/or production and can be used in the study of HBV infection (e.g. chronic HBV infection).
价 格：￥电议型 号：T62579产 地：中国大陆
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T62578BuChE-IN-1；化合物 BuChE-IN-1BuChE-IN-1
BuChE-IN-1 (Compound 23) is a potent, highly blood-brain barrier-permeable, low cytotoxicity inhibitor of butyrylcholinesterase (BuChE). BuChE-IN-1 is a BuChE inhibitor that has the potential to be used in the study of AD.
价 格：￥电议型 号：T62578产 地：中国大陆
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T62577Anti-MRSA agent 5；化合物 Anti-MRSA agent 5Anti-MRSA agent 5
Anti-MRSA agent is a potent antagonist of MRSA (MIC50: 0.38 μg/mL) with low hERG activity (IC50: 40 μM). anti-MRSA agent also has low toxicity to mammalian cells and little potential to acquire bacterial resistance.
价 格：￥电议型 号：T62577产 地：中国大陆
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T62576Darglitazone Sodium；化合物 Darglitazone SodiumDarglitazone Sodium
Darglitazone Sodium is a thiazolidinedione, a selective, orally active PPAR-γ (peroxisome proliferator-activated receptor) agonist, which can be used in the study of type II diabetes as it effectively controls glucose and lipid metabolism.
价 格：￥电议型 号：T62576产 地：中国大陆
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T62575Anti-ToCV agent 1；化合物 Anti-ToCV agent 1Anti-ToCV agent 1
Anti-ToCV agent 1 can be used as a potential anti-ToCV drug.
价 格：￥电议型 号：T62575产 地：中国大陆
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T62574Antileishmanial agent-6；化合物 Antileishmanial agent-6Antileishmanial agent-6
Antileishmanial agent-6 is a potent anti-leishmanial agent with anti-leishmanial activity (IC50: 0.54 μM) and cytotoxicity (IC50: 10.2 μM) against Leishmania donovani and L-6.
价 格：￥电议型 号：T62574产 地：中国大陆
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T62573AMG-8718；化合物 AMG-8718AMG-8718
AMG-8718 is a selective, orally active and potent BACE1 inhibitor that acts on both BACE1 (IC50: 0.0007 μM) and BACE2 (IC50: 0.005 μM). AMG-8718 significantly reduces CSF and Aβ40 levels in the brain.
价 格：￥电议型 号：T62573产 地：中国大陆
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T62570THR-β agonist 1；化合物 THR-β agonist 1THR-β agonist 1
THRβ Agonist 1 is a potent and selective THRβ agonist. THRβ Agonist 1 has the potential to be used in studies of thyroid hormone receptor related disorders.
价 格：￥电议型 号：T62570产 地：中国大陆
