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T17262XE 991 dihydrochloride；化合物XE 991 dihydrochlorideXE 991 dihydrochloride
XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively).
价 格：￥电议型 号：T17262产 地：中国大陆
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T1725Y-27632 dihydrochloride；化合物Y-27632 dihydrochlorideY-27632 2HCl；反式-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐
Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.
价 格：￥电议型 号：T1725产 地：中国大陆
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T17068TH1834 dihydrochloride；化合物 T17068TH1834 dihydrochloride
TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor. TH1834 dihydrochloride causes apoptosis and enhances DNA damage in breast cancer.
价 格：￥电议型 号：T17068产 地：中国大陆
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T16855SB-772077B dihydrochloride；化合物 T16855SB-772077B dihydrochloride
SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).
价 格：￥电议型 号：T16855产 地：中国大陆
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T16524Philanthotoxin 74 dihydrochloride；化合物Philanthotoxin 74 盐酸盐PhTx-74 HCl|||PhTx 74 dihydrochloride；PhTx
Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.
价 格：￥电议型 号：T16524产 地：中国大陆
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T16443PCS1055 dihydrochloride；化合物 T16443PCS1055 dihydrochloride
PCS1055 dihydrochloride is an effective, selective, and competitive muscarinic M4 receptor antagonist (IC50: 18.1 nM and a Kd: 5.72 nM). PCS1055 dihydrochloride is also a potent AChE inhibitor (IC50 s: 22 nM and 120 nM for electric eel and human AChE, respectively). PCS1055 dihydrochloride inhibits radioligand [3H]-NMS binding to the M4 receptor (Ki: 6.5 nM). PCS1055 dihydrochloride shows >100-fold selectivity over M1-, M3-, and M5-receptors and 30-fold selectivity at the M2 receptor.
价 格：￥电议型 号：T16443产 地：中国大陆
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T15808Merestinib dihydrochloride化合物 T15808LY2801653 dihydrochloride
Merestinib dihydrochloride is an effective and orally bioavailable c-Met inhibitor (Ki=2 nM). It has anti-tumor activities and also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM).
价 格：￥电议型 号：T15808产 地：中国大陆
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T15746Lexibulin dihydrochloride；化合物 T15746CYT-997 dihydrochloride；CYT-997 dihydrochloride
Lexibulin 2Hcl is an effective tubulin polymerization inhibitor (IC50: 10-100 nM in cancer cell lines). It also has potent cytotoxic and vascular disrupting activity in vitro and in vivo.
价 格：￥电议型 号：T15746产 地：中国大陆
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T15674Tirbanibulin dihydrochloride化合物 T15674KX-01 (dihydrochloride)|||KX2-391 (dihydrochloride)
Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).
价 格：￥电议型 号：T15674产 地：中国大陆
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T15580Inolitazone dihydrochloride化合物 T15580RS5444 dihydrochloride|||CS-7017 dihydrochloride|||Efatutazone
Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth. Inolitazone dihydrochloride enhances the role of cell cycle kinase inhibitor p21 WAF1/CIP1.
价 格：￥电议型 号：T15580产 地：中国大陆
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T1542Pirenzepine dihydrochloride；盐酸哌仑西平Pirenzepine HCl|||Bisvanil|||Tabe|||LS519；Pirenzepine HCl|||Bisvan
Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist, inhibiting gastric secretion.
价 格：￥电议型 号：T1542产 地：中国大陆
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T15130Dilazep dihydrochloride；地拉卓二盐酸盐Dilazep dihydrochloride
Dilazep dihydrochloride is an adenosine uptake inhibitor. Dilazep dihydrochloride also inhibits the ischemic damage, membrane transport of nucleosides and platelet aggregation. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine.
价 格：￥电议型 号：T15130产 地：中国大陆
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T15112Dianicline dihydrochloride；化合物 T15112Dianicline dihydrochloride
Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.
价 格：￥电议型 号：T15112产 地：中国大陆
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T14998Copanlisib dihydrochloride；库潘尼西盐酸BAY 80-6946 dihydrochloride；库潘尼西盐酸|||BAY 80-6946 dihydrochloride
Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor (IC50s: 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ). Copanlisib dihydrochloride has superior antitumor activity and it also has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR.
价 格：￥电议型 号：T14998产 地：中国大陆
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T1476LPramipexole dihydrochloride；盐酸普拉克索Pramipexole dihydrochloride
Pramipexole dihydrochloride could be used to treat Parkinson disease.
价 格：￥电议型 号：T1476L产 地：中国大陆
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T14490Talipexole dihydrochloride；盐酸他利克索Domnin|||B-HT 920 dihydrochloride；Domnin|||盐酸他利克索|||B-HT 920 dihydr
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, respectively. It displays antiParkinsonian activity.
价 格：￥电议型 号：T14490产 地：中国大陆
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T14366AZ10606120 dihydrochloride；化合物AZ10606120 dihydrochlorideAZ10606120 dihydrochloride
AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors, respectively. AZ10606120 dihydrochloride inhibits tumor growth and has anti-angiogenic activity. AZ 10606120 acts as a negative allosteric modulator when bound to a site coupled to the ATP binding site.
价 格：￥电议型 号：T14366产 地：中国大陆
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T14362LAY 9944 dihydrochloride；化合物AY 9944 盐酸盐AY 9944 dihydrochloride
AY 9944 dihydrochloride is a intermediate.
价 格：￥电议型 号：T14362L产 地：中国大陆
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T14177Alexidine dihydrochloride；己联双辛胍二盐酸盐Alexidine dihydrochloride
Alexidine dihydrochloride has antifungal and antibiofilm activity against a diverse range of fungal pathogens. Alexidine dihydrochloride is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1, in mammalian cells and causes mitochondrial apoptosis. Thus, Alexidine dihydrochloride has the potential to be developed as a pan-antifungal, antibiofilm drug.
价 格：￥电议型 号：T14177产 地：中国大陆
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T13890SMARCA-BD ligand 1 for Protac dihydrochloride；化合物T13890SMARCA-BD ligand 1 for Protac dihydrochloride
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
价 格：￥电议型 号：T13890产 地：中国大陆
