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T16679BelzutifanMK-6482;PT2977
PT2977 is a potential treatment for clear cell renal cell carcinoma (ccRCC). PT2977 is an orally active and selective HIF-2α inhibitor (IC50: 9 nM). PT2977, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile.
价 格:¥电议型 号:T16679产 地:中国大陆
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T1667Tandutinib坦度替尼;NSC726292;CT53518;MLN518
Tandutinib (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR.
价 格:¥电议型 号:T1667产 地:中国大陆
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T16529BEBT-908PI3Kα inhibitor 1;MDK9521
BEBT-908 is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).
价 格:¥电议型 号:T16529产 地:中国大陆
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T16429GNE 2861
GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.
价 格:¥电议型 号:T16429产 地:中国大陆
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T1641Strontium ranelateDistrontium renelate;S12911;雷尼酸锶
Strontium ranelate, a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblast
价 格:¥电议型 号:T1641产 地:中国大陆
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T1636Paroxetine hydrochloride盐酸帕罗西汀;BRL29060A;FG-7051;BRL29060 hydrochloride;Paroxetine HCl
Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression.
价 格:¥电议型 号:T1636产 地:中国大陆
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T16329NitroflurbiprofenHCT 1206;NO-flurbiprofen;Nitroxybutyl flurbiprofen;硝基氟比洛芬
Nitroflurbiprofen is a cyclooxygenase inhibitor with nitric oxide (NO)-donating properties. It also modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats.
价 格:¥电议型 号:T16329产 地:中国大陆
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T16290NIK SMI1
NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM).
价 格:¥电议型 号:T16290产 地:中国大陆
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T1629Rifapentine利福喷丁;MDL473;Cyclopentylrifampicin;Rifapentina;Priftin;DL 473;Rifapentinum
Rifapentine is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.
价 格:¥电议型 号:T1629产 地:中国大陆
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T16162Mutated EGFR-IN-1Osimertinib analog;AZD9291中间体1
Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
价 格:¥电议型 号:T16162产 地:中国大陆
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T1615Irbesartan厄贝沙坦;SR-47436;BMS-186295
Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
价 格:¥电议型 号:T1615产 地:中国大陆
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T16129MPI_5a
MPI_5a is an effective and selective inhibitor of HDAC6 (IC50=36 nM). MPI_5a weakly inhibits other HDAC isoforms and it also inhibits acyl-tubulin accumulation in cells (IC50: 210 nM).
价 格:¥电议型 号:T16129产 地:中国大陆
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T15811LY2955303
LY2955303 is an effective and selective antagonist of retinoic acid receptor gamma (RARγ, Ki = 1.09 nM).
价 格:¥电议型 号:T15811产 地:中国大陆
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T15810LY2922470
LY2922470 is a potent, selective G protein-coupled receptor 40 (GPR40) agonist, with EC50s of 7 nM for human GPR40, 1 nM for mouse GPR40 and 3 nM for rat GPR40, respectively. LY2922470 reduces glucose levels along and increases insulin and GLP-1 significa
价 格:¥电议型 号:T15810产 地:中国大陆
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T15799LY2940094LY-2940094
LY-2940094 decreases ethanol self-administration in animal models. LY-2940094 is an effective, selective, and orally available nociceptin receptor antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM).
价 格:¥电议型 号:T15799产 地:中国大陆
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T15729LDN-91946
LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 μM).
价 格:¥电议型 号:T15729产 地:中国大陆
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T15629JTE-013
JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively).
价 格:¥电议型 号:T15629产 地:中国大陆
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T15562ImazamoxCL29926;(±)-Imazamox;甲氧咪草烟
Imazamox is a systemic herbicide with high selectivity, high activity, safety and broadspectrum activity. Imazamox inhibits the production of acetolactate synthase (ALS) in plants, which would then inhibit plant growth and ultimately lead to plant death.
价 格:¥电议型 号:T15562产 地:中国大陆
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T15529Hydroxy-PEG4-(CH2)2-Boc丙酸叔丁酯-四聚乙二醇
Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191).
价 格:¥电议型 号:T15529产 地:中国大陆