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  • T61340CAII-IN-3；化合物 CAII-IN-3CAII-IN-3

    CAII-IN-3 (compound 3h) is a thiosemicarbazone derivative known for its potent inhibition of carbonic anhydrase-II (CA-II). It exhibits an IC50 value of 13.4 μM [1].

    价 格：￥电议型 号：T61340产 地：中国大陆

  • T61248HDAC-IN-32；化合物 HDAC-IN-32HDAC-IN-32

    HDAC-IN-32 is a highly effective HDAC inhibitor presenting IC50 values of 5.2, 11, and 28 nM for HDAC1, HDAC2, and HDAC6, respectively. This compound demonstrates notable anti-proliferative properties against tumor cells, as well as significant in vivo antitumor efficacy, which can elicit antitumor immunity [1].

    价 格：￥电议型 号：T61248产 地：中国大陆

  • T61217RSV-IN-3；化合物 RSV-IN-3RSV-IN-3

    RSV-IN-3 (Compound 1) serves as a dual inhibitor targeting both the respiratory syncytial virus (RSV) and influenza virus A (IAV), demonstrating anti-RSV efficacy with an EC50 of 32.70 μM [1].

    价 格：￥电议型 号：T61217产 地：中国大陆

  • T61164hCAII-IN-3；化合物 hCAII-IN-3hCAII-IN-3

    hCAII-IN-3 (Compound 16) is an inhibitor of human carbonic anhydrase (hCA). It exhibits high affinity for hCA I, hCA II, hCA IX, and hCA XII, with Ki values of 403.8 nM, 5.1 nM, 10.2 nM, and 5.2 nM, respectively. Notably, hCA IX-IN-2 demonstrates anticancer activity [1].

    价 格：￥电议型 号：T61164产 地：中国大陆

  • T61161HIF-1α-IN-3；化合物 HIF-1α-IN-3HIF-1α-IN-3

    HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].

    价 格：￥电议型 号：T61161产 地：中国大陆

  • T61140IDO1/TDO-IN-3；化合物 IDO1/TDO-IN-3IDO1/TDO-IN-3

    IDO1/TDO-IN-3 is a powerful inhibitor targeting IDO1 and TDO enzymes. It displays noteworthy effectiveness against IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM). Additionally, IDO1/TDO-IN-3 demonstrates considerable in vivo anti-tumor properties while exhibiting no apparent toxicity [1].

    价 格：￥电议型 号：T61140产 地：中国大陆

  • T61139HDAC6-IN-3；化合物 HDAC6-IN-3HDAC6-IN-3

    HDAC6-IN-3 (Compound 14) is a potent anti-prostate cancer agent that acts as an orally active inhibitor of HDAC6. It has IC50 values ranging from 0.02-1.54 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10. Additionally, HDAC6-IN-3 also demonstrates effective inhibition of MAO-A (IC50 = 0.79 μM) and LSD1 [1].

    价 格：￥电议型 号：T61139产 地：中国大陆

  • T61084Tubulin polymerization-IN-37；化合物 Tubulin polymerization-IN-37Tubulin polymerization-IN-37

    Tubulin polymerization-IN-37 is a potent inhibitor (IC50: 2.3 μΜ) of tubulin polymerization by binding specifically to the colchicine site of tubulin and preventing colchicine binding. It has potential applications in cancer research, notably for lymphomas [1].

    价 格：￥电议型 号：T61084产 地：中国大陆

  • T61056Myt1-IN-3；化合物 Myt1-IN-3Myt1-IN-3

    Myt1-IN-3 is a potent inhibitor of Myt1 (IC50 <10 nM) [1].

    价 格：￥电议型 号：T61056产 地：中国大陆

  • T61002hMAO-B-IN-3；化合物 hMAO-B-IN-3hMAO-B-IN-3

    hMAO-B-IN-3 (Compound 15) is a potent hMAO-B inhibitor (IC 50 = 47.4 nM) with favourable drug-like properties and a broad safety window. Therefore, hMAO-B-IN-3 is a suitable candidate for lead optimization and multitarget-directed ligands development [1].

    价 格：￥电议型 号：T61002产 地：中国大陆

  • T60992COX-1/2-IN-3；化合物 COX-1/2-IN-3COX-1/2-IN-3

    COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].

    价 格：￥电议型 号：T60992产 地：中国大陆

  • T60902Tubulin polymerization-IN-31；化合物 Tubulin polymerization-IN-31Tubulin polymerization-IN-31

    Tubulin polymerization-IN-31 (Compound 4c) has antitumor activity and induces apoptosis of cancer cell. Tubulin polymerization-IN-31 is an inhibitor of tubulin polymerization with an IC 50 value of 3.64 μM [1].

    价 格：￥电议型 号：T60902产 地：中国大陆

  • T60895JAK-2/3-IN-3；化合物 JAK-2/3-IN-3JAK-2/3-IN-3

    JAK-2-/3-IN-3 (compound ST4j) can be used in lymph derived diseases and leukemia research. JAK-2-/3-IN-3 inhibits JAK2 autophosphorylation and induces apoptosis in a time- and dose-dependent manner. JAK-2-/3-IN-3 is a potent inhibitor of JAK2/3 with IC50 values of 13.00 and 14.86 nM for JAK2 and JAK3, respectively [1].

    价 格：￥电议型 号：T60895产 地：中国大陆

  • T60881NS2B/NS3-IN-3；化合物 NS2B/NS3-IN-3NS2B/NS3-IN-3

    NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .

    价 格：￥电议型 号：T60881产 地：中国大陆

  • T60866InhA-IN-3；InhA抑制剂3InhA-IN-3

    InhA-IN-3 (TU13) is a potent inhibitor of Mycobacterium tuberculosis InhA (enoyl ACP reductase) with potential anticancer and antiproliferative activities for the study of Mycobacterium tuberculosis infections.

    价 格：￥电议型 号：T60866产 地：中国大陆

  • T60863GPBAR1-IN-3；化合物 GPBAR1-IN-3GPBAR1-IN-3

    GPBAR1-IN-3 (Compound 14) is both a selective agonist for GPBAR1, with an EC50 value of 0.17 μM, and an antagonist for CysLT1R [1].

    价 格：￥电议型 号：T60863产 地：中国大陆

  • T60846ANO1-IN-3；化合物 ANO1-IN-3ANO1-IN-3

    ANO1-IN-3 (Compound 3n) can induces apoptosis that is a potent and selective inhibitor of ANO1 with an IC 50 of 1.23 μM [1].

    价 格：￥电议型 号：T60846产 地：中国大陆

  • T60831AChE/BChE-IN-3 hydrochloride；化合物 AChE/BChE-IN-3 hydrochlorideAChE/BChE-IN-3 hydrochloride

    AChE/BChE-IN-3 (BMC-1) hydrochloride is an AChE and BChE dual inhibitor. The IC50 values of AChE/BChE-IN-3 against equine serum BChE (eqBChE) and electric eel AChE (elAChE) is 0.383 μM and 6.08 μM, respectively [1].

    价 格：￥电议型 号：T60831产 地：中国大陆

  • T60829AAK1-IN-3；化合物 AAK1-IN-3AAK1-IN-3

    AAK1-IN-3 is a quinoline analogue that can be used in the research of neuropathic pain. AAK1-IN-3 is a brain-penetrant inhibitor of adaptor protein 2-associated kinase 1 (AAK1) (IC 50 = 11 nM) [1].

    价 格：￥电议型 号：T60829产 地：中国大陆

  • T60824Dyrk1A-IN-3；化合物 Dyrk1A-IN-3Dyrk1A-IN-3

    Dyrk1A-IN-3 (Compound 8b) is a highly selective inhibitor of dual-specificity tyrosine-regulated kinase 1A (DYRK1A). Dyrk1A-IN-3 has high binding affinity of DYRK1A with an IC 50 of 76 nM. Dyrk1A-IN-3 can be used in neurodegenerative disorders research, for example, Alzheimer’s Disease, Huntington’s Disease, and Parkinson’s Disease [1].

    价 格：￥电议型 号：T60824产 地：中国大陆

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