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T11303Fluorobexarotene;化合物FluorobexaroteneFluorobexarotene
Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.?Fluorobexarotene ?is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor.?Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.
价 格:¥电议型 号:T11303产 地:中国大陆
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T11302Flumexadol;化合物 T11302Flumexadol
Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A receptor. Flumexadol is an orally active non-narcotic analgesic.
价 格:¥电议型 号:T11302产 地:中国大陆
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T11301LFlomoxef sodium;氟氧头孢钠Flomoxef sodium
Flomoxef sodium, an antibiotic belonging to the oxacephem group, exhibits excellent activity against a broad spectrum of Gram-positive bacteria.
价 格:¥电议型 号:T11301L产 地:中国大陆
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T11301Flomoxef;氟氧头孢Flomoxef
Flomoxef is an antibiotic in oxacephem group and has excellent activity against various gram-positive bacteria.
价 格:¥电议型 号:T11301产 地:中国大陆
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T1130Gramicidin;短杆菌肽Gramicidinum|||Gramicidine|||Gramicidina;短杆菌肽|||Gramicidinum|||Gramicidine|||Gramicid
A group of peptide antibiotics from BACILLUS brevis. Gramicidin (Gramicidine) C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTHRICIN.
价 格:¥电议型 号:T1130产 地:中国大陆
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T11291FKBP12 PROTAC dTAG-13;化合物 T11291dTAG-13;dTAG-13
FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN. FKBP12 PROTAC dTAG-13 (dTAG-13) is a PROTAC-based heterobifunctional degrader.
价 格:¥电议型 号:T11291产 地:中国大陆
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T11278FG8119;化合物FG8119NNC13-8119;NNC13-8119
FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders.
价 格:¥电议型 号:T11278产 地:中国大陆
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T11220ER21355;化合物 T11220ER21355
ER21355, utilized for the treatment of prostatic diseases, acts as a phosphodiesterase 5 (PDE5) inhibitor.
价 格:¥电议型 号:T11220产 地:中国大陆
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T11213LEpertinib;化合物 T11213LS-22611;S-22611
Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM). It displays a strong antitumor activity.
价 格:¥电议型 号:T11213L产 地:中国大陆
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T11213Epertinib hydrochloride;化合物Epertinib hydrochlorideS-22611 hydrochloride;S-22611 hydrochloride
Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.
价 格:¥电议型 号:T11213产 地:中国大陆
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T11210EP1013;化合物 T11210F1013;F1013
EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.
价 格:¥电议型 号:T11210产 地:中国大陆
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T11204ENS-163 phosphate;化合物 T11204Sandoz ENS 163 phosphate|||ENS 213-163|||Thiopilocarpine phosphate;Sando
Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.
价 格:¥电议型 号:T11204产 地:中国大陆
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T1119Rasagiline;雷沙吉兰AGN1135|||TVP1012;雷沙吉兰|||AGN1135|||TVP1012
Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons disease.
价 格:¥电议型 号:T1119产 地:中国大陆
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T11154LEG01377 2HCl;EG01377二盐酸盐EG01377 2HCl(2227996-00-9 Free base);EG01377 2HCl(2227996-00-9 Free base)
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.
价 格:¥电议型 号:T11154L产 地:中国大陆
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T11154EG01377;化合物 T11154EG01377
EG01377 has antiangiogenic, antimigratory, and antitumor effects.EG01377 is a neuropilin-1 (NRP1) antagonist, with a Kd of 1.32 μM for NRP1-b1, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1, but shows no effect on NRP2.
价 格:¥电议型 号:T11154产 地:中国大陆
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T11140E6130;化合物 T11140E6130
E6130 may be effective in the treatment of inflammatory bowel disease and is a highly selective CX3CR1 regulator for oral administration.
价 格:¥电议型 号:T11140产 地:中国大陆
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T11139(E/Z)-BCI;化合物(E/Z)-BCINSC 150117;NSC 150117
(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signaling axis and inhibiting the NF-κB pathway.
价 格:¥电议型 号:T11139产 地:中国大陆
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T11138LLHF-535;化合物LHF-535LHF-535
LHF-535 is an antiviral compound. It has EC50s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively.
价 格:¥电议型 号:T11138L产 地:中国大陆
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T11138(E)-LHF-535;化合物 T11138(E)-LHF-535
(E)-LHF-535 is the E-isomer of LHF-535. LHF-535 is an antiviral agent with EC 50 s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively [1].
价 格:¥电议型 号:T11138产 地:中国大陆
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T11137(E)-GABAB receptor antagonist 1;(E)-GABAB受体拮抗剂-1(E)-GABAB receptor antagonist 1
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
价 格:¥电议型 号:T11137产 地:中国大陆