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T10946D4-abirateroneD4-abiraterone,Δ4-Abiraterone,CB-7627
D4-Abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid 5a-reductase (SRD5A), the main metabolite of abiraterone. D4-Abiraterone is also an antagonist of androgen receptor.
价 格:¥电议型 号:T10946产 地:美洲
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T11146EC359EC359
EC359Kd, 10.2 nM, interacts directly with LIFR and effectively blocks LIF/LIFR interaction. It is a potent, selective, highly affinity, and oral active leukemia inhibitor of LIFR.
价 格:¥电议型 号:T11146产 地:美洲
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T11178LELN 318463 racemateELN 318463 racemate
ELN 318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC50s of 12nM and 656 nM for PS1and PS2, respectively. ELN318463 is 51-fold more selective for PS1. ELN 318463 racemate is the racemate of ELN 318463. ELN 318
价 格:¥电议型 号:T11178L产 地:美洲
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T11216Eplivanserin mixtureEplivanserin mixture,SR-46349 (mixture),
Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist,?
价 格:¥电议型 号:T11216产 地:美洲
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T11227LEravacycline dihydrochlorideEravacycline dihydrochloride,TP-434 dihydrochloride,TP-434-046
Eravacycline dihydrochloride ?is a potent and broad-spectrum antibacterial agent.?
价 格:¥电议型 号:T11227L产 地:美洲
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T11246Etoricoxib D4Etoricoxib D4,MK-0663 D4,L-791456 D4
Etoricoxib D4 is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.Etoricoxib D4 ?is a deuterium labeled Etoricoxib.
价 格:¥电议型 号:T11246产 地:美洲
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T11267FASN-IN-1FASN-IN-1,TVB-2460,
FASN-IN-1 is a fatty acid synthase (FASN) inhibitor .
价 格:¥电议型 号:T11267产 地:美洲
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T11446GNF362GNF362
GNF362 also inhibits Itpka and Itpkc with IC50 values of 20 nM and 19 nM, respectively.?Inositol trisphosphate 3’ kinase B (Itpkb) is a Ca2+-dependent kinase, which phosphorylates the 3’ position of Ins (1,4,5) P3 to generate inositol 1,3,4,5-tetrakisphos
价 格:¥电议型 号:T11446产 地:美洲
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T11451GPI-1046GPI-1046
GPI-1046 is an analog of FK506, which is an immunophilin ligand that has been shown neuroprotective effects in neurodegenerative disease models. GPI-1046 readily crosses the blood-brain barrier and promotes the regeneration of dopamine (DA) cells in the C
价 格:¥电议型 号:T11451产 地:美洲
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T1146NifedipineNifedipine,BAY-a-1040,Procardia
Nifedipine is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and
价 格:¥电议型 号:T1146产 地:美洲
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T11461NE 52-QQ57NE 52-QQ57
NE 52-QQ57 has anti-inflammatory activity.?NE 52-QQ57 is a selective, and orally available GPR4 antagonist with an IC50 of 70 nM.?
价 格:¥电议型 号:T11461产 地:美洲
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T11462GPR84 antagonist 8GPR84 antagonist 8
GPR84 antagonist 8 is a selective GPR84 antagonist.
价 格:¥电议型 号:T11462产 地:美洲
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T11463GR 103691GR 103691
GR 103691 shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites.?GR 103691 is a potent, selective dopamine D3 receptor antagonist with a Ki value of 0.4 nM.?
价 格:¥电议型 号:T11463产 地:美洲
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T11464GRL0617GRL0617
GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM).
价 格:¥电议型 号:T11464产 地:美洲
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T11465GS-6207GS-6207
GS-6207 displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs). GS-6207 is a HIV-1 capsid inhibitor. GS-6207 shows anti-HIV activity with an EC50 of 100 pM in MT-4
价 格:¥电议型 号:T11465产 地:美洲
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T11468GSK-3 inhibitor 1GSK-3 inhibitor 1
GSK-3 inhibitor 1 is an inhibitor of GSK-3.
价 格:¥电议型 号:T11468产 地:美洲
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T11469GSK-3484862GSK-3484862
GSK-3484862 induces DNA hypomethylation to against cancer.?GSK-3484862 is a non-covalent inhibitor for Dnmt1.?
价 格:¥电议型 号:T11469产 地:美洲
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T11546hDHODH-IN-1hDHODH-IN-1
hDHODH-IN-1 has anti-inflammatory effect.?hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor.?
价 格:¥电议型 号:T11546产 地:美洲
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T1170Olopatadine hydrochlorideOlopatadine hydrochloride,KW4679,ALO4943A
Olopatadine hydrochloride is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.
价 格:¥电议型 号:T1170产 地:美洲
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T11846LHVSLHVS
LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion.?LHVS is a potent, non-selective cysteine protease inhibitor.?
价 格:¥电议型 号:T11846产 地:美洲