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T16479PF-04937319；化合物PF-04937319PF-04937319
PF-04937319 is an activator of glucokinase (EC50 =154.4 ?μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be used in research on the treatment of type 2 diabetes mellitus.
价 格：￥电议型 号：T16479产 地：中国大陆
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T16478PF-04447943化合物PF-04447943PF 04447943|||Edelinontrine|||PF04447943
PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits anti-inflammatory activity, attenuates inflammatory responses by inhibiting oxidative stress, inflammation, and modulating T-cell polarization, and may be useful for research on sickle cell anemia.
价 格：￥电议型 号：T16478产 地：中国大陆
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T16477PF-03715455；化合物 T16477PF-03715455
PF-03715455 potently inhibits LPS-induced TNFα production in human whole blood (IC50=1.7 nM). PF-03715455 is an effective inhibitor of inhaled p38 MAPK. PF-03715455 displays some selectivity for p38α over p38β (respective IC50: 0.88 and 23 nM). PF-03715455 has the potential for the treatment of COPD.
价 格：￥电议型 号：T16477产 地：中国大陆
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T16476PF-03654746；化合物PF-03654746PF-03654746
PF-03654746 is a selective antagonist of the histamine H3 receptor. PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimer´s disease. PF-03654746 can be used in studies about the treatment of allergic rhinitis.
价 格：￥电议型 号：T16476产 地：中国大陆
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T16471Perflubron；全氟溴辛烷Perfluorooctyl bromide|||PFOB；Perfluorooctyl bromide|||全氟溴辛烷|||PFOB
Perflubron (Perfluorooctyl bromide) can be emulsified with egg phospholipids (EYP) and displays exceptionally fast excretion characteristics. Perflubron(1-Bromoheptadecafluorooctane; Heptadecafluorooctyl bromide; Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography.
价 格：￥电议型 号：T16471产 地：中国大陆
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T16260N3-PEG4-C2-Pfp ester；化合物 T16260N3-PEG4-C2-Pfp ester
N3-PEG4-C2-Pfp ester is a four-unit polyethylene glycol linker, noncleavable in nature, specifically employed in the fabrication of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T16260产 地：中国大陆
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T16256N3-PEG3-C2-PFP ester；化合物 T16256N3-PEG3-C2-PFP ester
N3-PEG3-C2-PFP ester is a 3-unit polyethylene glycol (PEG) linker devoid of cleavable bonds. It is commonly employed in the synthesis of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T16256产 地：中国大陆
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T16254N3-PEG2-C2-PFP ester；化合物 T16254N3-PEG2-C2-PFP ester
The N3-PEG2-C2-PFP ester, a nonclaevable 2-unit polyethylene glycol (PEG) linker, is commonly employed in the synthesis of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T16254产 地：中国大陆
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T16158PF-02575799；化合物 T16158PF-02575799
PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).
价 格：￥电议型 号：T16158产 地：中国大陆
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T16090MK-0773；化合物 MK-0773PF-05314882；PF-05314882
MK-0773 (PF-05314882) is a selective androgen receptor modulator that binds to AR (IC50: 6.6 nM) for the study of diseases caused by endocrine abnormalities.
价 格：￥电议型 号：T16090产 地：中国大陆
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T16002Mal-PEG6-PFP ester；化合物 T16002Mal-PEG6-PFP ester
Mal-PEG6-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16002产 地：中国大陆
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T15998Mal-PEG5-PFP ester；化合物 T15998Mal-PEG5-PFP ester
Mal-PEG5-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T15998产 地：中国大陆
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T15993Mal-PEG4-PFP ester；化合物 T15993Mal-PEG4-PFP ester
Mal-PEG4-PFP ester is a non-cleavable antibody-drug conjugate (ADC) linker that incorporates a Maleimide moiety, a 4-unit Polyethylene Glycol (PEG) backbone, and a Pentafluorophenyl (PFP) ester.
价 格：￥电议型 号：T15993产 地：中国大陆
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T15988Mal-PEG3-PFP ester；化合物 T15988Mal-PEG3-PFP ester
Mal-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T15988产 地：中国大陆
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T15983Mal-PEG2-PFP ester；化合物 T15983Mal-PEG2-PFP ester
Mal-PEG2-PFP ester, an alkyl/ether-based PROTAC linker, facilitates the synthesis of PROTACs.
价 格：￥电议型 号：T15983产 地：中国大陆
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T15977Mal-PEG1-PFP ester；化合物 T15977Mal-PEG1-PFP ester
Mal-PEG1-PFP ester, an alkyl/ether-based PROTAC linker, is utilized in PROTAC synthesis.
价 格：￥电议型 号：T15977产 地：中国大陆
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T15654Ketohexokinase inhibitor 1；化合物Ketohexokinase inhibitor 1PF-06835919；PF-06835919
Ketohexokinase inhibitor 1 is a ketohexokinase inhibitor (IC50s: 8.4 nM and 66 nM for KHK-C and KHK-A, respectively).
价 格：￥电议型 号：T15654产 地：中国大陆
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T15526Hydroxy-PEG3-PFP ester；化合物 T15526Hydroxy-PEG3-PFP ester
Hydroxy-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T15526产 地：中国大陆
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T15517Hydroxy-PEG2-C2-PFP ester；化合物 T15517Hydroxy-PEG2-C2-PFP ester
Hydroxy-PEG2-C2-PFP ester, a PEG/Alkyl/ether-based PROteolysis TArgeting Chimeric (PROTAC) linker, is suitable for the synthesis of PROTACs.
价 格：￥电议型 号：T15517产 地：中国大陆
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T15340Fosdagrocorat；化合物 T15340PF-04171327；PF-04171327
Fosdagrocorat is an agonist of the dissociated glucocorticoid receptor.
价 格：￥电议型 号：T15340产 地：中国大陆
