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T11726JP1302 dihydrochloride;化合物JP1302 dihydrochlorideJP1302 dihydrochloride
JP1302 dihydrochloride is a selective, high affinity antagonist of the alpha2C-adrenoceptor (α2C-adrenoceptor), with a Ki (binding affinity) value of 28 nM and a Kb value (antagonist activity) of 16 nM.
价 格:¥电议型 号:T11726产 地:中国大陆
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T11721LJDTic dihydrochloride;化合物 T11721LJDTic dihydrochloride
JDTic is a powerful antagonist of kappa-opioid receptors (KOR), effectively inhibiting the antinociceptive effects induced by the κ-agonist U50, 488.
价 格:¥电议型 号:T11721L产 地:中国大陆
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T11693LIT1t dihydrochloride;化合物IT1t二盐酸盐IT1t dihydrochloride
IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4.
价 格:¥电议型 号:T11693L产 地:中国大陆
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T11522GYKI 52466 dihydrochloride;化合物 T11522GYKI 52466 dihydrochloride
GYKI 52466 dihydrochloride is orally active and non-competitive kainate- and AMPA-activated currents antagonist (IC50s: 7.5 μM and 11 μM). It is inactive against NMDA or γ-aminobutyric acid responses. It is a muscle relaxant and anticonvulsant agent and has good blood-brain barrier permeability.
价 格:¥电议型 号:T11522产 地:中国大陆
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T11500LGSK3368715 dihydrochlorideGSK3368715盐酸盐EPZ019997 dihydrochloride|||GSK3368715 2HCl|||EPZ019997 2HCl
GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active and potent inhibitor of type I protein arginine methyltransferases (PRMTs) with anticancer and antitumor activity, inhibiting PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, and can be used to study advanced solid tumors.
价 格:¥电议型 号:T11500L产 地:中国大陆
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T1147Chlorhexidine dihydrochloride;盐酸氯己定Chlorhexidine hydrochloride|||Chlorhexidine 2HCl|||NSC-185;盐酸氯己定|
Chlorhexidine dihydrochloride (NSC-185) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
价 格:¥电议型 号:T1147产 地:中国大陆
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T11345LLerociclib dihydrochloride;化合物Lerociclib dihydrochlorideG1T38 dihydrochloride;G1T38 dihydrochloride
Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/CyclinD1, respectively.
价 格:¥电议型 号:T11345L产 地:中国大陆
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T11227LEravacycline dihydrochloride;伊拉瓦环素盐酸盐TP-434-046|||TP-434 dihydrochloride;TP-434-046|||TP-434 dihydro
Eravacycline dihydrochloride (TP-434-046)?is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).
价 格:¥电议型 号:T11227L产 地:中国大陆
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T11173LElacestrant S enantiomer dihydrochloride;化合物 T11173LRAD1901 S enantiomer dihydrochloride|||RAD-1901
Elacestrant (RAD1901) dihydrochloride is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant S enantiomer dihydrochloride is an low activity enantiomer of elacestrant dihydrochloride.
价 格:¥电议型 号:T11173L产 地:中国大陆
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T1110Meclizine dihydrochloride盐酸美克洛嗪Meclozine dihydrochloride|||NSC28728|||Meclizine 2HCl|||盐酸美克洛嗪
Meclizine dihydrochloride (NSC28728) is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.
价 格:¥电议型 号:T1110产 地:中国大陆
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T11095DREADD agonist 21 dihydrochloride;化合物 T11095DREADD agonist 21 dihydrochloride (56296-18-5 free base)
DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].
价 格:¥电议型 号:T11095产 地:中国大陆
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T11011Dexpramipexole dihydrochloride;右旋普拉克索二盐酸盐KNS-760704 dihydrochloride|||R-(+)-Pramipexole dihydrochlor
Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist.
价 格:¥电议型 号:T11011产 地:中国大陆
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T10983LDDP-38003 dihydrochloride;DDP-38003盐酸盐DDP-38003 dihydrochloride
DDP-38003 dihydrochloride is an orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor (IC50: 84 nM).
价 格:¥电议型 号:T10983L产 地:中国大陆
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T10964LDB1976 dihydrochloride;DB1976盐酸盐DB1976 hydrochloride|||DB1976 2HCl;DB1976 hydrochloride|||DB1976 2HC
DB1976 dihydrochloride (DB1976 2HCl) , a transcription factor PU.1 inhibitor with potential anti-inflammatory activity, slowed down inflammation and fibrosis and improved glucose homeostasis and dyslipidemia in mice in in vivo experiments.DB1976 dihydrochloride promotes apoptosis and may be used in studies of metabolic dysfunction and non-alcoholic steatohepatitis.
价 格:¥电议型 号:T10964L产 地:中国大陆
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T10939D,L-Cystathionine dihydrochloride;化合物 T10939D,L-Cystathionine dihydrochloride
D,L-Cystathionine dihydrochloride is an intermediate in the synthesis of cysteine, which acts from the isotype of cysteine-β-synthase (CBS) produced by leucine and serine. Derived from cysteine. DL-cysteine contains a cysteine (βC-S) carbon-sulfur bond.
价 格:¥电议型 号:T10939产 地:中国大陆
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T10931d-Atabrine dihydrochloride;化合物 T10931d-Atabrine dihydrochloride
d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.
价 格:¥电议型 号:T10931产 地:中国大陆
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T10692CB-1158 dihydrochloride (2095732-06-0 free base);化合物 T10692INCB01158 dihydrochloride|||CB-1158 dihyd
CB-1158 dihydrochloride is an effective and orally active inhibitor of arginase (IC50s: 86 nM and 296 nM for recombinant human arginase 1 and 2).
价 格:¥电议型 号:T10692产 地:中国大陆
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T10639C-021 dihydrochloride;化合物C-021 dihydrochlorideC-021 dihydrochloride
C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.
价 格:¥电议型 号:T10639产 地:中国大陆
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T10568BMS-470539 dihydrochloride;化合物 T10568BMS-470539 dihydrochloride
BMS-470539 dihydrochloride is a highly potent and selective agonist of the melanocortin-1 receptor (MC-1R; IC50: 120 nM; EC50: 28 nM) with anti-inflammatory properties. It does not activate MC-3R and is a very weak partial agonist at MC-4R and MC-5R.
价 格:¥电议型 号:T10568产 地:中国大陆
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T10462LBavisant dihydrochloride hydrate;化合物 T10462LJNJ31001074AAC;JNJ31001074AAC
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1 mg/day, 3 mg/day and 10 mg/day groups, respectively; the change in the 10 mg/day group
价 格:¥电议型 号:T10462L产 地:中国大陆