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T76744Enokizumab;依诺凯组单抗MEDI-528;MEDI-528
Enokizumab?(MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.
价 格:¥电议型 号:T76744产 地:中国大陆
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T76743Emibetuzumab;依玛妥珠单抗LY2875358;LY2875358
Emibetuzumab is a potent humanized bivalent MET antibody (IgG4 type). Emibetuzumab has antitumor activity, inhibition of HGF-dependent and independent MET pathway activation and tumor growth, and can be used to study advanced castration-resistant prostate cancer.
价 格:¥电议型 号:T76743产 地:中国大陆
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T76742Emapalumab;依马利尤单抗NI-0501;NI-0501
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH).
价 格:¥电议型 号:T76742产 地:中国大陆
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T76741Eldelumab;埃迪鲁单抗BMS-936557|||MDX-1100;BMS-936557|||MDX-1100
Eldelumab (BMS-936557) is a humanized anti-IP-10 IgG type 1 monoclonal antibody with inhibitory activity against CXCL10.Eldelumab has anti-inflammatory activity and selectively binds to CXCL10 and can be used in the study of rheumatoid arthritis, ulcerative colitis, and Crohn´s disease.
价 格:¥电议型 号:T76741产 地:中国大陆
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T76740Carlumab;化合物 CarlumabCarlumab
Carlumab (CNTO 888), a humanized antibody with high affinity for CCL2 (chemokine ligand 2), is employed in cancer research, notably in the study of prostate cancer [1].
价 格:¥电议型 号:T76740产 地:中国大陆
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T76739Bococizumab;伯考赛珠单抗RN316|||PF-04950615;RN316|||PF-04950615
Bococizumab(PF-04950615) is a humanized mAb against PCSK9 and an inhibitor of the synthesis of PCSK9 in the liver that reduces the amount of low-density lipoprotein cholesterol (LDL-C) in the blood.Bococizumab is used to treat hypercholesterolemia.
价 格:¥电议型 号:T76739产 地:中国大陆
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T76738Bapineuzumab;化合物 BapineuzumabBapineuzumab
Bapineuzumab, an anti-β-amyloid protein (APP) monoclonal antibody, is utilized in Alzheimer’s disease (AD) research [1].
价 格:¥电议型 号:T76738产 地:中国大陆
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T76737Abrilumab;化合物 AbrilumabAbrilumab
Abrilumab, a fully human monoclonal antibody, targets the α4β7 integrin heterodimer, selectively binding to it. This specificity makes it a potential research tool for investigating inflammatory bowel disease (IBD) [1].
价 格:¥电议型 号:T76737产 地:中国大陆
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T76736Abituzumab;化合物 AbituzumabAbituzumab
Abituzumab (DI17E6), a humanized IgG2-type anti-integrin αV monoclonal antibody, notably decreases phosphorylation of FAK, Akt, and ERK. Its application is significant in cancer research, with a particular emphasis on prostate cancer [1].
价 格:¥电议型 号:T76736产 地:中国大陆
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T76735Mupadolimab;莫帕利单抗CPI-006;CPI-006
Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells.
价 格:¥电议型 号:T76735产 地:中国大陆
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T76733Enibarcimab;化合物 EnibarcimabEnibarcimab
Enibarcimab is a humanized murine monoclonal immunoglobulin G1 (IgG1) antibody, potentially applicable in the research of acute heart failure, COVID-19 infections, and septic shock [1].
价 格:¥电议型 号:T76733产 地:中国大陆
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T76731Gevokizumab;化合物 GevokizumabGevokizumab
Gevokizumab, a powerful anti-IL-1β antibody, inhibits IL-1β signaling allosterically, effectively reducing IL-1β´s binding affinity for its IL-1 receptor type I (IL-1RI) signaling receptor, while not affecting its interaction with the IL-1 counter-regulatory decoy receptor (IL-1 receptor type II) [1] [2].
价 格:¥电议型 号:T76731产 地:中国大陆
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T76730Uliledlimab;化合物 UliledlimabUliledlimab
Uliledlimab, a humanized monoclonal antibody, exhibits potent activity against CD73, inhibiting the conversion of extracellular adenosine monophosphate (AMP) to adenosine. It holds potential for use in cancer research [1].
价 格:¥电议型 号:T76730产 地:中国大陆
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T76729Lucatumumab;化合物 LucatumumabLucatumumab
Lucatumumab (HCD122), a fully human anti-CD40 antagonist monoclonal antibody, effectively inhibits CD40/CD40L-mediated signaling and promotes antibody-dependent cell-mediated cytotoxicity (ADCC) for tumor cell clearance. It is applicable in refractory lymphomas, CLL, and multiple myeloma research [1] [2].
价 格:¥电议型 号:T76729产 地:中国大陆
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T76728Vudalimab;化合物 VudalimabVudalimab
Vudalimab, a fully humanized bispecific monoclonal antibody, effectively inhibits both PD-1 and CTLA-4 immune checkpoint receptors. This dual action facilitates the selective activation of T-cells targeting tumors.
价 格:¥电议型 号:T76728产 地:中国大陆
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T76727Teprotumumab;替妥木单抗R 1507|||HZN 001;R 1507|||HZN 001
Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab reduces TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used in the study of thyroid-associated eye diseases.
价 格:¥电议型 号:T76727产 地:中国大陆
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T76726Zagotenemab;泽格特亲单抗LY33003560;LY33003560
Zagotenemab is a humanized antibody against the microtubule-associated protein tau that selectively regulates tau deposits in the brain. Zagotenemab can be used to study neurological disorders such as Alzheimer´s disease.
价 格:¥电议型 号:T76726产 地:中国大陆
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T76725Tilavonemab;化合物 TilavonemabTilavonemab
Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, targets amino acids 25-30 near the tau protein´s N-terminal end. It inhibits the uptake of tau aggregates by human and mouse neurons and diminishes brain atrophy, making it a potential tool in Alzheimer´s disease research [1].
价 格:¥电议型 号:T76725产 地:中国大陆
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T76724Nemolizumab;奈莫利珠单抗CIM331;CIM331
Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of interleukin-31 (IL-31) to its receptor. Nemolizumab can be used to study atopic dermatitis with pruritus.
价 格:¥电议型 号:T76724产 地:中国大陆
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T76723Tilvestamab;化合物 TilvestamabTilvestamab
Tilvestamab (BGB149), a humanized anti-AXL antibody, effectively blocks AXL-mediated cell signaling, significantly reduces Gas6-induced AXL activation, and inhibits downstream AKT phosphorylation in 786-0-Luc RCC cells. This compound is particularly useful in cancer research focusing on renal cell carcinomas with overexpressed AXL [1].
价 格:¥电议型 号:T76723产 地:中国大陆