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T12853SBI-477SBI-477
SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA. SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes.
价 格:¥电议型 号:T12853产 地:美洲
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T12877Seltorexant hydrochlorideSeltorexant hydrochloride,JNJ-42847922 hydrochloride,
Seltorexant hydrochloride is a selective, orally active and high-affinity antagonist of OX2R with pKi values of 8.0 and 8.1 for human and rat OX2R.
价 格:¥电议型 号:T12877产 地:美洲
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T12944SNT-207707SNT-207707
SNT-207707 is a potent, selective and orally active antagonist of melanocortin MC-4 receptor(IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor).
价 格:¥电议型 号:T12944产 地:美洲
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T12977SoraprazanSoraprazan,BYK61359,
Soraprazan is a reversible, and fast-acting gastric H+/K+ ATPase inhibitor.
价 格:¥电议型 号:T12977产 地:美洲
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T13017STL127705STL127705
STL127705 is a inhibitor of Ku 70/80 heterodimer protein(Ku70/80-DNA interaction, with an IC50 of 3.5 μM). STL127705 also inhibits Ku-dependent activation of DNA-PKCS kinase (IC50, 2.5 μM).
价 格:¥电议型 号:T13017产 地:美洲
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T13049SynucleozidSynucleozid,NSC 377363,
Synucleozid is a potent the SNCA?mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.
价 格:¥电议型 号:T13049产 地:美洲
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T13055T-3775440 hydrochlorideT-3775440 hydrochloride
T-3775440 hydrochloride is an irreversible inhibitor of lysine-specific histone demethylase (LSD1)(IC50 : 2.1 nM).
价 格:¥电议型 号:T13055产 地:美洲
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T13091TaspoglutideTaspoglutide,ITM077,R1583
Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetes
价 格:¥电议型 号:T13091产 地:美洲
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T13177Tocainide hydrochlorideTocainide hydrochloride
Tocainide hydrochloride is a blocker of sodium channel,and used for the treatment of tinnitus.
价 格:¥电议型 号:T13177产 地:美洲
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T13742LIvacaftor hydrateIvacaftor hydrate,VX-770 hydrate,
Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.
价 格:¥电议型 号:T13742L产 地:美洲
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T1377MethyldienedioneMethyldienedione,Dienedione,Trena
Methyldienedione is an anabolic steroid and a precursor to dienolone.
价 格:¥电议型 号:T1377产 地:美洲
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T13774ML390ML390
ML390 exerts its potent differentiation effect on multiple leukemia models.
价 格:¥电议型 号:T13774产 地:美洲
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T13776Mogroside II-?AMogroside II-?A
Mogroside II-?A is isolated from Siraitia grosvenorii.
价 格:¥电议型 号:T13776产 地:美洲
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T13777Moniliformin sodium saltMoniliformin sodium salt
Moniliformin sodium salt is water-soluble mycotoxin isolate from Fusarium moniliforme.
价 格:¥电议型 号:T13777产 地:美洲
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T14074A-770041A-770041
A-770041 is selective and orally active Src-family Lck inhibitor, and the other Src family kinase involved in T-cell signaling. A-770041 is a 147 nM inhibitor of Lck (1 mM ATP) and is 300-fold selective against Fyn, IC50 value: 147 nM Target: Lck.
价 格:¥电议型 号:T14074产 地:美洲
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T14076A 839977A 839977
A 839977 is a P2X7 selective antagonist and the antihyperalgesic effects of P2X7 receptor blockade are mediated by blocking the release of IL-1beta[1]. It blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values a
价 格:¥电议型 号:T14076产 地:美洲
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T14325ArterolaneArterolane,OZ 277,RBx 11160
Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.
价 格:¥电议型 号:T14325产 地:美洲
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T14377AZD5423AZD5423
AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM)[1] and it effectively reduces allergen-induced responses in subjects with mild allergic asthma[2].
价 格:¥电议型 号:T14377产 地:美洲
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T14577Biotin-DADOOBiotin-DADOO,Biotinyl-3,6-dioxaoctanediamine,EZ-Link Amine-PEO2-Biotin
Biotin-DADOO is a biotinylation reagent. Which can be used to synthesize a biotin-estradiol conjugate (i.e., biotin-DADOO-estradiol) to develop a direct, broad range enzyme immunoassay to measure plasma estradiol concentrations.
价 格:¥电议型 号:T14577产 地:美洲
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T14677BMS-690514BMS-690514
BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.
价 格:¥电议型 号:T14677产 地:美洲