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T17870cIAP1 ligand 1；cIAP1 配体1E3 ligase Ligand 12；E3 ligase Ligand 12
cIAP1 ligand 1 (E3 ligase Ligand 12) is an apoptotic protein ligand based on the LCL161 derivative that recruits IAP ubiquitin ligases to degrade target proteins, and can be used to couple with androgen receptor ligands for the development of protein degradation agents, which can be used in the study of prostate cancer.CAS ??13460-73-83-4
价 格：￥电议型 号：T17870产 地：中国大陆
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T17869cIAP1 ligand 2；化合物 T17869E3 ligase Ligand 11；E3 ligase Ligand 11
cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER.
价 格：￥电议型 号：T17869产 地：中国大陆
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T17868E3 ligase Ligand 10；化合物 T17868E3 ligase Ligand 10
E3 ligase Ligand 10 serves as a ligand for E3 ubiquitin ligase and can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. These PROTACs act as inducers of ubiquitination-mediated degradation, specifically targeting cancer-promoting proteins[1].
价 格：￥电议型 号：T17868产 地：中国大陆
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T17819Thalidomide-O-amido-C8-NH2；化合物 T17819E3 Ligase Ligand-Linker Conjugates 20|||Cereblon Ligand-Linker
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker. This compound is useful in the synthesis of PROTACs, as per reference [1].
价 格：￥电议型 号：T17819产 地：中国大陆
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T17818Thalidomide-O-amido-C4-NH2；化合物 T17818E3 Ligase Ligand-Linker Conjugates 19|||Cereblon Ligand-Linker
Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6) is a synthesized ligand-linker conjugate that combines a Thalidomide-based cereblon ligand with a linker. It functions as an E3 ligase ligand-linker conjugate and finds applications in the synthesis of PROTACs[1].
价 格：￥电议型 号：T17818产 地：中国大陆
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T17733ATRA-hydroxyimino；化合物 T17733CRABP-II ligand 1；CRABP-II ligand 1
ATRA-hydroxyimino, also known as CRABP-II ligand 1, is a chemical compound derived from Retinoic acid (ATRA). This compound binds to the cIAP1 ligand, specifically Bestatin, through a linker, resulting in the formation of a complex called SNIPER. The purpose of this complex is to degrade CRABP-II within IMR-32 cells[1].
价 格：￥电议型 号：T17733产 地：中国大陆
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T17731CL2A-SN-38；化合物CL2A-SN-38CL2A|||CL2A SN 38|||bystander effect|||SN-38|||antitumor|||CL2A-SN-38|||Inhi
CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a nonclaevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulf
价 格：￥电议型 号：T17731产 地：中国大陆
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T17727CCK2R Ligand-Linker Conjugates 1；化合物 T17727CCK2R Ligand-Linker Conjugates 1
CCK2R Ligand-Linker Conjugate 1 is a hydrophilic peptide linker that conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) as ligand-linker conjugates[1].
价 格：￥电议型 号：T17727产 地：中国大陆
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T17364AhR Ligand-Linker Conjugates 1；化合物 T17364E3 Ligase Ligand-Linker Conjugates 57；E3 Ligase Ligand-Link
AhR Ligand-Linker Conjugates 1, also known as E3 Ligase Ligand-Linker Conjugates 57, is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a SNIPER linker. It is specifically designed to be used in the development of SNIPER[1].
价 格：￥电议型 号：T17364产 地：中国大陆
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T17325Pomalidomide-PEG4-C-COOH；化合物Pomalidomide-PEG4-C-COOHCereblon Ligand -Linker Conjugates 1|||E3 Ligase
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
价 格：￥电议型 号：T17325产 地：中国大陆
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T1688Pregnanediol；孕二醇5Beta-Pregnane-3Alpha,20alpha-Diol|||Pregnandiol；5Beta-Pregnane-3Alpha,20alpha-Diol|
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol(5Beta-Pregnane-3Alpha,20alpha-Diol) has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.
价 格：￥电议型 号：T1688产 地：中国大陆
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T1667Tandutinib；坦度替尼MLN518|||CT53518|||NSC726292；MLN518|||CT53518|||NSC726292|||坦度替尼
Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR.
价 格：￥电议型 号：T1667产 地：中国大陆
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T1656LVandetanib Fumarate；化合物 T1656LHSDB 8198|||Zactima|||Caprelsa|||ZD 6474|||Vandetanib；HSDB 8198|||Zact
Vandetanib Fumarate is an orally available tyrosine kinase inhibitor. Vandetanib Fumarate works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epidermal growth factor receptor and to a lesser extent VEGFR-1, which are important targets in thyroid cancer (TC).
价 格：￥电议型 号：T1656L产 地：中国大陆
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T1656Vandetanib凡德他尼ZD6474|||凡德他尼
Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.
价 格：￥电议型 号：T1656产 地：中国大陆
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T1626Prostaglandin E1；前列地尔PGE1|||Alprostadil；前列地尔|||PGE1|||列腺素E1|||Alprostadil
Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3´
价 格：￥电议型 号：T1626产 地：中国大陆
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T16149Ms-PEG4-Ms；化合物 T161491,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane；1,11-Bis(methanesulfonyloxy)-3
Ms-PEG4-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T16149产 地：中国大陆
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T15238Epoprostenol sodium；化合物 T15238Prostaglandin I2 sodium salt|||Prostacyclin sodium salt|||Flolan；Prost
Epoprostenol sodium is a potent inhibitor of platelet aggregation used in pulmonary hypertension and transplantation.
价 格：￥电议型 号：T15238产 地：中国大陆
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T15191PROTAC ERRα ligand 1；化合物PROTAC ERRα ligand 1PROTAC ERRα ligand 1
PROTAC ERRα ligand 1 is an α (ERRα) antagonist of estrogen-related receptor (IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively).
价 格：￥电议型 号：T15191产 地：中国大陆
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T15190L(S,R,S)-AHPC-PEG4-NH2；化合物T15190LVHL Ligand-Linker Conjugates 4|||E3 ligase Ligand-Linker Conjugates
(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) is a synthetic E3 ligase ligand-linker conjugate comprising a VHL ligand based on (S,R,S)-AHPC and a 4-unit PEG linker.
价 格：￥电议型 号：T15190L产 地：中国大陆
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T15190(S,R,S)-AHPC-PEG4-NH2 hydrochloride；化合物 T15190E3 ligase Ligand-Linker Conjugates 7|||VH032-PEG4-NH2
(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology.
价 格：￥电议型 号：T15190产 地：中国大陆
