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T67956LLitoxetine HCl；利托西汀盐酸盐litoxetine HCL(86811-09-8 Free base)；litoxetine HCL(86811-09-8 Free base)
Litoxetine HCl is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor (SSRI) and mixed 5-hydroxytryptamine antagonist used in the treatment of urinary incontinence. Litoxetine HCl in the absence of antimuscarinic concentrations without antimuscarinic properties (10 nM-1 microM) caused concentration-dependent relaxation of isolated oesophageal muscle mucosa in rats, reducing carbachol tone by up to 37%. Higher concentrations of Litoxetine HCl (3 microM-300 microM) were associated with signi
价 格：￥电议型 号：T67956L产 地：中国大陆
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T67888LSamidorphan HCl；沙米多芬盐酸盐Samidorphan HCl（852626-89-2 free base）；Samidorphan HCl（852626-89-2 free base）
Samidorphan HCl is an orally active and highly potent modulator of the opioid system that binds to μ‐opioid, κ‐opioid, and delta-opioid receptors. Samidorphan HCl is a novel μ-opioid receptor antagonist, a partial agonist for k-opioid and delta-opioid receptors. Samidorphan HCl can be used to prevent and treat schizophrenia.
价 格：￥电议型 号：T67888L产 地：中国大陆
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T6782LBenzocaine xHCl(94-09-7(free base))；化合物Benzocaine xHClBenzocaine xHCl(94-09-7(free base))
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).
价 格：￥电议型 号：T6782L产 地：中国大陆
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T6772AZD3839 free base；化合物AZD3839AZD3839；AZD3839
AZD3839 free base is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.
价 格：￥电议型 号：T6772产 地：中国大陆
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T6764LATI-2341 acetate(1337878-62-2 free base)；化合物ATI-2341 acetateATI-2341 acetate(1337878-62-2 free base)
ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13. ATI-2341 acetate activates inhibitory heterotrimeric G protein (GI) to promote the inhibition of cAMP production and induce calcium mobilization.
价 格：￥电议型 号：T6764L产 地：中国大陆
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T6759LAP-III-a4 hydrochloride (1177827-73-4 free base)；化合物 T6759LENOblock hydrochloride|||AP-III-a4 hydroc
AP-III-a4 hydrochloride (ENOblock hydrochloride) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo. IC50 value: 0.576 uM [1] Target: enolase Enolase is a component of the glycolysis pathway and a "moonlighting" protein, with important roles in diverse cellular processes that are not related to its function in glycolysis. However, small molecule tools to pro
价 格：￥电议型 号：T6759L产 地：中国大陆
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T6553LJTC-801 free base；化合物 T6553LJTC-801；JTC-801
JTC-801 is a selective antagonist of the opioid receptor-like1 receptor (Ki: 8.2 nM).
价 格：￥电议型 号：T6553L产 地：中国大陆
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T64167LIfebemtinib FA；Ifebemtinib 甲酸盐BI-853520 FA（1227948-82-4 Free base)；BI-853520 FA（1227948-82-4 Free ba
Ifebemtinib FA (BI-853520 FA) is an orally active and potent inhibitor of adhesion patch kinase (FAK) with anticancer and antiproliferative activity for the study of ovarian and lung cancer.
价 格：￥电议型 号：T64167L产 地：中国大陆
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T64133LLaniquidar TFA；拉尼喹达三氟乙酸盐Laniquidar TFA(197509-46-9 Free base)|||R101933；Laniquidar TFA(197509-46-9 F
Laniquidar TFA (R101933) is a novel orally available non-competitive P-glycoprotein (P-gp) inhibitor with an IC50 value of 0.51 μM.Laniquidar has limited bioavailability and can be used to modulate the multidrug resistance transporter.Laniquidar can be used for the study of AML and myelodysplastic syndrome (MDS). Laniquidar is used to study acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).
价 格：￥电议型 号：T64133L产 地：中国大陆
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T6362Domatinostat；化合物4SC2024SC202|||4SC 202|||4SC-202 (free base)|||4SC-202；4SC202|||4SC 202|||4SC-202 (f
Domatinostat (4SC202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
价 格：￥电议型 号：T6362产 地：中国大陆
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T63399LmTOR/HDAC-IN-1 HCl；mTOR/HDAC抑制剂1盐酸盐mTOR/HDAC-IN-1 HCl（2815286-02-1 Free base)；mTOR/HDAC-IN-1 HCl（281
mTOR/HDAC-IN-1 HCl is a potent dual inhibitor of mTOR and HDAC with potential anti-inflammatory, anti-proliferative, autophagy and apoptosis-inducing effects for cancer research.
价 格：￥电议型 号：T63399L产 地：中国大陆
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T63351LMS8511 HCl；MS8511盐酸盐MS8511 HCl(2866408-21-9 Free base)；MS8511 HCl(2866408-21-9 Free base)
MS8511 HCl is a selective and potent covalent inhibitor of G9a/GLP that acts by targeting cysteine residues in the substrate binding site. MS8511 has anticancer activity and antiproliferative activity and reduces intracellular H3K9me2 levels.MS8511 can be used to study a wide range of cancers including brain, breast, and ovarian cancers .
价 格：￥电议型 号：T63351L产 地：中国大陆
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T63316BGC-20-1531 free base；化合物 BGC-20-1531 free baseBGC-20-1531 free base
BGC-20-1531 (PGN 1531) free base is a selective and potent prostaglandin EP4 receptor antagonist (pKB: 7.6) that exhibits potential for migraine research.
价 格：￥电议型 号：T63316产 地：中国大陆
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T6326BMS-345541；化合物BMS345541BMS-345541 free base|||IKK Inhibitor III|||BMS345541；BMS-345541 free base|||I
BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
价 格：￥电议型 号：T6326产 地：中国大陆
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T63208LAβ-IN-1 TFA；Aβ-IN-1 三氟乙酸盐Aβ-IN-1 TFA（2766509-32-2 Free base）；Aβ-IN-1 TFA（2766509-32-2 Free base）
Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.
价 格：￥电议型 号：T63208L产 地：中国大陆
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T6303LCCT128930 hydrochloride；化合物CCT128930 hydrochlorideCCT128930 hydrochloride(885499-61-6 Free base)；CCT
CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50: 168 nM) through the targeting of Met282 of AKT, as well as 20-fold selectivity over p70S6K (IC50: 120 nM).
价 格：￥电议型 号：T6303L产 地：中国大陆
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T62977MA242 free base；化合物 MA242 free baseMA242 free base
MA242 free base is a specific dual inhibitor of MDM2 and NFAT1 that induces apoptosis in pancreatic cancer cell lines. MA242 free base binds directly to MDM2 and NFAT1 with high affinity, induces MDM2 and NFAT1 protein degradation and inhibits NFAT1-mediated MDM2 transcription.
价 格：￥电议型 号：T62977产 地：中国大陆
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T6294NVP-BSK805 2HCl (1092499-93-8(free base))；化合物NVP-BSK805 2HClNVP-BSK805 dihydrochloride|||BSK 805|||N
NVP-BSK805 2HCl (1092499-93-8(free base)) (BSK 805)(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.
价 格：￥电议型 号：T6294产 地：中国大陆
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T62396LKB-5492 FA；KB-5492 甲酸盐KB-5492 FA（113594-64-2 Free base）；KB-5492 FA（113594-64-2 Free base）
KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS ??128-52-56-8
价 格：￥电议型 号：T62396L产 地：中国大陆
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T62396KB-5492 free base；化合物 KB-5492 free baseKB-5492 free base
KB-5492 free base is an orally available and selective antiulcer agent that inhibits sigma receptors, inhibits [3H]1,3-di(2-tolyl)guanidine (DTG) binding to sigma receptors, and may be useful in the study of gastric lesions and gastric secretion.
价 格：￥电议型 号：T62396产 地：中国大陆
