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T71371HOE-166 HCl；化合物 HOE-166 HClHOE-166 HCl
HOE-166 HCl is a novel calcium receptor antagonist.
价 格：￥电议型 号：T71371产 地：中国大陆
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T71370ICI-204879 HCl；化合物 ICI-204879 HClICI-204879 HCl
ICI-204879 HCl is a potent and selective agonists at the opioid kappa-receptor.
价 格：￥电议型 号：T71370产 地：中国大陆
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T71356Lanperisone HCl；化合物 Lanperisone HClLanperisone HCl
Lanperisone, also known as NK433, is a muscle relaxant. NK433 inhibited the facilitation of the flexor reflex mediated by group II afferent fibers that was induced by intrathecal administration of noradrenaline-HCl. NK433 had effects more than three times stronger and tending to be longer-lasting than those of eperisone-HCl. These results suggest that NK433 exerts a non-selective inhibition on spinal reflexes and that inhibition of the descending noradrenergic tonic facilitation within the spina
价 格：￥电议型 号：T71356产 地：中国大陆
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T71339XL413 HCl；XL413 盐酸盐XL413 hydrochloride|||BMS-863233 HCl；XL413 hydrochloride|||BMS-863233 HCl
XL413 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.XL413 HCl inhibited CK2 and PIM1 with IC50 values of 215 and 42 nM, respectively.XL413 HCl showed an EC50 value of 118 against pMCM.
价 格：￥电议型 号：T71339产 地：中国大陆
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T71338Patidegib HCl；化合物 Patidegib HClPatidegib HCl
Patidegip, laos known as Saridegib and IPI-926, is an orally bioavailable, cyclopamine-derived (for structure comparison see Fig 1) inhibitor of the Hedgehog (Hh) pathway with potential antineoplastic activity. Specifically, Hedgehog pathway inhibitor IPI-926 binds to and inhibits the cell membrane-spanning G-protein coupled receptor SMO, which may result in the suppression of Hh pathway signaling and a decrease in tumor cell proliferation and survival. SMO is activated upon binding of Hh ligan
价 格：￥电议型 号：T71338产 地：中国大陆
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T71333Iganidipine HCl；化合物 Iganidipine HClIganidipine HCl
NKY-722 (HCl), also known as Iganidipine, is a calcium channel blocker potentially for thetreatment of glaucoma.
价 格：￥电议型 号：T71333产 地：中国大陆
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T71302Norfluoxetine-d5 HCl；化合物 Norfluoxetine-d5 HClNorfluoxetine-d5 HCl
Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa
价 格：￥电议型 号：T71302产 地：中国大陆
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T71301Opaganib HCl；化合物 Opaganib HClOpaganib HCl
ABC294640, also known as Opaganib, is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. This may eventually lead to the induction of apoptosis a
价 格：￥电议型 号：T71301产 地：中国大陆
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T71298Ipenoxazone HCl；化合物 Ipenoxazone HClIpenoxazone HCl
Ipenoxazone HCl is a glutamate receptor antagonist potentially for the treatment of Alzheimer´s disease.
价 格：￥电议型 号：T71298产 地：中国大陆
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T71290EVT-101 HCl；化合物 EVT-101 HClEVT-101 HCl
EVT-101 is a GluN2B antagonist, binding at the same GluN1/GluN2B dimer interface as ifenprodil but adopting a remarkably different binding mode involving a distinct subcavity and receptor interactions.
价 格：￥电议型 号：T71290产 地：中国大陆
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T71266Omadacycline HCl；化合物 Omadacycline HClOmadacycline HCl
Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). The pri
价 格：￥电议型 号：T71266产 地：中国大陆
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T71254Clopidogrel HCl；化合物 Clopidogrel HClClopidogrel HCl
Clopidogrel HCl is the salt form of Clopidogrel (free base), an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex.
价 格：￥电议型 号：T71254产 地：中国大陆
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T71236Oxybutynin R-isomer HCl；化合物 Oxybutynin R-isomer HClOxybutynin R-isomer HCl
Oxybutynin R-isomer , also known as Aroxybutynin, is a muscarinic receptor antagonist. Aroxybutynin is the optically avtice inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. Oxybutynin exerts direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. It exhibits one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. No blo
价 格：￥电议型 号：T71236产 地：中国大陆
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T71227LGB-321 HCl；化合物 LGB-321 HClLGB-321 HCl
LGB-321 is a potent and selective ATP-competitive small molecule inhibitor of PIM kinases (Pan-PIM kinase inhibitor). LGB321 is unique relative to previously described PIM inhibitors, in that it is active in PIM2 dependent cell lines. , a kinase that has proven difficult to inhibit in the cellular context. Consistent with its activity on all three PIM kinases, LGB321 inhibits proliferation of a number of cell lines derived from diverse hematological malignancies, including MM, AML, CML and B-Cel
价 格：￥电议型 号：T71227产 地：中国大陆
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T71225Oxicodegol HCl；化合物 Oxicodegol HClOxicodegol HCl
Oxicodegol HCl is a mu?-opioid agonist used in the treatment of Moderate to Severe Chronic Low Back Pain
价 格：￥电议型 号：T71225产 地：中国大陆
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T71214MT-7716 HCl hydrate；化合物 MT-7716 HCl hydrateMT-7716 HCl hydrate
MT-7716 HCl hydrate is a NOP receptor agonist.
价 格：￥电议型 号：T71214产 地：中国大陆
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T71204Apatinib HC；化合物 Apatinib HCRivoceranib HCl|||YN-968D1 HCl；Rivoceranib HCl|||YN-968D1 HCl
Apatinib, also known as Rivoceranib and YN-968D1, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. The free-base form is also known as Rivoceranib. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SR
价 格：￥电议型 号：T71204产 地：中国大陆
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T71163Pimasertib HCl；化合物 Pimasertib HClPimasertib HCl
Pimasertib HCl is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity. Pimasertib selectively binds to and inhibits the activity of MEK1/2, preventing the activation of MEK1/2-dependent effector proteins and transcription factors, which may result in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation. MEK1/2 (MAP2K1/K2) are dual-specificity threonine/tyrosine kinases that play key roles in the activati
价 格：￥电议型 号：T71163产 地：中国大陆
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T71160Levomepromazine HCl；化合物 Levomepromazine HClLevomepromazine HCl
Levomepromazine HCl is a phenothiazine with pharmacological activity similar to that of both CHLORPROMAZINE and PROMETHAZINE. It has the histamine-antagonist properties of the antihistamines together with CENTRAL NERVOUS SYSTEM effects resembling those of chlorpromazine.
价 格：￥电议型 号：T71160产 地：中国大陆
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T71115Formoterol HCl；化合物 Formoterol HClFormoterol HCl
Formoterol HCl is a long-acting beta-2 adrenergic agonist (LABA).
价 格：￥电议型 号：T71115产 地：中国大陆
