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T76700Simtuzumab;辛妥珠单抗GS 6624|||AB 0024;GS 6624|||AB 0024
Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensatory cirrhosis caused by non-alcoholic steatohepatitis.
价 格:¥电议型 号:T76700产 地:中国大陆
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T76699Sabatolimab;Sabatolimab单抗MBG453|||NVP-MBG453;MBG453|||NVP-MBG453
Sabatolimab (MBG453), a humanized IgG4 (S228P) antibody targeting TIM-3, is a potent inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab has potential immunosuppressive activity and selectively binds to TIM-3 on immune cells and bone marrow cells.
价 格:¥电议型 号:T76699产 地:中国大陆
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T76698Rovalpituzumab;洛伐妥珠单抗Rovalpituzumab
Rovalpituzumab is a humanized monoclonal antibody targeting delta-like protein 3 (DLL3). Rovalpituzumab can be used to synthesize antibody-active molecule conjugates (ADCs). Rovalpituzumab has anticancer activity and is used to treat small cell lung cancer (SCLC).
价 格:¥电议型 号:T76698产 地:中国大陆
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T76697Panitumumab (anti-EGFR);化合物 Panitumumab (anti-EGFR)Panitumumab (anti-EGFR)
Panitumumab, a fully human IgG2 anti-EGFR monoclonal antibody, exerts anti-tumor effects by inhibiting tumor cell proliferation, survival, and angiogenesis. It is utilized in researching various cancers, including colon cancer [1] [2] [4].
价 格:¥电议型 号:T76697产 地:中国大陆
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T76696Onvatilimab;奥瓦利单抗JNJ-61610588;JNJ-61610588
Onvatilimab (JNJ-61610588) is a human IgG1 κ-anti-Vista (T-cell-activated V-domain Ig inhibitor) monoclonal antibody. Onvatilimab has antitumor activity and can be used to treat advanced head and neck cancers.
价 格:¥电议型 号:T76696产 地:中国大陆
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T76695Oleclumab;化合物 OleclumabOleclumab
Oleclumab (MEDI9447), a human IgG1λ monoclonal antibody, targets and inhibits CD73 functionality, demonstrating anti-tumor activity [1].
价 格:¥电议型 号:T76695产 地:中国大陆
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T76694Odronextamab;化合物 OdronextamabOdronextamab
Odronextamab, a fully human, hinge-stabilized IgG4-based bispecific antibody, targets CD3 receptors on T cells and CD20 receptors on B cells [1].
价 格:¥电议型 号:T76694产 地:中国大陆
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T76693Moxetumomab;化合物 MoxetumomabMoxetumomab
Moxetumomab, a recombinant immunotoxin targeting CD22, is utilized in the study of hairy cell leukemia (HCL) [1] [2].
价 格:¥电议型 号:T76693产 地:中国大陆
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T76692Mosunetuzumab;莫妥珠单抗BTCT-4465A;BTCT-4465A
Mosunetuzumab (BCT-4465A) is a humanized antibody based on immunoglobulin G1 that targets CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used to study relapsed or refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL) and refractory follicular lymphoma.
价 格:¥电议型 号:T76692产 地:中国大陆
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T76691Monalizumab;莫那利珠单抗Monalizumab
Monalizumab is a novel immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A). Monalizumab is a humanized monoclonal antibody against NKG2A that induces IFN-γ production, thereby activating natural killer cell function. Monalizumab has antitumor activity and can be used to study neck squamous cell carcinoma (HNSCC).
价 格:¥电议型 号:T76691产 地:中国大陆
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T76690Mavrilimumab;玛弗利木单抗CAM 3001;CAM 3001
Mavrilimumab (CAM 3001) is a monoclonal antibody with antiviral activity that has an affinity for the α subunit of the granulocytic-macrophage colony-stimulating factor (GM-CSF) receptor and blocks downstream intracellular signaling of GM-CSF. GM-CSF may be associated with an overactive inflammatory response associated with respiratory failure and death, and could be used to study rheumatoid arthritis.
价 格:¥电议型 号:T76690产 地:中国大陆
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T76689Margetuximab;化合物 MargetuximabMargetuximab
Margetuximab (MGAH22) is a chimeric anti-HER2 monoclonal antibody with an optimized Fc domain, exhibiting an EC50 value of 39.33 ng/mL. It is utilized in the research of metastatic HER2-positive breast cancer [1].
价 格:¥电议型 号:T76689产 地:中国大陆
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T76687Ibalizumab;艾巴利珠单抗TNX-355|||TMB-355;TNX-355|||TMB-355
Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4 receptor.Ibalizumab has anti-HIV-1 infectious activity and may be used to maintain normal immune function.
价 格:¥电议型 号:T76687产 地:中国大陆
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T76686Lebrikizumab;化合物 LebrikizumabLebrikizumab
Lebrikizumab, an IgG4 humanized monoclonal antibody, specifically targets and inhibits interleukin-13 (IL-13), thus impacting its function. This compound is utilized in asthma research [1].
价 格:¥电议型 号:T76686产 地:中国大陆
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T76685Glofitamab;格菲妥单抗RO7082859|||RG 6026|||CD20-TCB;RO7082859|||RG 6026|||CD20-TCB
Glofitamab (RO7082859) is a novel bivalent antibody directed against CD20-binding T cells.Glofitamab promotes T cell proliferation and activation and tumor cell killing by binding to CD20 on malignant cells.Glofitamab can be used for the palliation of relapsed or refractory B-cell lymphomas.
价 格:¥电议型 号:T76685产 地:中国大陆
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T76684Girentuximab;吉妥昔单抗cG250|||WX-G250|||G250;cG250|||WX-G250|||G250
Girentuximab (G250) is a potent anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anticancer activity for the study of uroepithelial carcinoma PET (ZiPUP).
价 格:¥电议型 号:T76684产 地:中国大陆
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T76683Gantenerumab;化合物 GantenerumabGantenerumab
Gantenerumab, a fully human IgG1 monoclonal antibody targeting amyloid-β (Aβ), exhibits sustained binding to cerebral Aβ. It is employed in research focused on Alzheimer´s disease [1].
价 格:¥电议型 号:T76683产 地:中国大陆
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T76682Galcanezumab;加那珠单抗LY 2951742;LY 2951742
Galcanezumab is a humanized IgG4 monoclonal antibody targeting the CGRP ligand, which binds to the ligand calcitonin gene-related peptide. Galcanezumab can be used to prevent and treat migraines or cluster headaches.
价 格:¥电议型 号:T76682产 地:中国大陆
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T76681Fresolimumab;非苏木单抗GC1008;GC1008
Fresolimumab (GC1008) is a specific human anti-transforming growth factor β monoclonal antibody that binds to the active forms of human TGFβ1, TGFβ2, and TGFβ3 and can be used to study focal segmental glomerulosclerosis and cancer in adults.
价 格:¥电议型 号:T76681产 地:中国大陆
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T76680Fremanezumab;化合物 FremanezumabFremanezumab
Fremanezumab (TEV-48125), a humanized IgG2a monoclonal antibody, potently and selectively targets the calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide implicated in the central and peripheral mechanisms of migraine. It holds promise for research into chronic migraine treatment [1].
价 格:¥电议型 号:T76680产 地:中国大陆