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T36994MRT 67307 dihydrochlorideMRT 67307 dihydrochloride
MRT 67307 dihydrochloride is a dual inhibitor of the IKKε and TBK-1 with IC50s of 160 and 19 nM, respectively. MRT67307 dihydrochloride also inhibits ULK1 and ULK2 with IC50s of 45 and 38 nM, respectively. MRT67307 dihydrochloride also blocks autophagy in cells.
价 格:¥电议型 号:T36994产 地:中国大陆
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T24076FzM1
FzM1 is a negative allosteric modulator (NAM) of Frizzled receptor FZD4. FzM1 reduces WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=?6.2). FzM1 binds to an allosteric binding site located in intracellular loop 3 (ICL3) of FZD4 and alters the conformation of the receptor, ultimately inhibiting the WNT/β-catenin cascade
价 格:¥电议型 号:T24076产 地:中国大陆
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T7637Deltorphin IInhibitor,Deltorphin-1,inhibit,Deltorphin I,Deltorphin1,Opioid Receptor
Deltorphin I(TFA) is an agonist of δ-opioid receptor.
价 格:¥电议型 号:T7637产 地:中国大陆
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T7964Isomaltoral,food,stabilizing,Inhibitor,Lactate Dehydrogenase,inhibit,agent,LDH,Isomalt,industry,exci
Palatinitol is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranoside
价 格:¥电议型 号:T7964产 地:中国大陆
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T9963MPT0B390colorectal cancer,HDAC,Inhibitor,inhibit,HDAC inhibitory ability,MPT0B390,colon cancer,Histo
MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.
价 格:¥电议型 号:T9963产 地:中国大陆
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T23285S 14506 hydrochlorideS 14506 hydrochloride
S 14506 hydrochloride is a 5-HT1A receptor full agonist.
价 格:¥电议型 号:T23285产 地:中国大陆
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T15608Jarin-1Jarin 1,Jarin1
Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM). Jarin-1 specific suppresses bioactive JA biosynthesis in Arabidopsis and other plants.
价 格:¥电议型 号:T15608产 地:中国大陆
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T7197Fadrozole(Rac)-FAD286,inhibit,Fadrozole,CGS 16949A,Inhibitor,Aromatase
Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)
价 格:¥电议型 号:T7197产 地:中国大陆
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TP1761LHandle region peptide, rat acetateHandle region peptide, rat acetate
Handle region peptide, rat acetate is a prorenin receptor antagonist, suppresses the progression of diabetic nephropathy and has anti-inflammatory in the eye.
价 格:¥电议型 号:TP1761L产 地:中国大陆
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T677434-Pyridinecarboxaldehyde, 2-(2-pyridinyl)hydrazone, [C(E)]-4Pyridinecarboxaldehyde,2(2pyridinyl)hydr
4-Pyridinecarboxaldehyde, 2-(2-pyridinyl)hydrazone, [C(E)]- is a ligand of mixed-ligand coordination polymer [Zn4(bdc)4(ppmh)2(H2O)]n.
价 格:¥电议型 号:T67743产 地:中国大陆
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T14946Ch55
Ch55 is an effective inducer of the differentiation of HL60 cells (EC50 = 200 nM) and shows high affinity with RAR-α and RAR-β receptors. Ch55 can be used in studies about cancer.
价 格:¥电议型 号:T14946产 地:中国大陆
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T6446ClevudineOrthopoxvirus,half-life,nucleoside,DNA/RNA Synthesis,analog,Inhibitor,polymerase,Hepatitis
Clevudine is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DN
价 格:¥电议型 号:T6446产 地:中国大陆
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T35336Furosemide sodium
Furosemide sodium is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema.
价 格:¥电议型 号:T35336产 地:中国大陆
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T16873SERCA2a activator 1Ca channels,phospholamban,Inhibitor,Ca2+ channels,SERCA2a activator 1,SERCA2a,SER
SERCA2a activator 1 is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a activator. SERCA2a activator 1 decreases phospholamban inhibition and enhances the systolic and diastolic functions of the heart.
价 格:¥电议型 号:T16873产 地:中国大陆
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T86486-AZATHYMINE6-Azathymine,6AZATHYMINE,antibacterial,nucleobase,Inhibitor,Influenza Virus,DNA,6-nitrog
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic acid with a Ki of approximately 8.9 mM.
价 格:¥电议型 号:T8648产 地:中国大陆
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T7152Ravuconazoleinhibit,ER30346,BMS207147,Ravuconazole,BMS 207147,Fungal,ER 30346,Inhibitor
Ravuconazole is a potent triazole antifungal that potently inhibits a wide range of fungi.
价 格:¥电议型 号:T7152产 地:中国大陆
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T6836FIIN-2inhibit,FGFR,FIIN2,FIIN 2,Fibroblast growth factor receptor,Inhibitor,FIIN-2
FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.
价 格:¥电议型 号:T6836产 地:中国大陆
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T13368YLF-466D
YLF-466D is a newly developed AMPK activator, which inhibits platelet aggregation.
价 格:¥电议型 号:T13368产 地:中国大陆
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T21967MEG hemisulfate
MEG hemisulfate is a potent and selective inhibitor of the inducible NO synthase (iNOS), with EC50s of 11.5, 110, and 60 μM for iNOS, ecNOS, and bNOS respectively in tissue homogenates. MEG hemisulfate is also a potent scavenger of peroxynitrite and inhibits peroxynitrite-induced oxidative processes. MEG hemisulfate has a protective effect in many experimental models of inflammation, including ischemia/reperfusion injury, periodontitis, hemorrhagic shock, inflammatory bowel disease, and endotoxi
价 格:¥电议型 号:T21967产 地:中国大陆
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TQ0082AticaprantCERC 501,inhibit,LY2456302,Opioid Receptor,Aticaprant,Inhibitor,CERC501,LY 2456302
Aticaprant (CERC-501) is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM).
价 格:¥电议型 号:TQ0082产 地:中国大陆