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  • T69297Leupeptin HCl；化合物 Leupeptin HClLeupeptin HCl

    Leupeptin is a naturally occurring protease inhibitor that can inhibit cysteine, serine and threonine peptidases. Leupeptin is an organic compound produced by actinomycetes. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), porcine kallikrein), and cysteine proteinases (papain, cathepsin B (Ki = 4.1 nM), endoproteinase Lys-C). It does not inhibit α-chymotrypsin or thrombin. Leupeptin is a competitive transition state inhibitor and its inhibition may be relieved by

    价 格：￥电议型 号：T69297产 地：中国大陆

  • T69283Amikhellin HCl；化合物 Amikhellin HClAmikhellin HCl

    Amikhellin HCl, an antimitotic drug, is a synthetic water-soluble derivative of khellin, an alkaloid extracted from seeds of Ammi Visnaga. Amikhellin has been used so far mostly as a vasodiator. Amikhellin binds to double-stranded DNA by an intercalation process. It inhibits the DNA-polymerase from murine sarcoma leukemia virus.

    价 格：￥电议型 号：T69283产 地：中国大陆

  • T69263HA-966 HCl；化合物 HA-966 HClHA-966 HCl

    HA-966 HCl is an NMDA receptor complex glycine site antagonist.

    价 格：￥电议型 号：T69263产 地：中国大陆

  • T69234Piperilate HCl；化合物 Piperilate HClPiperilate HCl

    Piperilate HCl is an antispasmodic, antimuscarinic agent. It is a muscarinic cholinergic receptor antagonist.

    价 格：￥电议型 号：T69234产 地：中国大陆

  • T6922ORY1001；化合物ORY1001RG-6016|||ORY-1001 (RG-6016) 2HCl|||ORY-1001|||ORY 1001；RG-6016|||ORY-1001 (RG-601

    ORY1001 (ORY 1001) is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor, with high selectivity against related FAD dependent aminoxidases with IC50 of <20 nM.

    价 格：￥电议型 号：T6922产 地：中国大陆

  • T69218PUMAi HCl；化合物 PUMAi HClPUMAi HCl

    PUMAi is an inhibitor of p53 up-regulated modulator of apoptosis (PUMA), a BH3-only Bcl-2 family member, mitigating acetaminophen (APAP)-induced hepatocyte necrosis and liver injury.

    价 格：￥电议型 号：T69218产 地：中国大陆

  • T69197AG-012986 HCl；化合物 AG-012986 HClAG-012986 HCl

    AG-012986 HCl is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 HCl showed antiproliferative activities in vitro with IC(50)s of <100 nmol/L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 HCl was seen (tumor growth inhibition, >83.1%) in 10 of 11 human xenograft tumor models. AG-012986 HCl also showed dose-dependent retinoblas

    价 格：￥电议型 号：T69197产 地：中国大陆

  • T69170ATC0065 HCl；化合物 ATC0065 HClATC0065 HCl

    ATC0065 dihydrochloride is a novel nonpeptidic and potent melanin-concentrating hormone receptor 1 (MCHR1) selective antagonist.

    价 格：￥电议型 号：T69170产 地：中国大陆

  • T69148Colterol HCl；化合物 Colterol HClColterol HCl

    Colterol HCl is the salt form of Colterol (free base), a short-acting β2-adrenoreceptor agonist. Bitolterol, a prodrug for colterol, is used in the management of bronchospasm in asthma and chronic obstructive pulmonary disease.

    价 格：￥电议型 号：T69148产 地：中国大陆

  • T69144Hexylcaine HCl；化合物 Hexylcaine HClHexylcaine HCl

    Hexylcaine HCl also called cyclaine or osmocaine, is a short-acting local anesthetic. It acts by inhibiting sodium channel conduction. Overdose can lead to headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function.

    价 格：￥电议型 号：T69144产 地：中国大陆

  • T69133Etozolin HCl；化合物 Etozolin HClEtozolin HCl

    Etozolin HCl is a safe and effective diuretic agent in the treatment of acute cardiac failure. In isolated rings of guinea-pig aorta not responding to acetylcholine, the diuretic dexetozoline did not influence basal vascular tone but inhibited noradrenaline- and histamine-induced contractions. Dexetozoline has a very high bioavailability after oral administration and is fairly lipohilic. The half-life of etozolin is 2.5 h. Dexetozoline accumulates in cirrhosis.

    价 格：￥电议型 号：T69133产 地：中国大陆

  • T69129Clozapine HCl；化合物 Clozapine HClClozapine HCl

    Clozapine HCl is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a

    价 格：￥电议型 号：T69129产 地：中国大陆

  • T69119Disopyramide HCl；化合物 Disopyramide HClDisopyramide HCl

    Disopyramide HCl is the salt form of Disopyramide, an antiarrhythmic medication used in the treatment of ventricular tachycardia. It is a sodium channel blocker and therefore classified as a Class 1a anti-arrhythmic agent. Disopyramide has a negative inotropic effect on the ventricular myocardium, significantly decreasing the contractility. Disopyramide also has an anticholinergic effect on the heart which accounts for many adverse side effects. Disopyramide is available in both oral and intrave

    价 格：￥电议型 号：T69119产 地：中国大陆

  • T69075Dicentrine HCl；化合物 Dicentrine HClDicentrine HCl

    Dicentrine HCl is the salt form of Dicentrine, an alpha 1-adrenoceptor antagonist effective against human hyperplastic prostates.

    价 格：￥电议型 号：T69075产 地：中国大陆

  • T69021Nifedipine HCl；化合物 Nifedipine HClNifedipine HCl

    Nifedipine HCl is a potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

    价 格：￥电议型 号：T69021产 地：中国大陆

  • T69020Ethomoxane HCl；化合物 Ethomoxane HClEthomoxane HCl

    Ethomoxane HCl is the salt form of Ethomoxane, an antagonist of alpha-adrenoreceptor exerting antihypertensive properties.

    价 格：￥电议型 号：T69020产 地：中国大陆

  • T68992Pempidine HCl；化合物 Pempidine HClPempidine HCl

    Pempidine HCl is a nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has largely been supplanted for that purpose by more specific drugs.

    价 格：￥电议型 号：T68992产 地：中国大陆

  • T6899MRT68921；化合物MRT68921MRT68921 HCl；MRT68921 HCl

    MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.

    价 格：￥电议型 号：T6899产 地：中国大陆

  • T68966Oxmetidine HCl；化合物 Oxmetidine HClOxmetidine HCl

    Oxmetidine HCl is an antagonist to Histamine H2 Receptors

    价 格：￥电议型 号：T68966产 地：中国大陆

  • T68948Detorubicin HCl；化合物 Detorubicin HClDetorubicin HCl

    Detorubicin is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin.

    价 格：￥电议型 号：T68948产 地：中国大陆

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