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T14421Azido-PEG2-CH2COOH；化合物 T14421Azido-PEG2-CH2COOH
Azido-PEG2-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14421产 地：中国大陆
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T14411Azido-PEG1-PFP ester；化合物 T14411Azido-PEG1-PFP ester
Azido-PEG1-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14411产 地：中国大陆
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T14401Azido-C2-SS-PEG2-C2-acid；化合物 T14401Azido-C2-SS-PEG2-C2-acid
Azido-C2-SS-PEG2-C2-acid is a two-unit cleavable PEG linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].
价 格：￥电议型 号：T14401产 地：中国大陆
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T14323ARQ 531；化合物ARQ 531ARQ 531
ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic activity, with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively.
价 格：￥电议型 号：T14323产 地：中国大陆
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T14321ARN19874；化合物 T14321ARN19874
ARN19874 is a selective, reversible uncompetitive N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity inhibitor. With an IC50 of ~34 μM[1].
价 格：￥电议型 号：T14321产 地：中国大陆
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T14315AR-9281；化合物AR-9281APAU；APAU
AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes
价 格：￥电议型 号：T14315产 地：中国大陆
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T14311APN-?NH2；化合物 T14311APN-?NH2
APN- NH2 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
价 格：￥电议型 号：T14311产 地：中国大陆
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T14283amyloid P-IN-1；化合物amyloid P-IN-1amyloid P IN 1|||amyloid P-IN-1|||amyloid PIN1；amyloid P IN 1|||amyl
amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer´s disease, amyloidosis, osteoarthritis, and type 2 diabetes mellitus.
价 格：￥电议型 号：T14283产 地：中国大陆
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T14261Aminooxy-PEG2-alcohol；化合物 T14261Aminooxy-PEG2-alcohol
Aminooxy-PEG2-alcohol is a non-cleavable PEG linker consisting of two units, utilized in the synthesis of antibody-drug conjugates (ADCs) [1]. This compound serves as a PEG-based PROTAC linker for the synthesis of PROTACs as well [2].
价 格：￥电议型 号：T14261产 地：中国大陆
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T14251Amino-PEG8-Boc；化合物 T14251Amino-PEG8-Boc
Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T14251产 地：中国大陆
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T14241Amino-PEG4-CH2COOH；化合物 T14241Amino-PEG4-CH2COOH
Amino-PEG4-CH2COOH is a PEG-based PROTAC linker and a non-cleavable 4 unit PEG ADC linker employed in the synthesis of PROTACs and antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T14241产 地：中国大陆
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T14231Amino-PEG2-NH-Boc；化合物 T14231Amino-PEG2-NH-Boc
Amino-PEG2-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14231产 地：中国大陆
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T14221Amino-ethyl-SS-PEG3-NHBoc；化合物 T14221Amino-ethyl-SS-PEG3-NHBoc
Amino-ethyl-SS-PEG3-NHBoc is a cleavable 3-unit PEG ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T14221产 地：中国大陆
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T14214AMG 511；化合物AMG 511AMG 511
AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks(Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kα, β, δ and γ, respectively). It exhibits anti-tumor activity in mouse glioblastoma xenograft model[1]. AMG 511 significantly suppresses PI3K signaling that is indicated by p-Akt (Ser473) decrease.
价 格：￥电议型 号：T14214产 地：中国大陆
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T14211AMG-009；化合物 T14211AMG009|||AMG 009|||AMG009|||AMG-009|||AMG 009；AMG009|||AMG 009|||AMG009|||AMG-009|
AMG-009 is a prostaglandin D2 antagonist. For CRTH2 and DP receptors, the IC50s are 3 nM and 12 nM, respectively.
价 格：￥电议型 号：T14211产 地：中国大陆
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T14201AM-2099；化合物 T14201AM-2099
AM-2099 is a voltage-gated sodium channel Nav1.7 inhibitor (IC50: 0.16 μM).
价 格：￥电议型 号：T14201产 地：中国大陆
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T14175Aldose reductase-IN-1；化合物Aldose reductase-IN-1AT-001|||Caficrestat；AT-001|||Caficrestat
Aldose reductase-IN-1 (AT-001) is a aldose reductase inhibitor (IC50: 28.9 pM).
价 格：￥电议型 号：T14175产 地：中国大陆
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T14171Ald-Ph-amido-PEG2-C2-acid；化合物 T14171Ald-Ph-amido-PEG2-C2-acid
Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].
价 格：￥电议型 号：T14171产 地：中国大陆
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T14161Ald-PEG1-C2-Boc；化合物 T14161Ald-PEG1-C2-Boc
Ald-PEG1-C2-Boc is an alkyl-ether-based linker utilized for the synthesis of PROTACs, a class of small molecules that induce targeted protein degradation[1].
价 格：￥电议型 号：T14161产 地：中国大陆
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T14151AKR1C1-IN-1；化合物AKR1C1-IN-1AKR1C1-IN-1
AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1).
价 格：￥电议型 号：T14151产 地：中国大陆
