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T80061Hongotoxin-1;化合物 Hongotoxin-1Hongotoxin-1
Hongotoxin-1, a chemical compound isolated from the venom of Centruroides limbatus, functions as a potassium channel inhibitor. It exhibits inhibitory concentrations (IC50) for potassium channel subtypes Kv1.1, Kv1.2, Kv1.3, and Kv1.6 at 31 pM, 170 pM, 86 pM, and 6000 pM, respectively [1].
价 格:¥电议型 号:T80061产 地:中国大陆
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T80033Biotin-α-Bungarotoxin;化合物 Biotin-α-BungarotoxinBiotin-α-Bungarotoxin
Biotin-α-Bungarotoxin is a biotinylated form of α-Bungarotoxin, which acts as a competitive antagonist at nicotinic acetylcholine receptors (nAChRs) [1].
价 格:¥电议型 号:T80033产 地:中国大陆
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T80032FITC-α-Bungarotoxin;化合物 FITC-α-BungarotoxinFITC-α-Bungarotoxin
FITC-α-Bungarotoxin is the FITC-labeled form of α-Bungarotoxin, which acts as a competitive antagonist at nicotinic acetylcholine receptors (nAChRs) [1].
价 格:¥电议型 号:T80032产 地:中国大陆
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T80022(R)-tert-OMe-byakangelicin;化合物 (R)-tert-OMe-byakangelicin(R)-tert-OMe-byakangelicin
(R)-tert-OMe-byakangelicin, a furanocoumarin, exhibits inhibitory effects on liver drug metabolizing enzyme (DME) activity and can be isolated from the immature fruits of Angelica sinensis [1] [2].
价 格:¥电议型 号:T80022产 地:中国大陆
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T79991Condurango glycoside A;化合物 Condurango glycoside ACondurango glycoside A
Condurango glycoside A activates p53, induces ROS generation, up-regulates p53 expression, and triggers apoptosis as well as premature senescence associated with DNA damage in HeLa cells [1].
价 格:¥电议型 号:T79991产 地:中国大陆
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T79987Cangorinine E-1;化合物 Cangorinine E-1Cangorinine E-1
Cangorinine E-1 (compound 11), a dihydroagarofuran sesquiterpenoid derivative, exhibits weak inhibitory effects on herpes simplex virus type II (HSV) [1].
价 格:¥电议型 号:T79987产 地:中国大陆
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T7995α-Angelica lactone;α-当归内酯Alpha-Angelica Lactone;α-当归内酯|||当归内酯|||Alpha-Angelica Lactone
α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.
价 格:¥电议型 号:T7995产 地:中国大陆
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T79930Sanggenon A;桑根酮ASanggenone A;Sanggenone A
Sanggenon A (Sanggenone A) exhibits anti-inflammatory properties by modulating the NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells, and it significantly suppresses Lipopolysaccharide (LPS)-induced nitric oxide production [1].
价 格:¥电议型 号:T79930产 地:中国大陆
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T79873TNG-462;化合物 TNG-462TNG-462
TNG-462 (Compound 1143) is a PRMT5 inhibitor with oral activity, being investigated for use in MTAP-deficient and/or MTA-accumulating cancers [1].
价 格:¥电议型 号:T79873产 地:中国大陆
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T79854Lingdolinurad;化合物 LingdolinuradLingdolinurad
Lingdolinurad is a uric acid transporter protein inhibitor targeting hURAT1 for the study of hyperuricemia or gout.
价 格:¥电议型 号:T79854产 地:中国大陆
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T79759Antifungal agent 74;化合物 Antifungal agent 74Antifungal agent 74
Antifungal agent 74 (compound 3c), is a potent substance that exhibits excellent fungicidal activity against C. arachidicola and R. solani, functioning by disrupting steroid biosynthesis and ribosome biogenesis in eukaryotes [1].
价 格:¥电议型 号:T79759产 地:中国大陆
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T79589Antifungal agent 71;化合物 Antifungal agent 71Antifungal agent 71
Antifungal agent 71 (compound 6r), a trifluoromethyl pyrimidine derivative, displays potent in vitro activity against F. oxysporum, evidenced by an EC 50 value of 3.61 μg/mL [1].
价 格:¥电议型 号:T79589产 地:中国大陆
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T79552Antifungal agent 70;化合物 Antifungal agent 70Antifungal agent 70
Antifungal Agent 70 (Compound 13), a dihydroeugenol-imidazole, exhibits efficacy against multi-resistant Candida auris with a minimum inhibitory concentration (MIC) of 36.4 μM, demonstrating notable antifungal activity [1].
价 格:¥电议型 号:T79552产 地:中国大陆
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T79551Antifungal agent 69;化合物 Antifungal agent 69Antifungal agent 69
Antifungal agent 69 (compound 13), a eugenol-imidazole derivative, demonstrates targeted activity against Candida albicans with a minimum inhibitory concentration (MIC) of 4.6 μM, while exhibiting negligible cytotoxicity. This compound disrupts ergosterol biosynthesis, contributing to its antifungal efficacy [1].
价 格:¥电议型 号:T79551产 地:中国大陆
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T79550Antifungal agent 68;化合物 Antifungal agent 68Antifungal agent 68
Antifungal agent 68 (compound 10) effectively combats fungal infections caused by Candida and Cryptococcus gattii through the inhibition of ergosterol biosynthesis, likely via interaction with lanosterol 14α-demethylase (CYP51). It is proposed that the imidazole ring of antifungal agent 68 interacts with the heme group of CYP51 [1].
价 格:¥电议型 号:T79550产 地:中国大陆
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T79549Antifungal agent 67;化合物 Antifungal agent 67Antifungal agent 67
Compound 9 (Antifungal agent 67), an imidazole class antifungal, exhibits efficacy against Candida and possesses a CC50 value of 33.6 μM in neonatal rat cardiomyoblasts [1].
价 格:¥电议型 号:T79549产 地:中国大陆
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T79545Antifungal agent 66;化合物 Antifungal agent 66Antifungal agent 66
Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects on the spores of B. cinerea, with an IC50 value of 47.7 μg/mL [1].
价 格:¥电议型 号:T79545产 地:中国大陆
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T79522Antifungal agent 65;化合物 Antifungal agent 65Antifungal agent 65
Compound 5d (Antifungal Agent 65) exhibits potent fungicidal activity against Fusarium oxysporum f.sp. cucumerinum and is utilized in antiviral and fungicidal research [1].
价 格:¥电议型 号:T79522产 地:中国大陆
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T79521Antifungal agent 64;化合物 Antifungal agent 64Antifungal agent 64
Compound 5c (Antifungal agent 64) exhibits potent fungicidal activity against Fusarium oxysporum f.sp. cucumerinum and is applicable for research in antiviral and fungicidal domains [1].
价 格:¥电议型 号:T79521产 地:中国大陆
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T79508Microtubule stabilizing agent-1;化合物 Microtubule stabilizing agent-1Microtubule stabilizing agent-1
Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [1].
价 格:¥电议型 号:T79508产 地:中国大陆