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T18515Palbociclib-propargyl；化合物 T18515PROTAC CDK6 ligand 1；PROTAC CDK6 ligand 1
Palbociclib-propargyl, a PROTAC ligand targeting the protein CDK6, connects to the CRBN ligand through a PEG linker to form PROTAC CP-10. CP-10 exhibits a potent DC50 value of 2.1 nM against CDK6[1].
价 格：￥电议型 号：T18515产 地：中国大陆
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T18451N-methyl-N’-methyl-O-(m-PEG4)-O’-(propargyl-PEG4)-Cy5；化合物 T18451n-methyl-n-methyl-o-m-peg4-o-proparg
N-methyl-N´-methyl-O-(m-PEG4)-O´-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T18451产 地：中国大陆
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T18450N-methyl-N’-methyl-O-(m-PEG4)-O’-(propargyl-PEG4)-Cy3；化合物 T18450n-methyl-n-methyl-o-m-peg4-o-proparg
N-methyl-N´-methyl-O-(m-PEG4)-O´-(propargyl-PEG4)-Cy3 is a polyethylene glycol (PEG)-based linker used for the synthesis of proteolysis targeting chimeras (PROTACs) [1].
价 格：￥电议型 号：T18450产 地：中国大陆
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T18432N-(m-PEG4)-N’-(m-PEG4)-O-(m-PEG4)-O’-(propargyl-PEG4)-Cy5；化合物 T18432n-m-peg4-n-m-peg4-o-m-peg4-o-pro
N-(m-PEG4)-N´-(m-PEG4)-O-(m-PEG4)-O´-(propargyl-PEG4)-Cy5 serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs[1].
价 格：￥电议型 号：T18432产 地：中国大陆
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T18288Mal-?PEG4-?propargyl；化合物 T18288Mal-?PEG4-?propargyl
Mal- PEG4- propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
价 格：￥电议型 号：T18288产 地：中国大陆
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T1827Buparlisib；布帕尼西BKM120|||NVP-BKM120；BKM120|||布帕尼西|||NVP-BKM120
Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).
价 格：￥电议型 号：T1827产 地：中国大陆
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T18199m-PEG37-Propargyl；化合物 T18199m-PEG37-Propargyl
m-PEG37-Propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18199产 地：中国大陆
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T18189m-PEG3-Sulfone-PEG4-propargyl；化合物 T18189m-PEG3-Sulfone-PEG4-propargyl
m-PEG3-Sulfone-PEG4-propargyl is a polyethylene glycol (PEG)-based prodrug-induced degradation (PROTAC) linker. It is utilized in the efficient synthesis of PROTACs, a class of heterobifunctional molecules designed to selectively target and degrade specific protein targets[1].
价 格：￥电议型 号：T18189产 地：中国大陆
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T18183m-PEG3-S-PEG4-propargyl；化合物 T18183m-PEG3-S-PEG4-propargyl
m-PEG3-S-PEG4-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18183产 地：中国大陆
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T18176m-PEG25-Propargyl；化合物 T18176m-PEG25-Propargyl
m-PEG25-Propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18176产 地：中国大陆
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T18070Lenalidomide-propargyl-C2-NH2 hydrochloride；化合物 T18070Lenalidomide-propargyl-C2-NH2 hydrochloride
Lenalidomide-propargyl-C2-NH2 hydrochloride is a compound that features a cereblon (CRBN) ligand for the E3 ubiquitin ligase, as well as a linker. It is utilized in the development of the PROTAC MD-224[1] system.
价 格：￥电议型 号：T18070产 地：中国大陆
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T18069Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride；化合物 T18069Lenalidomide-propargyl-C2-amido-Ph-NH
Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride is a chemical compound that features a cereblon (CRBN) ligand, functioning as an E3 ubiquitin ligase, along with a linker. It can be utilized to create the PROTAC MD-224[1].
价 格：￥电议型 号：T18069产 地：中国大陆
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T17866DSPE-PEG5-propargyl；化合物 T17866DSPE-PEG5-propargyl
DSPE-PEG5-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17866产 地：中国大陆
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T1780LParecoxib sodium帕瑞昔布钠SC 69124A|||SC-69124A|||帕瑞昔布钠|||SC69124A|||Dynastat
Parecoxib is a cyclooxygenase-2 inhibitor used for the short-term treatment of postoperative pain in adults. Parecoxib is a water-soluble and injectable prodrug of valdecoxib. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib and rofecoxib. ketorolac has a much higher gastrointestinal toxicity profile compared to most other nonsteroidal anti-inflammatory drugs including ibuprofen and Naprosyn.
价 格：￥电议型 号：T1780L产 地：中国大陆
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T1780Parecoxib；帕瑞昔布SC 69124|||Vorth-P|||Valus-P；SC 69124|||帕瑞昔布|||Vorth-P|||Valus-P
Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.
价 格：￥电议型 号：T1780产 地：中国大陆
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T17700Bromoacetamide-PEG3-propargyl；化合物 T17700Bromoacetamide-PEG3-propargyl
Bromoacetamide-PEG3-propargyl is a polyethylene glycol (PEG) derived linker utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17700产 地：中国大陆
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T1769Pardoprunox；帕多芦诺SLV-308|||DU-126891；帕多芦诺|||SLV-308|||DU-126891
Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson´s Disease and Advanced Stage Parkinson´s Disease.
价 格：￥电议型 号：T1769产 地：中国大陆
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T17685Boc-NH-PEG9-propargyl；化合物 T17685Boc-NH-PEG9-propargyl
Boc-NH-PEG9-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17685产 地：中国大陆
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T17669Boc-NH-PEG12-propargyl；化合物 T17669Boc-NH-PEG12-propargyl
Boc-NH-PEG12-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17669产 地：中国大陆
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T17641Boc-aminooxy-amide-PEG4-propargyl；化合物 T17641Boc-aminooxy-amide-PEG4-propargyl
Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4-unit polyethylene glycol (PEG) linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T17641产 地：中国大陆
