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T63536Dual FAAH/sEH-IN-1
Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.
价 格:¥电议型 号:T63536产 地:中国大陆
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T7406AKR1C3-IN-1AKR-1C3-IN-1,inhibit,AKR1C3IN1,AKR1C3 IN 1,Inhibitor
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
价 格:¥电议型 号:T7406产 地:中国大陆
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T10954DAGLβ-IN-1DAGLβIN1,DAGLβ IN 1
DAGLβ-IN-1 is a universal intermediate for designing DAGL tailored activity-based probes, and is an inhibitor of diacylglycerol lipase-β (DAGLβ).
价 格:¥电议型 号:T10954产 地:中国大陆
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T9103BVDV-IN-1inhibit,virus,non-nucleoside,BVDV IN 1,activity,bovine,viral,antiviral,inhibitor,BVDVIN1,DN
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC).
价 格:¥电议型 号:T9103产 地:中国大陆
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T9094JMJD7-IN-1Inhibitor,Histone Demethylase,cancer,JMJD7,JMJD7 IN 1,inhibit,JMJD7IN1,JMJD-7-IN-1
JMJD7-IN-1 is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7.
价 格:¥电议型 号:T9094产 地:中国大陆
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T10033COX-2-IN-1COX 2 IN 1,COX2IN1
COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).
价 格:¥电议型 号:T10033产 地:中国大陆
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T11158EGFR-IN-11EGFRIN11,EGFR IN 11
EGFR-IN-11 is a selective inhibitor of EGFR-tyrosine kinase and induces cell apoptosis. EGFR-IN-11 inhibits triple mutant EGFRL858R/T790M/C797S with an IC50 of 18 nM and arrests cell cycle at G0/G1.
价 格:¥电议型 号:T11158产 地:中国大陆
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T6014911β-HSD1-IN-1111βHSD1IN11
11β-HSD1-IN-11 is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively.
价 格:¥电议型 号:T60149产 地:中国大陆
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T11024DHODH-IN-15DHODH IN 15,DHODHIN15
DHODH-IN-15 is the hydroxyfuran analogue of A771726. DHODH-IN-15 is a dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 11 μM for rat liver DHODH. DHODH-IN-15 can be used for rheumatoid arthritis.
价 格:¥电议型 号:T11024产 地:中国大陆
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T9564IRE1α kinase-IN-1endoribonuclease,Inositol requiring enzyme 1,cells,IRE1,oligomerization,IRE-1α kina
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosphorylation, and also inhibits IRE1α RNase activity (IC50=80 nM)
价 格:¥电议型 号:T9564产 地:中国大陆
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T9305Necroptosis-IN-1NecroptosisIN1,RIP kinase,Inhibitor,inhibit,Necroptosis,RIPK,Necroptosis IN 1,Recept
Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.
价 格:¥电议型 号:T9305产 地:中国大陆
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T8587EcDsbB-IN-12EcDsbBIN12,EcDsbB IN 12
EcDsbB-IN-12 targets disulfide bond forming enzyme,and is a novel potent specific inhibitor of EcDsbB.
价 格:¥电议型 号:T8587产 地:中国大陆
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T9697ASK1-IN-1CNS,inhibit,p38 MAPK,ASK1,ASK-1-IN-1,ASK1 IN 1,ASK1IN1,MAPK,Inhibitor,brain,penetrant
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.
价 格:¥电议型 号:T9697产 地:中国大陆
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T10682LCARM1-IN-1
CARM1-IN-1 is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.
价 格:¥电议型 号:T10682L产 地:中国大陆
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TQ0256FGFR4-IN-1Fibroblast growth factor receptor,FGFR-4-IN-1,FGFR,inhibit,FGFR4IN1,Inhibitor,FGFR4 IN 1
FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
价 格:¥电议型 号:TQ0256产 地:中国大陆
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T8917PAR-2-IN-1Inhibitor,PAR2IN1,anti-inflammatory,anticancer,PAR 2 IN 1,inhibit,PAR2,Thrombin receptors,
IUN76750 is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.
价 格:¥电议型 号:T8917产 地:中国大陆
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T60077SCP1-IN-1SCP1 IN 1,SCP1IN1
SCP1-IN-1 (compound SH T-62) is a potent and selective covalent inhibitor against SCP1. SCP1-IN-1 promotes REST degradation and reduces transcriptional activity. In some glioblastoma cells, the high level of REST protein drives tumor growth. SCP1-IN-1 has the potential for the research of glioblastoma whose growth is driven by REST transcription activity [1].
价 格:¥电议型 号:T60077产 地:中国大陆
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T8555Neuraminidase-IN-1virus,Influenza Virus,inhibit,A/WSN/33H1N1,Inhibitor,influenza,neuraminidase,H1N1,
Compound Y-1 is a novel neuraminidase inhibitor.
价 格:¥电议型 号:T8555产 地:中国大陆
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T11157LEGFR-IN-1 hydrochlorideEGFRIN1 hydrochloride,EGFR IN 1 hydrochloride
EGFR-IN-1 hydrochloride is an irreversible and specific inhibitor of L858R/T790M mutant EGFR with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 hydrochloride exhibits potent antitumor and antiproliferative activity in H1975 cells and the mutant HCC827 cells with IC50s of 4 and 28 nM, respectively.
价 格:¥电议型 号:T11157L产 地:中国大陆
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T10827CK2/ERK8-IN-1
CK2/ERK8-IN-1 is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 ?M) and ERK8 (IC50s: 0.50 μM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds to PIM1, DYRK1A, and HIPK2 (Kis: 8.65 ?M, 11.9 ?M, and 15.25 ?M).
价 格:¥电议型 号:T10827产 地:中国大陆