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T36680SM1-71;化合物 SM1-71SM1-71
SM1-71 is a potent multi-targeted acrylamide-modified TAK1 inhibitor that inhibits MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2.SM1-71 can be used as a kinase probe with anticancer activity and inhibits the proliferation of various cancer cell lines.
价 格:¥电议型 号:T36680产 地:中国大陆
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T3445LImportazole HCl (662163-81-7 free base);化合物 T3445LImportazole hydrochloride|||Importazole HCl|||Impo
Importazole specifically inhibits the importin-β likely by altering its interaction with RanGTP.
价 格:¥电议型 号:T3445L产 地:中国大陆
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T34369RO-11-7330;化合物 T34369RO11-7330|||RO-117330;RO11-7330|||RO-117330
RO-11-7330 is a bioactive chemical.
价 格:¥电议型 号:T34369产 地:中国大陆
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T32106Human beta-amyloid protein 42 (1-7);化合物 T32106Vanutide;Vanutide
Human beta-amyloid protein 42 (1-7) is a bioactive chemical.
价 格:¥电议型 号:T32106产 地:中国大陆
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T31644Enviroxime;化合物 T31644LY-122772|||LY 122772|||LY122772|||LY122771-72|||NSC 346230;LY-122772|||LY 1227
Enviroxime(LY 122772, NSC 346230) is an anti-infective and anti-disease agent. Enviroxime targets the 3A coding region of rhinovirus and poliovirus.
价 格:¥电议型 号:T31644产 地:中国大陆
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T28583Ro 31-7837;化合物 T28583Ro-31-7837|||Ro 317837;Ro-31-7837|||Ro 317837
Ro 31-7837 is an opener of potassium channel.
价 格:¥电议型 号:T28583产 地:中国大陆
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T26554Aclerastide;化合物 T26554DSC-127|||DSC 127|||NorLeu-3-A(1-7)|||DSC127|||NorLeu-3A(1-7);DSC-127|||DSC 12
Aclerastide is an angiotensin receptor agonist. Administration of Aclerastide reduced fibrosis and scarring in the healing wounds. This action was more pronounced with longer administration of the peptide after injury. The action of this peptide was blocked by the AT receptor antagonist d-Ala7-angiotensin(1-7), which suggests that this receptor is involved in the healing responses to exogenous Aclerastide.
价 格:¥电议型 号:T26554产 地:中国大陆
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T23177PPACK Dihydrochloride (71142-71-7 free base);化合物 T23177PPACK Dihydrochloride;PPACK Dihydrochloride
PPACK Dihydrochloride is the dihydrochloride form of its active component PPACK (D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone), a potent, selective, and irreversible inhibitor of thrombin that inhibits human α-thrombin with inhibition constant (Ki: 0.24 nM).
价 格:¥电议型 号:T23177产 地:中国大陆
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T23076LNociceptin (1-7) acetate;化合物Nociceptin (1-7) acetateNociceptin (1-7) acetate
Nociceptin (1-7) acetate is a potent agonist of opioid receptor-like 1 (ORL1) receptor. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia and has antinociceptive activity.
价 格:¥电议型 号:T23076L产 地:中国大陆
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T23076Nociceptin(1-7);化合物 T23076Nociceptin (1-7);Nociceptin (1-7)
Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesia
价 格:¥电议型 号:T23076产 地:中国大陆
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T22575Angiotensin Fragment 1-7 (acetate);化合物 T22575Angiotensin Fragment 1-7 (acetate)
Angiotensin Fragment 1-7 is a type 1 angiotensin II receptor agonist. In the renin-angiotensin system, angiotensin I is cleaved by the angiotensin-converting enzyme to form angiotensin II, which has effects on fluid and electrolyte, as well as homeostasis blood pressure.
价 格:¥电议型 号:T22575产 地:中国大陆
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T22572Angiotensin 1/2 (1-7) amide;化合物 T22572Angiotensin 1/2 (1-7) amide
Angiotensin I/II (1-7) amide is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse. Angiotensin I/II amide is an amide derivative of angiotensin II that is a powerful vasoconstrictor and vasopressor and is used in the treatment of certain hypotensive states. Angiotensin I/II amide is usually administered by slow intravenous infusion, and sometimes intramuscularly or subcutaneously.
价 格:¥电议型 号:T22572产 地:中国大陆
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T1934Bay 11-7085;化合物Bay 11-7085BAY 11-7083;BAY 11-7083
Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
价 格:¥电议型 号:T1934产 地:中国大陆
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T1902BAY 11-7082化合物BAY 11-7082BAY 11-7821
BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM). BAY 11-7082 is also an inhibitor of the ubiquitin-specific proteases USP7 and USP21 (IC50=0.19/0.96 μM).
价 格:¥电议型 号:T1902产 地:中国大陆
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T13759LTX-401 dihydrochloride (1262851-70-6 free base);化合物 T13759LTX-401 dihydrochloride;LTX-401 dihydroch
LTX-401, targets the Golgi apparatus, and is an oncolytic amino acid derivative.
价 格:¥电议型 号:T13759产 地:中国大陆
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T13049LSynucleozid hydrochloride (502139-01-7 free base);化合物 T13049LSynucleozid hydrochloride|||NSC 377363
Synucleozid hydrochloride is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.
价 格:¥电议型 号:T13049L产 地:中国大陆
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T1281Tropicamide托吡卡胺Ro 1-7683|||托吡卡胺
Tropicamide (Ro 1-7683) is a synthetic muscarinic antagonist with actions similar to atropine and with an anticholinergic property. Upon ocular administration, tropicamide binds to and blocks the muscarinic receptors in the sphincter and ciliary muscle in the eye. This inhibits the responses from cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle. Tropicamide is a diagnostic agent and is used to produce short-duration mydriasis and cycloplegia.
价 格:¥电议型 号:T1281产 地:中国大陆
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T10549Bisindolylmaleimide VIII acetate;化合物Bisindolylmaleimide VIII acetateRo 31-7549 acetate|||Bis VIII ac
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC). It has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively.
价 格:¥电议型 号:T10549产 地:中国大陆