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T7798FGH10019;化合物FGH-10019FGH-10019;FGH-10019
FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).
价 格:¥电议型 号:T7798产 地:中国大陆
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T77939WBC100;化合物 WBC10014-D-Valine-TPL;14-D-Valine-TPL
WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathway, primarily utilized in research for c-Myc overexpressing tumors [1].
价 格:¥电议型 号:T77939产 地:中国大陆
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T7741DS-1001b;化合物DS-1001bDS-1001b
DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)
价 格:¥电议型 号:T7741产 地:中国大陆
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T72216DPM-1001 trihydrochloride;化合物 DPM-1001 trihydrochlorideDPM-1001 trihydrochloride
DPM-1001 trihydrochloride, an analog of the specific protein-tyrosine phosphatase (PTP1B) inhibitor MSI-1436, is a potent, specific, non-competitive, orally active inhibitor of PTP1B with an IC50 of 100 nM, exhibiting anti-diabetic properties.
价 格:¥电议型 号:T72216产 地:中国大陆
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T71001GSK-598809;化合物 GSK-598809GSK-598809
GSK598809 is a selective D(3)R antagonist recently progressed in Phase I trials. GSK-598809 may decrease the rewarding effects of contextual cues associated with drug intake preclinically, which may reduce drug craving in humans.
价 格:¥电议型 号:T71001产 地:中国大陆
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T70987AT-1001;化合物 AT-1001AT-1001
AT-1001 is an α3β4 nAChR partial agonist. AT-1001 attenuates stress-induced reinstatement of nicotine seeking in a rat model of relapse and induces minimal withdrawal in dependent rats. AT-1001 also potently and reversibly blocks epibatidine-induced inward currents in HEK cells transfected with α3β4 nAChR. Importantly, AT-1001 potently and dose-dependently blocks nicotine self-administration in rats, without affecting food responding. When tested in a nucleus accumbens (NAcs) synaptosomal prepar
价 格:¥电议型 号:T70987产 地:中国大陆
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T70986GL-1001 sodium salt;化合物 GL-1001 sodium saltGL-1001 sodium salt
GL-1001 sodium salt is an ACE2 inhibitor.
价 格:¥电议型 号:T70986产 地:中国大陆
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T70985GL-1001 disodium tetrahydrate;化合物 GL-1001 disodium tetrahydrateGL-1001 disodium tetrahydrate
GL-1001 disodium tetrahydrate is an ACE2 inhibitor.
价 格:¥电议型 号:T70985产 地:中国大陆
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T70698MDL-100173;化合物 MDL-100173MDL-100173
MDL-100173 is a dual angiotensin-converting enzyme (ACE)/neutral endopeptidase (NEP) inhibitor.
价 格:¥电议型 号:T70698产 地:中国大陆
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T70113ATM-1001;化合物 ATM-1001ATM-1001
ATM-1001 is an inhibitor of the cancer-associated tropomyosin 3.1 (Tpm3.1), suppressing glucose-stimulated insulin secretion (GSIS) from the pancreatic islets.
价 格:¥电议型 号:T70113产 地:中国大陆
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T6922ORY1001;化合物ORY1001RG-6016|||ORY-1001 (RG-6016) 2HCl|||ORY-1001|||ORY 1001;RG-6016|||ORY-1001 (RG-601
ORY1001 (ORY 1001) is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor, with high selectivity against related FAD dependent aminoxidases with IC50 of <20 nM.
价 格:¥电议型 号:T6922产 地:中国大陆
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T69185INO-1001 methanesulfonate;化合物 INO-1001 methanesulfonateINO-1001 methanesulfonate
INO-1001 methanesulfonate is an isoindolinone derivative and potent inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with chemosensitization and radiosensitization properties.
价 格:¥电议型 号:T69185产 地:中国大陆
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T69080T1001;化合物 T1001T1001
T1001 is an antagonist of hypoxia-inducible factor-2α subunit (HIF-2α) which displaces residue M252 from inside the HIF-2α PAS-B pocket toward the ARNT subunit to weaken heterodimerization.
价 格:¥电议型 号:T69080产 地:中国大陆
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T67970GPX-100;化合物GPX-10013-deoxydoxorubicin;13-deoxydoxorubicin
GPX-100 (13-deoxydoxorubicin) is an analogue of the anthracycline antitumour antibiotic doxorubicin. GPX-100 inserts into DNA and interacts with topoisomerase II to inhibit DNA replication and repair as well as RNA and protein synthesis.
价 格:¥电议型 号:T67970产 地:中国大陆
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T64167Ifebemtinib;化合物 IfebemtinibIN-10018|||BI-853520;IN-10018|||BI-853520
Ifebemtinib (BI-853520) is an orally active and potent inhibitor of adhesion plaque kinase (FAK) (IC50=1 nM) with anti-tumour activity that inhibits globule formation and in situ tumour growth in malignant pleural mesotheliomas, and may be useful for the study of breast and ovarian cancer.
价 格:¥电议型 号:T64167产 地:中国大陆
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T6407β-Lapachone;化合物Beta-LapachoneBeta-Lapachone|||NSC-26326|||SL-11001|||ARQ-501;3,4-二氢-2,2-二甲基-2H-萘并[1,
β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.
价 格:¥电议型 号:T6407产 地:中国大陆
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T63293-Aminobenzamide;化合物INO10013-AB|||INO1001|||INO-1001|||3-ABA|||PARP-IN-1|||INO 1001;3-AB|||INO1001||
3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during reperfusion.
价 格:¥电议型 号:T6329产 地:中国大陆
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T62527INO-1001;化合物 INO-1001INO-1001
INO-1001 is a potent, selective poly(ADP-ribose) polymerase (PARP) inhibitor with antitumor activity.INO-1001 is a potent radiosensitization enhancer that uses interference with DNA repair mechanisms to enhance radiation-induced cell killing and necrotic cell death.
价 格:¥电议型 号:T62527产 地:中国大陆
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T61001Antiparasitic agent-6;化合物 Antiparasitic agent-6Antiparasitic agent-6
Antiparasitic agent-6 (compound 5b) shows selectively antiparasitic activity against Leishmania infantum (L. infantum) (IC 50 = 3.89 μM). Antiparasitic agent-6 also exhibits certain cytotoxicity against HepG2 with a CC50 value of 13.64 μM [1].
价 格:¥电议型 号:T61001产 地:中国大陆