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T16156MT 63-78
MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63–78 also causes cell mitotic arrest and apoptosis.
价 格:¥电议型 号:T16156产 地:中国大陆
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T15697L-NMMA acetateTilarginine acetate;Methylarginine acetate
L-NMMA acetate is an inhibitor of nitric oxide synthase of all NOS isoforms (i.e. NOS1, NOS2, and NOS3). The Ki values are 0.18, 0.4, and 6 ?M for nNOS, eNOS, and iNOS, respectively.
价 格:¥电议型 号:T15697产 地:中国大陆
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T1569TigecyclineGAR-936;替加环素
Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.
价 格:¥电议型 号:T1569产 地:中国大陆
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T15686L-7416263-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole
L-741626 is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively).
价 格:¥电议型 号:T15686产 地:中国大陆
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T15681L-161982
L-161982 is a selective EP4 receptor antagonist. L-161982 decreases collagen-induced arthritis in mice. L-161982 fully blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells.
价 格:¥电议型 号:T15681产 地:中国大陆
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T1568AmoxapineCL-67772;阿莫沙平
Amoxapine exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve endings and blocks the response of dopamine receptors to dopamine. Amoxapine is a tricyclic antidepressant
价 格:¥电议型 号:T1568产 地:中国大陆
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T15677KY1220
KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.
价 格:¥电议型 号:T15677产 地:中国大陆
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T15675Tirbanibulin MesylateKX2-391 Mesylate;KX01 Mesylate
Tirbanibulin Mesylate is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).
价 格:¥电议型 号:T15675产 地:中国大陆
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T1567Olanzapine奥氮平;LY170053
Olanzapine is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
价 格:¥电议型 号:T1567产 地:中国大陆
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T15660KHK-IN-1KHK-IN-8;Ketohexokinase inhibitor 8
KHK-IN-1 is a reversible and ATP-competitive inhibitor of ketohexokinase (KHK) with IC50 of 12 nM. In the ATP-binding region of KHK, KHK-IN-1 interacts with Asp-27B.
价 格:¥电议型 号:T15660产 地:中国大陆
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T1566Aripiprazole阿立哌唑;OPC-14597
Aripiprazole is an antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of
价 格:¥电议型 号:T1566产 地:中国大陆
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T15656KGA-2727
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 for the treatment of diabete.
价 格:¥电议型 号:T15656产 地:中国大陆
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T15654Ketohexokinase inhibitor 1
Ketohexokinase inhibitor 1 is a ketohexokinase inhibitor (IC50s: 8.4 nM and 66 nM for KHK-C and KHK-A, respectively).
价 格:¥电议型 号:T15654产 地:中国大陆
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T1565DeferiproneCP20;Deferidone;去铁酮
Deferiprone is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.
价 格:¥电议型 号:T1565产 地:中国大陆
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T15649KDM5-IN-1
KDM5-IN-1 is an effective and selective inhibitor of KDM5 with an IC50 of 15.1 nM.
价 格:¥电议型 号:T15649产 地:中国大陆
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T15646KBU2046
KBU2046 is an oral inhibitor of cell motility and cell invasion in vitro. KBU2046 inhibits cancer metastasis and prolongs life. KBU2046 binds chaperone heterocomplexes, selectively alters binding of client proteins that regulate motility, and lacks all of
价 格:¥电议型 号:T15646产 地:中国大陆
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T1564CisplatinCDDP;cis-Diaminodichloroplatinum;顺铂
Cisplatin, a DNA-crosslinking agent, is able to suppress DNA synthesis by conforming DNA adducts in cancer cells.
价 格:¥电议型 号:T1564产 地:中国大陆
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T15639K-756
K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 (IC50 = 31 nM) and TNKS2 (IC50 = 36 nM).
价 格:¥电议型 号:T15639产 地:中国大陆