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  • T6647Rotigotine-Rotigotine,dopamine,5-HT1A,Adrenergic Receptor,receptor,N0923,Serotonin Receptor,N 0923,5

    Rotigotine is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily transdermal patch, Rotigotine has not been associated with serum enzyme elevations during treatment or with episodes of clinically apparent liver injury.

    价 格：￥电议型 号：T6647产 地：中国大陆

  • TQ0311GSK163090Dopamine Receptor,5-HT1A,GSK163090,Inhibitor,5-hydroxytryptamine Receptor,antidepressant,an

    GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).

    价 格：￥电议型 号：TQ0311产 地：中国大陆

  • T9552BAZ1A-IN-1leukemia,breast cancer,Epigenetic Reader Domain,BAZ1A IN 1,cancer,ZR-75–30,BAZ1A,BAZ1AIN1,

    BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-survival activity against cancer cell lines with high BAZ1A expression, but weak or no activity against cancer cells with low BAZ1A expression.

    价 格：￥电议型 号：T9552产 地：中国大陆

  • T8780AMG131AMG131,proliferator,inhibit,Inhibitor,activated,Peroxisome proliferator-activated receptors,IN

    INT-131, is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin dependent diabetes)

    价 格：￥电议型 号：T8780产 地：中国大陆

  • T601264-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-meth

    4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.

    价 格：￥电议型 号：T60126产 地：中国大陆

  • T6339AG14361AG-14361；AG 14361

    AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).

    价 格：￥电议型 号：T6339产 地：中国大陆

  • T6080NVP-AEW541AEW541

    NVP-AEW541, a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based assay.

    价 格：￥电议型 号：T6080产 地：中国大陆

  • T5456WNK-IN-11Allosteric WNK Kinase Inhibitor

    WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)

    价 格：￥电议型 号：T5456产 地：中国大陆

  • T5301NSC 8751alpha-butenoic acid；Crotonic acid；巴豆酸

    Crotonic acid is fatty acid formed by the action of fatty acid synthases from acetyl-CoA and malonyl-CoA precursors. It is involved in the fatty acid biosynthesis. It is also found in water extracts from carrot seeds (Daucus carota L.).

    价 格：￥电议型 号：T5301产 地：中国大陆

  • T4529ASP-9521ASP9521；ASP 9521

    ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).

    价 格：￥电议型 号：T4529产 地：中国大陆

  • T4380Ac-CoA Synthase Inhibitor1ACSS2 inhibitor

    ACSS2 inhibitor is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).

    价 格：￥电议型 号：T4380产 地：中国大陆

  • T4125HSF1A

    HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.

    价 格：￥电议型 号：T4125产 地：中国大陆

  • T4100AS8351AS 8351；NSC51355；AS-8351

    AS-8351 is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A 83-01, BIX01294, SC-1, Y-27632, OAC2, SU 16f, and JNJ-10198409 to induce reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.

    价 格：￥电议型 号：T4100产 地：中国大陆

  • T37792A2A receptor antagonist 1A2A receptor antagonist 1

    A2A receptor antagonist 1 is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively.

    价 格：￥电议型 号：T37792产 地：中国大陆

  • T3540IMR-1A

    IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.

    价 格：￥电议型 号：T3540产 地：中国大陆

  • T3224TBA-7371AZ 7371；DprE1-IN-1

    DprE1-IN-1 is a potent inhibitor of DprE1 and PDE6.

    价 格：￥电议型 号：T3224产 地：中国大陆

  • T3032VE-821ATR Inhibitor IV；VE 821；VE821

    VE-821 is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).

    价 格：￥电议型 号：T3032产 地：中国大陆

  • T3031A 83-01ALK5 Inhibitor IV

    A 83-01 is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 with IC50 values of 12 nM, 45 nM and 7.5 nM, respectively.

    价 格：￥电议型 号：T3031产 地：中国大陆

  • T26690AVN-101AVN 101；AVN101

    AVN-101 is a very potent 5-HT7 receptor antagonist (Ki = 153 pM). AVN-101 also exhibits a rather high affinity toward histamine H1 (Ki = 0.58 nM) and adrenergic α2A, α2B, and α2C (Ki = 0.41-3.6 nM) receptors. AVN-101 shows a good oral bioavailability and

    价 格：￥电议型 号：T26690产 地：中国大陆

  • T2662Alda-1Alda 1

    Alda-1 is an ALDH2 agonist, a cell-permeable activator of both the wild-type ALDH2*1 and the Asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2).

    价 格：￥电议型 号：T2662产 地：中国大陆

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