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T9123DS-1205TRKA,c-Met/HGFR,migration,Axl,Tyro3,Trk Receptor,MET,DS 1205,Mer,Tropomyosin related kinase r
DS-1205 is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205 also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205 can inhibit cell migration in vitro and tumor growth in vivo[1].
价 格:¥电议型 号:T9123产 地:中国大陆
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T8842IMT1BInhibitor,inhibit,POLRMT,oxidative,IMT-1B,LDC-203974,human,LDC 203974,anti-tumour,mtDNA,phospho
IMT1B is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. It has anti-tumour effects.
价 格:¥电议型 号:T8842产 地:中国大陆
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T60205(2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide(2S)4biphenyl4ylNhydroxy2methyl2
(2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide is a LpxC inhibitor with IC50 >95.2 nM.
价 格:¥电议型 号:T60205产 地:中国大陆
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T10201PDE IV-IN-1PDE IVIN1,PDE IV IN 1
PDE IV-IN-1 is a phosphodiesterase IV inhibitor used for the research of COPD, asthma, or other inflammatory diseases.
价 格:¥电议型 号:T10201产 地:中国大陆
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T7200TAK-960Polo-like Kinase (PLK),cell,cancer,proliferation,Inhibitor,mitosis,TAK960,TAK 960,leukemia,in
TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.
价 格:¥电议型 号:T7200产 地:中国大陆
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TN1420Bacopaside Iinhibit,Inhibitor,Bacopaside I
Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer´s disease, it ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of α2-amyloid,exbibits antioxidant properties and free radical scavenging capacity and exerts antidepressant-like effect.
价 格:¥电议型 号:TN1420产 地:中国大陆
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T9765TJ-M2010-5ischemia,MIRI,Anoxia,factor,MyD88,injury,reoxygenation,inhibit,reperfusion,differentiation
TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.
价 格:¥电议型 号:T9765产 地:中国大陆
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T6S2023HarpagosideCOX,inhibit,Cyclooxygenase,NO Synthase,Harpagoside,NOS,Nitric oxide synthases,Inhibitor
1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression of cyclooxygenase-2 and inducible nitric oxide in HepG2 cells.
价 格:¥电议型 号:T6S2023产 地:中国大陆
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T7420ValifenalateIR-5885,Inhibitor,Valifenalate,inhibit,IR 5885,Bacterial
Valifenalate is antifungal agent, effective against various types of mildew
价 格:¥电议型 号:T7420产 地:中国大陆
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T8449TC-I2000TCI2000,TC-I-2000,TC I2000
TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.
价 格:¥电议型 号:T8449产 地:中国大陆
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T6435CCT129202inhibit,CCT-129202,CCT 129202,Inhibitor,CCT129202,Aurora Kinase
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.
价 格:¥电议型 号:T6435产 地:中国大陆
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TQ0209Ailanthoneinhibit,Inhibitor,Ailanthone,Androgen Receptor
Ailanthone is an effective inhibitor of both full-length androgen receptor (AR) (IC50: 69 nM) and constitutively active truncated AR splice variants (IC50: 309 nM).
价 格:¥电议型 号:TQ0209产 地:中国大陆
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T8202Kaempferol 3-O-gentiobiosideKaempferol 3Ogentiobioside,inhibit,Kaempferol 3 O gentiobioside,Inhibito
Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. It possesses activity against α-glucosidase and displays a carbohydrate enzyme inhibitory effect (IC50: 50 μM).
价 格:¥电议型 号:T8202产 地:中国大陆
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TWS2045Bruceine DParasite,Notch,Apoptosis,Bruceine D,Inhibitor,inhibit
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW199 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.
价 格:¥电议型 号:TWS2045产 地:中国大陆
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T6S2024Harpagideinhibit,Harpagide,Inhibitor,Parasite
1. Harpagide has antibacterial activity. 2. Harpagide has antiviral activity. 3. Harpagide has anti-inflammatory activity.
价 格:¥电议型 号:T6S2024产 地:中国大陆
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TP1299LMelittin TFA(20449-79-0(free base))Melittin TFA(20449 79 0(free base)),Melittin TFA(20449790(free ba
Melittin TFA is a small protein containing 26 amino acid residues, is the principal toxic component of bee venom. Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2.
价 格:¥电议型 号:TP1299L产 地:中国大陆
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TN2202SempervirineSempervirine
Sempervirine can unwind circular DNA, it shows selective inhibition of in vitro synthesis of cancer DNA .
价 格:¥电议型 号:TN2202产 地:中国大陆
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T9720T3Inh-1T3Inh1,T3Inh 1,inhibit,O-glycosylation,Inhibitor,T-3Inh-1,ppGalNAc-T3,breast cancer cells,FGF
T3Inh-1 is an effective and selective inhibitor of ppGalNAc-T3 with an IC50 of 7 ?M. T3Inh-1 prevents breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic side effects.
价 格:¥电议型 号:T9720产 地:中国大陆
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T8206Cycleaninecalcium,Calcium Channel,ICaL,anti-ovarian,Apoptosis,Ca2+ channels,Cycleanine,Ca channels,V
Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.
价 格:¥电议型 号:T8206产 地:中国大陆
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T6920ON123300Platelet-derived growth factor receptor,AMP-activated protein kinase,ON-123300,ON 123300,FGF
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).
价 格:¥电议型 号:T6920产 地:中国大陆